ChemInform Abstract: CHLORIERTE 2‐HYDROXY‐ UND 2‐METHOXY‐PHENOXYAETHYLAMINE, ANALOGA VON PSILOCYBIN
Chemischer Informationsdienst Organische Chemie March 9, 1971 DOI: 10.1002/chin.197110243 via OpenAlex
Summary
AI-generated from the abstractA classical synthetic route converts a phenol (I) into an amine (VI) through a sequence of intermediates (II), (III), (IV), and (V) or alternatively (VII) and (VIII), achieving yields of 60% or 90%, respectively. The resulting amine is then converted to its diazonium salt and decomposed with copper sulfate to yield another phenol (IX). The abstract describes reaction steps and yields without reporting any biological or empirical findings.
Study at a glance
| Characteristics | Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Medicinal chemistry |
| Key finding | The synthetic route from phenol (I) to amine (VI) yields 60% or 90% depending on the pathway, and the amine's diazonium salt is decomposed with CuSO4 to give phenol (IX). |
Abstract
Abstract Nach klassischen Methoden wird aus dem Phenol (I) über die Stufen (II), (III), (IV) und (V) bzw. (VII) und (VIII) das Amin (VI) (60 bzw. 90% Ausbeute) gewonnen, dessen Diazoniumsalz mit CuSO 4 zu dem Phenol (IX) zersetzt wird.