Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?
J Psychopharmacol April 22, 2021 Robin L Carhart-Harris, Anne C Wagner, Manish Agrawal et al. 54 citations
Psychedelic therapy is experiencing a resurgence due to favorable regulations, policy changes, and positive trial results, but current confirmatory trials may not fully address safety and best practice. The authors recommend supplementing these trials with pragmatic trials, real-world data initiatives, and digital health solutions to discover optimal and personalized treatment protocols. These steps aim to develop safe, effective, and cost-efficient psychedelic therapy, which is susceptible to hype and regulatory challenges given its history.