A nanoemulsion of THC was created using a solvent displacement technique, yielding droplets of about 190 nm that remained colloidally stable for at least six weeks. The liquid nanoemulsion was converted into a solid powder that could be redispersed in water without phase separation, retaining its THC potency. This solid format is suited for microdosing, a practice that might separate THC's health benefits from its psychotropic effects.
A THC-loaded nanoemulsion was created using an ethanol-assisted method without specialized equipment, producing lipid droplets averaging 190 nm. The nanoemulsion remained colloidally stable for at least six weeks, with no significant loss of cannabinoid potency. It withstood heat, freeze/thaw cycles, carbonation, dilution, high sucrose, and a pH range of 5-8. The nanoemulsion was converted into a water-soluble powder via lyophilization and ball-milling, suitable for microdosing applications. The powder was freely redispersible in water without phase separation, though it had limited free-flowing behavior.