Psilocybin use is growing globally, and recent research shows promise for treating mental disorders. Analyzing 846 public online self-reports with textual analysis software, five clusters emerged describing mental experiences, cognitive processes, somatic experiences, perceptual alterations, and context of administration. The findings reinforce that psilocybin experiences commonly involve somatic and visual changes, feelings of connectedness and oneness with the world, the importance of setting, beneficial mystical experiences, and the phenomenon of ego dissolution. Understanding these circumstances may guide clinical use and harm reduction.
The paper explores the relationships among DMT-induced experiences, psychosis, healing, mystical experiences, and positive emotionality. It examines how DMT can serve as a model for psychosis and as a therapeutic tool, while also considering the overlap between these models and mystical experiences. The authors discuss the potential for DMT to induce states resembling psychosis but also to facilitate healing and positive emotional outcomes, suggesting that the context and set and setting are crucial in determining whether the experience leads to distress or well-being.