Double-Blind Comparison of the Two Hallucinogens Dextromethorphan and Psilocybin: Experience-Dependent and Enduring Psychological Effects in Healthy Volunteers
Samantha Hilbert, David S. Mathai, Nathan D. Sepeda, Justin C. Strickland, Roland R. Griffiths, Albert Garcia‐romeu
Psychedelic Medicine August 30, 2023 DOI: 10.1089/psymed.2023.0035 via OpenAlex
Summary
AI-generated from the abstractDissociatives like dextromethorphan may have clinical applications when used in supportive settings similar to those in psychedelic research, which prioritize optimizing psychologically valuable drug experiences. The analysis suggests that such contexts could enhance therapeutic outcomes.
Study at a glance
| Characteristics | Analysis Double-blind Peer reviewed |
|---|---|
| Topics | Psilocybin |
| Keywords | Dextromethorphan Hallucinogen Psychotherapist Clinical psychology |
| Citations | 10 |
| Registration | NCT02033707 |
| Key finding | Dissociatives may have clinical utility when explored within supportive contexts characteristic of psychedelic research. |
Abstract
This analysis suggests the utility of exploring clinical applications of dissociatives that occur within the supportive contexts that are characteristic of psychedelic research and that prioritize the optimization of psychologically valuable drug experiences. This study was registered with ClinicalTrials.gov (NCT02033707).