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Active Constituents of Psilocybin Mushroom Edibles

Richard B. van Breemen, Daniel Simchuk, Bjorn Fritzsche, Daniel Huson, Scott Kuzdzal, J. W. Ferguson

JAMA Network Open September 11, 2025 DOI: 10.1001/jamanetworkopen.2025.31345 via OpenAlex

Summary

AI-generated from the abstract

Unregulated psilocybin mushroom edibles contain a range of active constituents beyond psilocybin and psilocin, including baeocystin, norbaeocystin, and aeruginascin, with variable concentrations across products. The analysis of these edibles reveals inconsistent labeling and dosing, posing potential risks for consumers.

Study at a glance

Characteristics Case series Case report Peer reviewed
Population Unregulated psilocybin mushroom edibles
Citations 1
Key finding Unregulated psilocybin mushroom edibles contain multiple active alkaloids with inconsistent concentrations and labeling.

Abstract

This case series evaluates the active constituents of unregulated psilocybin mushroom edibles.

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