Psilocybin use in bipolar disorder: A comprehensive review
André Do, Laurence Cloutier, Lydia Hébert‐tremblay, Christel Thauvin
Journal of Affective Disorders October 31, 2025 DOI: 10.1016/j.jad.2025.120485 via OpenAlex
Summary
AI-generated from the abstractThe therapeutic value of psilocybin for treating depression in bipolar disorder remains uncertain, as its efficacy and safety have not been established. Future research is necessary to determine whether psilocybin can be a viable treatment option for bipolar depression.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Depression economics Hallucinogen Bipolar disorder Bipolar illness |
| Citations | 1 |
| Key finding | The efficacy and safety of psilocybin for bipolar depression remain unclear, and more research is needed to clarify its therapeutic value. |
Abstract
Despite its promising potential, the efficacy and safety of psilocybin in the treatment of BD depression remain unclear, and future research is essential to clarify its therapeutic value in BD.