Hallucinogen-persisting perception disorder
Therapeutic Advances in Psychopharmacology October 1, 2012 Leo Hermle, Melanie Simon, Martin Ruchsow et al.
A woman who abused LSD for a year at age 18 developed hallucinogen-persisting perception disorder (HPPD) with after images, peripheral movement perception, blurring, halos, and size distortions. Antidepressants and risperidone did not help, but lamotrigine almost completely resolved the visual disturbances. The authors suggest lamotrigine, an antiepileptic with neuroprotective and mood-stabilizing effects, may be a promising new treatment for HPPD.