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Insights from the psychedelic experience integration session: Verbatims differentiate 3-month abstinence in alcohol use disorder with depressive symptoms

Maria Garcia Garcia, Dahbia Belahda, Carine Graux, Chris Serrand, Noe Igounenc, Felix Sergent, Thibault Mura, Amandine Luquiens

Journal of Affective Disorders January 19, 2026 DOI: 10.1016/j.jad.2026.121215 via OpenAlex

Summary

AI-generated from the abstract

In psilocybin-assisted psychotherapy, participants who responded to treatment described their experience as an inner dialogue and used adaptive coping strategies, while non-responders focused on sensory and affective details and relied on suppressive coping. The presence of inner dialogue may represent a unique therapeutic mechanism, underscoring the value of preparation and integration in such therapy.

Study at a glance

Characteristics Qualitative study Peer reviewed
Population Participants in psilocybin-assisted psychotherapy
Intervention Psilocybin-assisted psychotherapy
Topics Addiction Depression
Keywords Abstinence Depressive symptoms Psychotherapist Clinical psychology
Key finding Responders to psilocybin-assisted psychotherapy reported narratives of inner dialogue and adaptive coping, whereas non-responders emphasized sensory and affective descriptions and suppressive coping.

Abstract

Responders were distinguished by narratives of inner dialogue and adaptive coping, while non-responders emphasized sensory and affective descriptions and suppressive coping. Inner dialogue may constitute a distinct therapeutic mechanism, highlighting the importance of preparation and integration in psilocybin-assisted psychotherapy.

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