Acute effects of BZP, TFMPP and the combination of BZP and TFMPP in comparison to dexamphetamine on an auditory oddball task using electroencephalography: a single-dose study
Psychopharmacology March 1, 2016 HeeSeung Lee, Grace Y. Wang, Louise E. Curley et al.
A single oral dose of either TFMPP or dexamphetamine significantly reduced the P300 amplitude, a measure of brain electrical activity related to attention and information processing. A similar trend was observed with BZP alone. However, the combination of BZP and TFMPP had no effect on P300 amplitude. Neither P300 latency nor reaction time was affected by any drug treatment, nor were earlier sensory components P100 and P200. The findings suggest that BZP and TFMPP, but not their combination, affect auditory sensory-evoked P300 potential in a manner similar to dexamphetamine.