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Psychological Mediators of Reduced Distress: Preregistered Analyses from a Randomized Controlled Trial of a Smartphone-Based Well-Being Training.

Matthew J Hirshberg, Cortland J Dahl, Daniel Bolt, Richard J Davidson, Simon B Goldberg

Clinical psychological science : a journal of the Association for Psychological Science January 1, 2025 DOI: 10.1177/21677026241233262 via PubMed

Summary

AI-generated from the abstract

A four-week smartphone-based meditation intervention reduced psychological distress in adults, most of whom had clinical anxiety or depressive symptoms during the early COVID-19 pandemic. The intervention improved four proposed mediators—mindful action, loneliness, cognitive defusion, and purpose—which together accounted for 21.9% to 62.5% of the effect on distress at three-month follow-up. In a multiple mediator analysis, reduced loneliness alone explained 61.7% of the combined indirect effect. The findings suggest multiple psychological pathways may mediate distress reduction in digital meditation-based interventions.

Study at a glance

Characteristics Randomized controlled trial Preregistered Peer reviewed
Sample size 662
Population Adults with clinical levels of anxiety or depressive symptoms
Duration 4-week intervention, 3-month follow-up
Topics Meditation
Keywords Distress Mechanisms Mediation Mobile health
Citations 9
Key finding Assignment to a four-week smartphone-based meditation intervention predicted gains on four psychological mediators, which in turn mediated follow-up distress, with reduced loneliness accounting for 61.7% of the combined indirect effect.

Abstract

Understanding why interventions work is essential to optimizing them. Although mechanistic theories of meditation-based interventions (MBIs) exist, empirical evidence is limited. We randomly assigned 662 adults (79.9% reported clinical levels of anxiety or depressive symptoms) to a four-week smartphone-based MBI or wait-list control condition early in the COVID-19 pandemic. Psychological distress and four theory driven preregistered psychological mediators of well-being (mindful action, loneliness, cognitive defusion and purpose) were assessed five times during the intervention period and at three-month follow-up. In preregistered analyses, assignment to the intervention predicted significant gains on all mediators which in turn significantly mediated follow-up distress (21.9%-62.5% of intervention effect on distress). No significant mediation pathway was observed in an exploratory multiple mediator analysis, but reduced loneliness accounted for 61.7% of the combined indirect effect. Multiple psychological pathways may mediate reduced distress in a digital MBI.

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