Journal of medical Internet research
February 20, 2024
Huijing Zou, Sek Ying Chair, Bilong Feng et al.
15 citations
A social media-based mindfulness program (MCARE) added to usual care reduced depression and anxiety more than usual care alone in 178 patients with acute coronary syndrome. At six weeks, depression dropped substantially (Cohen's d = -1.28) and anxiety dropped moderately (Cohen's d = -0.83); these benefits persisted at 12 weeks. The program also improved psychological stress, physical and emotional quality of life, dietary behavior, physical activity, and systolic blood pressure. About 76% of participants completed at least five of six sessions, and over 93% rated the program acceptable. The findings suggest that integrating a mindfulness intervention delivered partly through WeChat can help manage psychological distress and improve cardiovascular risk factors in this population.
Journal of psychiatry & neuroscience : JPN
January 1, 2024
Jinsong Tang, Qiuxia Wu, Chang Qi et al.
7 citations
Chronic, non-medical use of ketamine is associated with widespread thinning of the brain's outer layer, the cortex. Compared with healthy controls, 95 people with ketamine use disorder showed reduced cortical thickness in many regions, most extensively in the frontal and parietal lobes, including the dorsolateral prefrontal cortex and precuneus. No areas of increased thickness were observed. Greater estimated lifetime ketamine consumption correlated with thinner cortex in the right inferior parietal and right rostral middle frontal regions. These findings highlight potential long-term structural brain changes from non-medical ketamine use and serve as a reference for its antidepressant use.
medRxiv Preprint Server
February 21, 2021
Jinsong Tang, Qiuxia Wu, Chang Qi et al.
preprint
Long-term, non-medical use of ketamine is associated with reduced gray matter in the dorsal prefrontal cortex, and this study investigated whether similar cortical thinning occurs. Chronic ketamine users showed cortical thickness abnormalities compared to non-users, suggesting that recreational ketamine use may lead to structural brain changes beyond gray matter volume loss. The findings indicate potential neurotoxic effects of sustained illicit ketamine use on brain health, as observed through MRI scans.