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Significant Psychedelic Experiences Evaluated for Mystical Characteristics Associated with Cannabis Use Reduction and Psychological Flexibility Improvement: A Naturalistic Cross-Sectional Retrospective Survey.

B Romeo, E Kervadec, B Fauvel, L Strika-Bruneau, A Amirouche, V Verroust, P Piolino, A Benyamina

Journal of psychoactive drugs July 3, 2024 DOI: 10.1080/02791072.2024.2375720 via PubMed

Summary

AI-generated from the abstract

Among 152 cannabis users who had a significant past psychedelic experience, an online retrospective survey found that after the experience there was a sustained reduction in cannabis use disorder scores, frequency of use, and daily intoxication duration. The reduction in cannabis use during the first month was linked to the intensity of the mystical experience. Participants also reported lasting improvement in psychological flexibility, which was correlated with mystical experience intensity. The findings suggest naturalistic psychedelic experiences may lead to decreased cannabis use, possibly through increased psychological flexibility and mystical experience intensity.

Study at a glance

Characteristics Retrospective survey Cross-sectional Peer reviewed
Sample size 152
Population Cannabis users who reported a significant psychedelic experience
Topics Addiction Cannabis
Keywords Cannabis use disorder Psychedelic Psychological flexibility
Citations 5
Key finding Naturalistic psychedelic experiences were followed by sustained reductions in cannabis use and improvements in psychological flexibility, with the intensity of the mystical experience associated with early cannabis reduction.

Abstract

Treating cannabis use disorder remains a significant challenge in the field of addiction medicine. Some recent studies point to psychedelic-assisted psychotherapy as a potential treatment option for substance use disorders. The objective of this study was therefore to explore the impact of naturalistic psychedelic experiences on cannabis use and psychological flexibility. An online retrospective survey was carried out on 152 cannabis users who also reported a significant experience induced by psychedelics in the past. Following a psychedelic experience, there was a significant and sustained reduction of average CUDIT score (p < .001), frequency of cannabis use (p < .001), and acute duration of daily intoxication (p < .001). Cannabis use reduction during the first month post-experience was significantly associated with the intensity of the mystical experience (p = .01). Participants reported a concomitant increased lasting improvement of psychological flexibility following the experience (p < .001), which was correlated to the intensity of the mystical experience during the first month post-experience (p = .04). This study demonstrates that naturalistic psychedelic experiences may be followed by a decrease in cannabis use. Positive health outcomes appear potentially connected to the intensity of the mystical experience, as well as an improvement in psychological flexibility.

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