Biotransformation of Tryptamine in Fruiting Mycelia ofPsilocybe cubensis
Planta Medica June 1, 1989 DOI: 10.1055/s-2006-961995 via OpenAlex
Summary
AI-generated from the abstractMycelial cultures of Psilocybe cubensis that can produce psilocybin and psilocin from scratch also convert externally supplied tryptamine into psilocin, reaching up to 3.3% of the dry mass of the resulting fruit bodies. Analysis by HPLC and TLC shows these mushrooms contain only a small amount of psilocybin (0.01–0.2% dry mass), while the psilocin levels are the highest reported in any mushroom.
Study at a glance
| Characteristics | Laboratory study Peer reviewed |
|---|---|
| Population | Mycelial cultures of Psilocybe cubensis |
| Topics | Psilocybin |
| Keywords | Tryptamine Mycelium Biotransformation Chromatography |
| Citations | 13 |
| Key finding | Feeding tryptamine to Psilocybe cubensis mycelial cultures yields fruit bodies with psilocin levels up to 3.3% dry mass, the highest described in any mushroom. |
Abstract
Mycelial cultures of PSILOCYBE CUBENSIS, with the ability to form psilocybin and psilocin DE-NOVO, also hydroxylated and methylated fed tryptamine to give psilocin in up to 3.3% dry mass of the obtained fruit bodies. By using HPLC and TLC, it was found that these mushrooms contain only a small amount of psilocybin (0.01-0.2% dry mass). The values of psilocin are the highest described in any mushrooms.