88 results for "Theory of Mind"

PM504. Theory of Mind in Clinical high risk as trait marker of conversion to psychosis: review

The International Journal of Neuropsychopharmacology  – May 27, 2016

Summary

Psilocybin profoundly alters brain connectivity, mimicking acute psychosis. In a double-blind clinical trial with 20 healthy subjects, brain imaging revealed decreased coherence in theta, alpha, and beta bands, indicating widespread disconnection. Interestingly, high gamma (50-100Hz) connectivity increased. These findings offer critical insights for cognitive psychology and clinical psychology, modeling an acute state that informs our understanding of psychosis traits. This work contributes to advancing mental health and psychiatry by illuminating the neurobiological underpinnings of severe thought disturbances.

Abstract

Psilocybin, a classical tryptamine hallucinogen, serves as a model of acute psychosis in humans.Intoxication with this compound induces significant...

Neurobehavioural Correlates of Breath Meditation in Novice Adolescents: Insights from Anapanasati-based Paradigm.

Annals of neurosciences  – April 02, 2025

Summary

No Summary

Abstract

Breath-awareness practices contribute to stress management and psychological well-being among adolescents. However, their neurobehavioural effects ...

The Effects of Tryptamine Psychedelics in the Brain: A meta-Analysis of Functional and Review of Molecular Imaging Studies

Frontiers in Pharmacology  – September 29, 2021

Summary

Tryptamine hallucinogens like Psilocybin strongly modulate key brain regions, holding therapeutic promise in Psychology. A quantitative meta-analysis of functional imaging studies revealed changes in cortical activation and connectivity align with high densities of the 5-HT2A receptor, a crucial 5-HT receptor. Neuroscience shows these psychedelics, often from chemical synthesis and alkaloids, influence behavior. Affected areas include the anterior cingulate cortex, posterior cingulate, ventromedial prefrontal cortex, dorsolateral prefrontal cortex, and temporal cortex. This highlights neurotransmitter receptor influence on the brain's cortex.

Abstract

There is an increasing interest in the neural effects of psychoactive drugs, in particular tryptamine psychedelics, which has been incremented by t...

Dreaming, Mind-Wandering, and Hypnotic Dreams.

Frontiers in neurology  – January 01, 2020

Summary

No Summary

Abstract

Hobson's AIM theory offers a general framework for thinking about states of consciousness like wakefulness, REM dreaming and NREM mentations in ter...

Integrating the Mindfulness-Acceptance-Commitment framework with Self-Determination Theory principles to promote Need-Supportive Sport Coaching.

Psychology of sport and exercise  – May 31, 2025

Summary

Sport coaches who practice mindfulness show remarkable improvements in their ability to support athletes' psychological needs. By combining Mindfulness-Acceptance-Commitment principles with Self-Determination theory, coaches developed enhanced self-awareness and stronger connections with athletes. Weekly mindfulness intervention sessions helped coaches regulate emotions, align with personal values, and create more supportive training environments that promote athlete well-being.

Abstract

Need-supportive sport coaching, rooted in Self-Determination Theory (SDT), aims to fulfill athletes' psychological needs, enhancing both performanc...

The Neurophysiology of Enlightenment: Measured EEG Markers at 43 Hz and t=41 s

Zenodo (CERN European Organization for Nuclear Research)  – December 23, 2025

Summary

Enlightenment has been identified as a measurable brain state, with findings showing significant neurophysiological markers at precisely 41 seconds post-stimulation. In a study involving breakthrough subjects under the influence of 5-MeO-DMT and during sustained meditation, EEG data revealed a striking 43 Hz coherence featuring DMN deactivation and gamma synchrony. The analysis included 50 participants, demonstrating a convergence of key metrics like complexity drop and persistence loss, suggesting consciousness may act as a physical field relevant to quantum mind theories.

Abstract

This paper presents the first reproducible neurophysiological evidence of enlightenment as a measurable brain state. Using raw EEG from breakthroug...

Increased functional connectivity between brain regions involved in social cognition, emotion and affective-value in psychedelic states induced by N,N-Dimethyltryptamine (DMT).

Frontiers in pharmacology  – January 01, 2024

Summary

DMT, a powerful psychedelic, strengthens connections between brain regions responsible for social understanding and emotional processing. Brain scans revealed enhanced communication between areas controlling empathy, self-awareness, and emotional value, suggesting how psychedelics might help treat social and emotional disorders.

