2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets sold on the Swiss black market.
C Giroud, M Augsburger, L Rivier, P Mangin, F Sadeghipour, E Varesio, J L Veuthey, P Kamalaprija
Journal of analytical toxicology September 1, 1998 DOI: 10.1093/jat/22.5.345 via PubMed
Summary
AI-generated from the abstractTwo sets of tablets from the Swiss black market were analyzed to identify 4-bromo-2,5-dimethoxyphenethylamine (2C-B) using multiple analytical methods including GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR. Only a combination of mass spectrometry and NMR provided unequivocal identification. Quantitation by HPLC-DAD and CE-DAD showed the tablets contained 3 to 8 mg of 2C-B, which is within the minimum amount needed to produce the drug's characteristic effects.
Study at a glance
| Characteristics | Analytical study Peer reviewed |
|---|---|
| Population | Two sets of tablets from the Swiss black market |
| Dose | 3-8 mg |
| Keywords | 2c-b Drug identification Illicit drugs Drug dosage |
| Citations | 57 |
| Key finding | 2C-B was identified in tablets from the Swiss black market at doses of 3-8 mg, within the range needed for psychoactive effects. |
Abstract
This study sought to identify, by means of several analytical methods (GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC-DAD and CE-DAD. The amounts of 2C-B found in the tablets (3-8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this drug.