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The Lysing of Catatonia With Intravenous Ketamine Prior to Definitive Treatment With Electroconvulsive Therapy.

Erich J Conrad, Zachary F Stielper, Isabelle V Mermilliod, Matthew R Eng

The journal of ECT April 15, 2025 DOI: 10.1097/YCT.0000000000001151 via PubMed

Summary

AI-generated from the abstract

Catatonia that does not respond to standard medications is often treated with electroconvulsive therapy, but legal delays can postpone this treatment, increasing risks from immobility and leading to procedures like feeding tube placement. A case is presented in which intravenous ketamine successfully resolved catatonia, allowing a patient to avoid complications and additional procedures before receiving electroconvulsive therapy. The authors suggest further research is needed, as ketamine may change the current approach to refractory catatonia.

Study at a glance

Characteristics Case study Case report Peer reviewed
Sample size 1
Population A patient with refractory catatonia
Intervention Intravenous ketamine
Topics Ketamine
Keywords #ketamine-therapy ketamine treatment Ketamine infusion #catatonia-treatment catatonic syndrome Catatonic state #ect electroconvulsive therapy
Key finding Intravenous ketamine successfully resolved catatonia in a patient, allowing avoidance of complications and procedures before definitive electroconvulsive therapy.

Abstract

The presence of catatonia refractory to routine pharmacologic management is often subsequently managed by electroconvulsive therapy. However, legal obstacles that delay the initiation of electroconvulsive therapy in a timely fashion may be present. This may lead to prolonged risks associated with immobility and result in other procedures such as percutaneous endoscopic gastrostomy (PEG) tube placement. We present a case of successful lysing of catatonia with intravenous ketamine that allowed a patient to avoid potential complications and other procedures prior to definitive treatment with electroconvulsive therapy. Further research of this potential treatment of catatonia is needed as this may change the current approach to refractory catatonia.

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