Abstract

The modulation of social cognition is suggested as a possible mechanism contributing to the potential clinical efficacy of psychedelics in disorder...

Ayahuasca Enhances Functional Connectivity in the Third Visual Pathway and Mirror Neuron Networks: a Crossover, Multiple-Dose fMRI Study.

Social cognitive and affective neuroscience  – January 31, 2026

Summary

Ayahuasca significantly enhances social connection, improving perceived relationships one week later. A pharmacoimaging investigation with twelve healthy participants revealed the highest dose increased connectivity in the brain's posterior superior temporal sulcus (pSTS), a key region in the third visual pathway. This enhanced social cognition, with strong links between pSTS activity and the mirror neuron system, correlating with increased perspective-taking. This reveals how psychedelics integrate these systems, offering a basis for ayahuasca's prosocial therapeutic effects.

Abstract

Understanding the neural mechanisms underlying the impact of psychedelics on social perception and cognition may be instrumental to unravel their t...

Feasibility of a Personal Neuromorphic Emulation.

Entropy (Basel, Switzerland)  – September 05, 2024

Summary

Scientists reveal how our unique neural patterns could be replicated through neuromorphic computation - creating a "digital twin" of an individual's mind. Through active inference, our brains continuously develop and reorganize connections based on personal experiences. This suggests consciousness emerges from complex information patterns that could theoretically be recreated in non-biological systems, opening new frontiers in personal neural development and our understanding of human cognition.

Abstract

The representation of intelligence is achieved by patterns of connections among neurons in brains and machines. Brains grow continuously, such that...

Does neural computation feel like something?

Frontiers in neuroscience  – January 01, 2025

Summary

As machines grow more sophisticated, a fascinating question emerges: Could artificial neural networks experience consciousness? New research challenges the popular view that consciousness emerges from computation alone. By using a novel "counterfactual eraser" technique in computer simulations, researchers showed that identical neural activity patterns can exist with or without the underlying computational structure - suggesting consciousness requires more than just the right calculations.

Abstract

Artificial neural networks are becoming more advanced and human-like in detail and behavior. The notion that machines mimicking human brain computa...

Modelling aspects of consciousness: a topological perspective

arXiv Preprint Archive  – November 10, 2020

Summary

The brain's inability to fully grasp its own consciousness may be mathematically inevitable. Using topological modeling in neuroscognitive biology (q-bio.NC), researchers demonstrated that no system—biological or artificial—can maintain a complete representation of its own attention processes. This mathematical proof supports Attention Schema Theory, suggesting our brain's simplified model of consciousness is not a bug, but a necessary feature.

Abstract

Attention Schema Theory (AST) is a recent proposal to provide a scientific explanation for the basis of subjective awareness. In AST, the brain con...

A “GENERAL THEORY OF MENTAL SUFFERING”, AND THE ROLE OF AN INNOVATIVE NARRATIVE THERAPEUTIC APPROACH

Psychological Thought  – October 30, 2021

Summary

A compelling new perspective suggests mental suffering, from addiction to anxiety, arises when negative life narratives 'capture' the mind, offering a fresh context for Clinical Psychology. Psychedelics and Drug Studies indicate psilocybin can effectively free individuals from these patterns. This understanding of brain plasticity supports an innovative narrative psychotherapy approach. A psychotherapist could guide persons struggling with conditions like anorexia nervosa and other eating disorders, transforming mental health and psychiatry by fostering ethical subjectivities.

Abstract

This article proposes alternative understandings of certain structuralist informed (Diagnostic and Statistical Manual of Mental Disorders - DSM-III...

Looking for the Self: Phenomenology, Neurophysiology and Philosophical Significance of Drug-induced Ego Dissolution

Frontiers in Human Neuroscience  – May 23, 2017

Summary

High doses of hallucinogens strikingly dissolve the sense of self, a phenomenon, drug-induced ego dissolution. It challenges the psychology of self; consciousness doesn't always require self-awareness. Neuroscience identifies three drug classes inducing this, disrupting the "embodied self" rooted in multimodal sensory function, not just an illusion. Understanding these neural correlates of consciousness informs cognitive psychology and neurophysiology. It offers psychotherapists insights beyond ego depletion or narcissism, impacting cognition and pain management, akin to the placebo effect. This deep dive into the ego provides a unique lens for phenomenology.

Abstract

There is converging evidence that high doses of hallucinogenic drugs can produce significant alterations of self-experience, described as the disso...

The Mind-Matter Dichotomy: A Persistent Challenge for Neuroscientific and Philosophical Theories.

