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Psychedelics as a treatment for disorders of consciousness

Gregory Scott, Robin Carhart‐Harris

Neuroscience of Consciousness January 1, 2019 DOI: 10.1093/nc/niz003 via OpenAlex

Summary

AI-generated from the abstract

The classic psychedelic psilocybin may increase conscious awareness in patients with disorders of consciousness, based on its ability to increase brain complexity—a reliable index of conscious level. The authors propose testing this hypothesis but also confront the considerable ethical and practical challenges that must be addressed for direct assessment.

Study at a glance

Characteristics Theoretical or philosophical paper Peer reviewed
Intervention Psilocybin
Topics Psilocybin
Keywords Persistent vegetative state Level of consciousness Cognitive psychology Consciousness disorders
Citations 72
Key finding Psilocybin may increase conscious awareness in patients with disorders of consciousness by increasing brain complexity, but ethical and practical challenges must be addressed.

Abstract

Based on its ability to increase brain complexity, a seemingly reliable index of conscious level, we propose testing the capacity of the classic psychedelic, psilocybin, to increase conscious awareness in patients with disorders of consciousness. We also confront the considerable ethical and practical challenges this proposal must address, if this hypothesis is to be directly assessed.

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