Neo-clerodane diterpenes from the hallucinogenic sage Salvia divinorum.
Osamu Shirota, Kumi Nagamatsu, Setsuko Sekita
Journal of natural products December 1, 2006 DOI: 10.1021/np060456f via PubMed
Summary
AI-generated from the abstractSeven previously unknown neo-clerodane diterpenes—salvidivins A–D, salvinorins H and I, and divinatorin F—along with eight known compounds, were isolated from the hallucinogenic plant Salvia divinorum. Chemical structures of the new compounds were determined using two-dimensional nuclear magnetic resonance spectroscopy. These findings expand the known chemical diversity of this plant, which is of interest for its psychoactive properties.
Study at a glance
| Characteristics | Phytochemical study Peer reviewed |
|---|---|
| Population | Salvia divinorum plant material |
| Keywords | Salvia divinorum chemistry Salvia divinorum compounds Salvia divinorum phytochemistry Salvia divinorum constituents Neo-clerodane diterpenes |
| Citations | 68 |
| Key finding | Seven new neo-clerodane diterpenes were isolated and structurally characterized from Salvia divinorum. |
Abstract
Seven new neo-clerodane diterpenes, salvidivins A (2), B, (3), C (4), and D (5), salvinorins H (6) and I (7), and divinatorin [corrected] F (8), along with eight known neo-clerodane diterpenes, salvinorins A (1)-F, divinatorins A and B, and seven other constituents, were isolated from the hallucinogenic sage Salvia divinorum. The structures of 1-7 were elucidated on the basis of 2D NMR spectroscopic studies.