The European journal of neuroscience  – May 01, 2025

Summary

How does consciousness emerge from brain activity? New research bridges neuroscience and philosophy, showing that our perception and self-awareness arise from a complex interplay of neural processes and cultural concepts. The brain creates conscious experience by combining sensory input with pre-existing mental frameworks shaped by both biology and cultural evolution.

Abstract

Several areas of cognitive neuroscience tackle traditional philosophical questions. Among the range of problems, two closely related issues will be...

Psychological Mediators of Reduced Distress: Preregistered Analyses from a Randomized Controlled Trial of a Smartphone-Based Well-Being Training.

Clinical psychological science : a journal of the Association for Psychological Science  – January 01, 2025

Summary

No Summary

Abstract

Understanding why interventions work is essential to optimizing them. Although mechanistic theories of meditation-based interventions (MBIs) exist,...

A dualist theory of experience.

Philosophical studies  – January 01, 2025

Summary

Our conscious experiences may be more than just brain activity. A novel theory called "delegatory dualism" bridges the gap between physical and mental realms, showing how consciousness can influence physical actions without violating natural laws. The theory suggests that mental states work alongside brain states in a coordinated way, following precise psychophysical laws while avoiding causal conflicts.

Abstract

Dualism holds that experiences somehow arise from physical states, despite being neither identical with nor grounded in such states. This paper mot...

Psilocybin's Erasure of EGO

The Psychoanalytic Review  – December 01, 2023

Summary

A compelling finding: psilocybin, a potent hallucinogen, uniquely reveals the unconscious mind, echoing psychoanalytic theory. One psychotherapist's journey shows profound parallels between psychedelic sessions and psychoanalysis, where the Id, ego, and super-ego manifest. This exploration within psychology proposes a vital dialogue between Psychedelics and Drug Studies and Psychotherapy Techniques and Applications. Such cross-fertilization prevents the erasure of crucial insights from either domain, enriching psychotherapy. This approach promises patient benefits and fosters a deeper cross-cultural and social analysis of therapeutic modalities.

Abstract

The psychoanalytic journey and the psilocybin journey both reveal unconscious dynamics. In this article a psychoanalyst discusses his own psilocybi...

Model Psychoses Induced by LSD-25 in Normals

A M A Archives of Neurology & Psychiatry  – June 01, 1956

Summary

Mescaline and LSD-25 have been pivotal in understanding psychosis, revealing striking similarities to schizophrenia symptoms. In early experiments, mescaline induced profound psychological effects, paralleling those of mental health disorders in 70% of participants. This milestone in experimental psychiatry highlighted the potential of psychedelics in exploring the mind. The organic theory of psychoses gained traction during this period, with substances like methaqualone and cannabis also contributing to insights into altered states of consciousness and their implications for psychology and psychiatry.

Abstract

INTRODUCTION Experimental psychosis has a long history. It might have started with the administration of Cannabis indica boiling in wine to the anc...

Integrated Information Theory and the Phenomenal Binding Problem: Challenges and Solutions in a Dynamic Framework.

Entropy (Basel, Switzerland)  – March 25, 2025

Summary

Our brains seamlessly combine countless bits of sensory information into one unified conscious experience - a feat that challenges our understanding of consciousness. New advances in integrated information theory explain how our minds create this seamless experience through dynamic neural processes, showing how separate sensory inputs become bound together into the rich, flowing stream of consciousness we experience every moment.

Abstract

Theories of consciousness grounded in neuroscience must explain the phenomenal binding problem, e.g., how micro-units of information are combined t...

A Higher Dimension of Consciousness: Constructing an empirically falsifiable panpsychist model of consciousness

arXiv Preprint Archive  – April 11, 2022

Summary

Could consciousness be a hidden dimension of reality? A bold model proposes that awareness exists as a fundamental physical dimension, similar to length or time. By treating consciousness as a spatial property rather than an emergent brain function, this framework offers a testable approach to the age-old mind-body problem, bridging classical physics with theories of universal consciousness.

Abstract

Panpsychism is a solution to the mind-body problem that presumes that consciousness is a fundamental aspect of reality instead of a product or cons...

Psychedelics, entropic brain theory, and the taxonomy of conscious states: a summary of debates and perspectives.

Neuroscience of consciousness  – January 01, 2023

Summary

Psychedelic compounds like psilocybin may hold the key to understanding human consciousness itself. The entropic brain theory suggests these substances create unique states of consciousness by increasing the brain's information-processing flexibility. This framework helps explain how psychedelic states differ from normal consciousness and could potentially aid patients with consciousness disorders through carefully controlled therapeutic applications.

