Tryptamines
Javed Khan, Thomas J. Kennedy, Donnell R. Christian
Humana Press eBooks August 26, 2011 DOI: 10.1007/978-1-59745-437-7_15 via OpenAlex
Summary
AI-generated from the abstractTryptamine analogs, both natural and synthetic, form a class of hallucinogenic drugs derived from indole. The forensic identification of several specific compounds—psilocin, psilocybin, bufotenin, 5MeODMT, 5MeODIPT (foxy methoxy), DET, and AET—is described. Structural formulas are presented alongside a discussion of short- and long-term physical and psychological effects of abuse. A complete list of plants containing tryptamine analogs is included. Chemical screening using Weber's test is described, along with extraction techniques for thin-layer chromatography, GCMS, and FTIR analysis.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Tryptamines Indole test Stereochemistry Hallucinogen |
| Citations | 2 |
| Key finding | Tryptamine analogs are hallucinogenic indole-derived drugs that can be forensically identified using Weber's test, extraction, and chromatographic or spectroscopic methods. |
Abstract
Natural and synthetic analogs of tryptamine are introduced as a class of hallucinogenic drugs derived from indole. The forensic identification of psilocin, psilocybin, bufotenin, 5-methoxy-N,N-dimethyltryptamine (5MeODMT), 5-methoxy-N,N-diisopropyltryptamine (5MeODIPT, aka foxy methoxy), N,N-diethyltryptamine (DET), and alpha-ethyltryptamine (AET) is discussed. Structural formulas are provided with a discussion of the short- and long-term physical and psychological effects of abuse. A complete list of plants containing tryptamine analogs is included. Chemical screening using Weber's test is described along with extraction techniques typically used to isolate tryptamines for thin-layer chromatography, GCMS, and FTIR analysis.