Psilocybin therapy appears as effective as escitalopram, small study finds
Pharmaceutical journal/The pharmaceutical journal January 1, 2021 DOI: 10.1211/pj.2021.1.91592 via OpenAlex
Summary
AI-generated from the abstractA small phase II trial published in the New England Journal of Medicine found that psilocybin therapy is at least as effective as the antidepressant escitalopram for treating depression. Participants received either two sessions of psilocybin therapy in a specialist clinical setting or a course of escitalopram. The results suggest comparable antidepressant effects between the two treatments.
Study at a glance
| Characteristics | Phase II randomized controlled trial Peer reviewed |
|---|---|
| Population | Adults with depression |
| Interventions | Psilocybin therapy Escitalopram |
| Topics | Anxiety Psilocybin |
| Keywords | Escitalopram Medicine Psychiatry Psychology |
| Key finding | Psilocybin therapy appears to be at least as effective as escitalopram in treating depression. |
Abstract
Psilocybin therapy appears to be at least as effective as escitalopram in treating depression, findings from a small phase II study published in the New England Journal of Medicine have indicated (15 April 2021)[1]. Researchers compared two sessions of psychedelic psilocybin therapy, delivered in a specialist clinical setting, with a course of the selective serotonin […]