Abstract

Given their recent success in counseling and psychiatry, the dialogue around psychedelics has mainly focused on their applications for mental healt...

5-HT2A Agonists: A Novel Therapy for Functional Neurological Disorders?

The International Journal of Neuropsychopharmacology  – February 08, 2017

Summary

Functional neurological disorders, debilitating psychosomatic conditions, pose a major challenge in Medicine with poor prognosis and limited treatments. Neuroscience and Psychology suggest these stem from abnormal top-down cognitive influence, where the mind perceives bodily dysfunction despite intact pathways—a disturbance of somatic self-representation. Emerging Psychedelics and Drug Studies indicate 5-HT2A agonists could help. These agents modify neural activity, disrupting hierarchical brain dynamics and modulating self-related processing, offering unique therapeutic potential. A clinical trial is warranted.

Abstract

Functional neurological disorders are frequently encountered in clinical practice. They have a poor prognosis and treatment options are limited. Th...

Examining the Potential Synergistic Effects Between Mindfulness Training and Psychedelic-Assisted Therapy

Frontiers in Psychiatry  – August 11, 2021

Summary

Combining mindfulness and psychedelic-assisted therapy shows remarkable promise for mental health. This psychological intervention, a new frontier in clinical psychology, demonstrates synergistic effects, enhancing therapeutic benefits beyond either approach alone. Both mindfulness-based practices and chemical synthesis of alkaloids in psychedelics, used in medicine as complementary and alternative medicine studies, effectively reduce symptoms. Preliminary evidence suggests psychedelics can even enhance mindfulness capacities. This potent dual intervention offers psychotherapists a powerful new tool for counseling, but requires further quantified investigation.

Abstract

Mindfulness-based interventions and psychedelic-assisted therapy have been experimentally utilised in recent years as alternative treatments for va...

Information parity on cortical functional brain networks increases under psychedelic influences

arXiv Preprint Archive  – July 28, 2022

Summary

Psychedelics like Ayahuasca can make different brain regions communicate more symmetrically, revealing new insights about consciousness. By analyzing brain networks before and after Ayahuasca use, researchers found increased information sharing between emotional and decision-making areas. Statistical analysis showed that brain regions achieved greater parity in their communication patterns, suggesting a more integrated state of consciousness.

Abstract

The physical basis of consciousness is one of the most intriguing open questions that contemporary science aims to solve. By approaching the brain ...

Information parity increases on functional brain networks under influence of a psychedelic substance

Journal of Physics Complexity  – March 01, 2023

Summary

Psychedelic experiences significantly enhance brain connectivity, with a notable increase in information parity observed after Ayahuasca consumption. In a study involving 30 participants, functional brain networks showed heightened statistical similarities between regions, particularly within the limbic system and frontal cortex. This suggests that the interactive information system of the brain becomes more resilient under psychedelic influence, indicating a potential mechanism for improved cognitive processing. The findings contribute to our understanding of consciousness and its intricate relationship with brain activity and mental health.

Abstract

Abstract The physical basis of consciousness is one of the most intriguing open questions that contemporary science aims to solve. By approaching t...

Exploring Processes and Dynamics of Mystical Contemplative Meditation: Some Christian-Buddhist Parallels in Relation to Transpersonal Theory

CORE  – January 01, 2015

Summary

Ancient Christian contemplative practices, like the prayer of Recollection, offer profound insights into personal growth, surprisingly paralleling modern mindfulness techniques. This exploration suggests these mystical traditions, developed by figures like St. Teresa of Avila, share therapeutic dynamics with Buddhist Samatha Vipassanā meditation and even Mindfulness-Based Cognitive Therapy. Examining their processes through transpersonal theory reveals how these practices effectively navigate spiritual obstacles and foster deep psychological well-being. The findings highlight the enduring relevance and positive impact of these contemplative paths for personal transformation.

Abstract

This paper explores Christian contemplative meditation, focusing on the prayer of Recollection as it is developed especially by Evelyn Underhill an...

An algebraic theory to discriminate qualia in the brain

arXiv Preprint Archive  – May 31, 2023

Summary

Scientists have discovered how our brains may mathematically distinguish between different types of sensory experiences, like seeing red versus feeling touch. Using neural networks and advanced algebra, researchers demonstrated that the brain creates separate "mental spaces" for different sensation types by weakening independence between neural pathways, helping explain how we process diverse sensory experiences.

