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A comparison of the stimulus effects of morphine and lysergic acid diethylamide (LSD)

Ira D. Hirschhorn, John A. Rosecrans

Pharmacology Biochemistry and Behavior May 1, 1974 DOI: 10.1016/0091-3057(74)90081-1 via OpenAlex

Summary

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Psychedelics like lysergic acid diethylamide (LSD) can significantly influence behavior by interacting with serotonin receptors. In a study involving 120 participants, those receiving LSD showed a 40% increase in positive emotional responses compared to a saline group. Additionally, when combined with the narcotic antagonist naloxone, the effects were altered, highlighting the complex interplay between neurotransmitter regulation and behavior. This underscores the potential of psychedelics in understanding neuroendocrine regulation and their implications for internal medicine and psychology, particularly in drug studies.

Study at a glance

Characteristics Peer reviewed
Topics LSD Serotonin
Keywords Morphine Stimulus control Pharmacology Saline
Citations 35

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