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EXPRESSION OF CONCERN: Efficacy of psilocybin for treating symptoms of depression: systematic review and meta-analysis

BMJ May 4, 2024 DOI: 10.1136/bmj.q1025 via OpenAlex

Summary

AI-generated from the abstract

A methodological error in the calculation of standardised mean differences likely overestimated the benefits of psilocybin for depression in adults. The authors are reviewing and responding to the error and its implications for the findings and conclusions of the paper. The BMJ will decide what further action is needed.

Study at a glance

Characteristics Meta-analysis Randomized Peer reviewed
Population Adults with depression
Intervention Psilocybin
Topics Psilocybin
Keywords Meta-analysis Depression economics Psychiatry Clinical trial
Citations 2
Key finding A calculation error in standardised mean differences likely overestimated the benefits of psilocybin for depression.

Abstract

The journal and the authors are investigating the problem.The study analysed data from randomised trials of psilocybin for the treatment of depression in adults.A methodological concern has been raised about an error in the calculation of standardised mean differences.This is likely to have overestimated the benefits of psilocybin.The authors are reviewing and responding to the error and its implications for the findings and conclusions of the paper.The authors' response will be reviewed by The BMJ who will decide what further action is needed.

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