Comparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying
Mary M. Sweeney, Sandeep M. Nayak, Ethan Hurwitz, Lisa N. Mitchell, Thomas Cody Swift, Roland R. Griffiths
PLoS ONE August 24, 2022 DOI: 10.1371/journal.pone.0271926 via OpenAlex
Summary
AI-generated from the abstractPsychedelic drug experiences and near-death or other non-ordinary experiences both change people's beliefs about death, but direct comparisons are rare. In a survey of 3,192 individuals who reported such experiences, those from non-drug causes (e.g., near-death) were more likely to involve unconsciousness, clinical death, or imminent danger. Both groups reported similar reductions in fear of death, high personal meaning, spiritual significance, and psychological insight. However, psychedelic participants scored higher on standardized measures of mystical and near-death features, while non-drug participants more often rated their experience as the single most meaningful of their lives. Among psychedelics, ayahuasca and DMT produced stronger positive enduring effects than psilocybin and LSD.
Study at a glance
| Characteristics | Cross-sectional survey Peer reviewed |
|---|---|
| Sample size | 3,192 |
| Population | Individuals who reported an experience that altered their beliefs about death, occasioned by a psychedelic drug or a near-death or other non-ordinary experience |
| Topics | LSD Mysticism Psilocybin |
| Keywords | Medicine Clinical psychology |
| Citations | 60 |
| Key finding | Both psychedelic and non-drug experiences that change death attitudes produce similar reductions in fear of death and high ratings of personal meaning, though psychedelic experiences show greater mystical and near-death features. |
Abstract
Both psychedelic drug experiences and near-death experiences can occasion changes in perspectives on death and dying, but there have been few direct comparisons of these phenomena. This study directly compared psychedelic occasioned and non-drug experiences which altered individuals’ beliefs about death. Individuals who reported an experience that altered their beliefs about death occasioned by either a psychedelic drug or a near-death or other non-ordinary experience completed an online survey. Circumstances of the experience, mystical and near-death subjective features, changes in attitudes about death, and other persisting effects were evaluated. The study sample ( n = 3192) included five groups: non-drug near-death or other non-ordinary experiences ( n = 933), and drug experiences occasioned by lysergic acid diethylamide (LSD) ( n = 904), psilocybin ( n = 766), ayahuasca ( n = 282), or N , N- dimethyltryptamine (DMT) ( n = 307). Analyses of differences in experiences were adjusted statistically for demographic differences between groups. Compared to the psychedelic groups, the non-drug group was more likely to report being unconscious, clinically dead, and that their life was in imminent danger. The groups were remarkably similar in the reported changes in death attitudes attributed to the experience, including a reduced fear of death and high ratings of positive persisting effects and personal meaning, spiritual significance, and psychological insight. Although both psychedelic and non-drug participants showed robust increases on standardized measures of mystical and near-death experiences, these measures were significantly greater in the psychedelic participants. Non-drug participants were more likely to rate their experiences as the single most meaningful of their lives. Comparing across psychedelic substances, ayahuasca and DMT groups tended report stronger and more positive enduring consequences of the experience than the psilocybin and LSD groups, which were largely indistinguishable. These data provide a detailed characterization and comparison of psychedelic occasioned and non-drug experiences that changed attitudes about death and suggest the importance of future prospective psychedelic administration studies.