Psilocybin for Depression: The ACE Model Manual

This document describes the structure, procedures, and scripts used in the two Imperial College London Psilodep studies, which investigated psilocybin treatment for major depression. It serves as a manual detailing the therapeutic approach, including session structure, preparation, and integration phases, as well as specific scripts for guiding participants through the psychedelic experience. The manual is based on the clinical protocols developed for these trials, providing a standardized framework for administering psilocybin in a therapeutic context for depression.

Study at a glance

Abstract

"The Psilocybin for Depression: The ACE Manual '' describes the structure, procedures, and scripts used in the two Imperial College London studies (Psilodep) researching psilocybin treatment for major depression.