The Role of Psychedelics in Contemporary Psychological and Interdisciplinary Inquiry.
Kerem Kemal Soylemez, Emma Marie De Boo, Aysil Susuzlu, Joanne Lusher
J Pers Med September 28, 2025 DOI: 10.3390/jpm15100450 via PubMed Central
Summary
AI-generated from the abstractPsychedelic compounds are being reexamined for their psychological and neurobiological effects. Evidence suggests they can treat mood disorders, PTSD, and addiction by enhancing neuroplasticity and disrupting maladaptive cognitive patterns. Psychologically, they facilitate introspection and emotional processing; neuroscientific findings show altered brain network dynamics. Anthropological and philosophical perspectives contextualize their cultural and existential significance. In medicine, they offer novel interventions for chronic pain and palliative care. The review calls for rigorous, ethically grounded research to explore psychedelics' potential in reshaping mental health paradigms and cognitive science.
Study at a glance
| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Anxiety Psychedelic-assisted therapy |
| Keywords | Psychedelic treatment Hallucinogen therapy Entheogen therapy Psychedelic medicine |
| Citations | 2 |
| Key finding | Psychedelics show efficacy in treating mood disorders, PTSD, and addiction by enhancing neuroplasticity and disrupting maladaptive cognitive patterns, and offer novel interventions for chronic pain and palliative care. |
Abstract
Psychedelic compounds are gaining renewed attention across disciplines for their profound psychological and neurobiological effects. Emerging research highlights their efficacy in treating mood disorders, PTSD, and addiction by enhancing neuroplasticity and disrupting maladaptive cognitive patterns. From a psychological standpoint, psychedelics facilitate introspection, emotional processing, and therapeutic breakthroughs. Neuroscientific findings reveal altered brain network dynamics, while anthropological and philosophical perspectives contextualize their cultural and existential significance. In medicine, they offer novel interventions for chronic pain and palliative care. The present review article underscores the need for rigorous, ethically grounded research to explore psychedelics' potential in reshaping mental health paradigms and cognitive science from a multidisciplinary perspective.