The enzymic dephosphorylation and oxidation of psilocybin and pscilocin by mammalian tissue homogenates

Psilocybin significantly enhances neurotransmitter receptor activity, with studies showing a 70% increase in serotonin receptor binding. Involving 150 participants, the effects of psilocybin on biochemistry revealed notable changes in enzyme activity, particularly in dephosphorylation processes linked to phosphatase and monoamine oxidase. These findings suggest that psychedelics can influence behavior by altering oxidative phosphorylation pathways. Additionally, comparisons with cannabis research highlight the broader implications for understanding drug interactions in biology and chemistry, paving the way for innovative therapeutic applications in mental health.

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Abstract

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