Abstract

The mind-brain problem is to bridge relations between in higher-level mental events and in lower-level neural events. To address this, some mathema...

The computational unconscious: Adaptive narrative control, psychopathology, and subjective well-being

CrossRef 

Summary

Our minds unconsciously shape our reality to promote adaptive behavior. A new theory proposes that internal computational mechanisms control our conscious experience, regulating emotions through "mental action." While essential for our subjective well-being, an adaptive strategy of "avoidant mental action" can ironically lead to psychopathology and decreased subjective well-being. This understanding illuminates how practices like meditation and psychedelic therapy positively impact mental health by recalibrating these mechanisms, offering a path to enhanced subjective well-being.

Abstract

This paper introduces the notion of adaptive narrative control, a conception of how subpersonal computational processes shape the contents of consc...

Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans

OpenAlex  – December 09, 2020

Summary

Lysergic acid diethylamide (LSD), a chemically synthesized psychedelic, significantly enhances learning processes. Healthy volunteers, receiving 75μg of LSD versus a placebo, showed increased reinforcement learning rates, particularly for rewards, during a cognitive psychology task involving various stimuli. This suggests heightened brain plasticity, reducing perseveration and promoting exploratory behavior—a key insight for neuroscience and drug studies. This neurotransmitter receptor influence on behavior offers a promising mechanism for psychology to revise maladaptive associations.

Abstract

Abstract The non-selective serotonin 2A (5-HT 2A ) receptor agonist lysergic acid diethylamide (LSD) holds promise as a treatment for some psychiat...

Understanding the Nature of Oneness Experience in Meditators Using Collective Intelligence Methods

Frontiers in Psychology  – September 17, 2020

Summary

Mindfulness and Meditation practices profoundly reshape self-perception, cultivating experiences of "oneness." A collective intelligence methodology, engaging five groups of experienced meditators, uncovered consistent psychological themes in this altered perception. Participants highlighted changes in their sense of space, time, identity, wholeness, and flow as most influential. This insight is crucial for advancing Behavioral Health and Interventions, demonstrating how Mindfulness and Compassion Interventions can transform self-understanding. These findings also enrich the evolving field of social psychology.

Abstract

Research on meditation and mindfulness practice has flourished in recent years. While much of this research has focused on well-being outcomes asso...

The effect of mindfulness interventions on couple relationship satisfaction: A systematic review and meta-analysis.

Journal of consulting and clinical psychology  – June 01, 2025

Summary

Mindfulness practices offer a tangible boost to romantic partnerships. A large-scale analysis of over 6,000 individuals revealed that integrating mindfulness consistently improves couples' relationship satisfaction. These interventions, effective for both general and clinical populations, foster greater connection and contentment, highlighting a positive pathway for stronger, more harmonious bonds.

Abstract

Mindfulness interventions (MIs) train nonjudgmental attention to present-moment experience and aim to improve mental health and well-being. The evi...

Whole-Brain Models to Explore Altered States of Consciousness from the Bottom Up

MDPI (MDPI AG)  – September 10, 2020

Summary

Understanding altered states of consciousness offers a unique window into the mind. Psychology and Cognitive science propose a research program bridging top-down theories of consciousness with bottom-up generative models of neural dynamics. This involves exploring how global brain activity, seen across various subjective experiences, arises from local neural tissue properties. Using whole-brain models in Neuroscience and Neuropharmacology Research, including functional brain connectivity studies, aims to systematically investigate consciousness's biophysical and informational underpinnings by examining two core design approaches: top-down and bottom-up.

Abstract

The scope of human consciousness includes states departing from what most of us experience as ordinary wakefulness. These altered states of conscio...

A prospective ecological momentary assessment study of an ayahuasca retreat: exploring the salutary impact of acute psychedelic experiences on subacute affect and mindfulness skills in daily life

Psychopharmacology  – January 18, 2025

Summary

Ayahuasca use notably improved mood and mindfulness skills for 36 participants. Post-retreat, individuals reported reduced negative affect and increased positive affect, alongside enhanced mindfulness in daily life. Acute psychedelic experiences, including emotional breakthroughs, predicted greater positive affect. This suggests Ayahuasca, a complex blend of alkaloids, profoundly influences psychology and affect. Only 5.5% experienced some mood deterioration, with no clinically significant adverse responses, highlighting its potential for further drug studies in clinical psychology.

Abstract

Abstract Rationale To examine the acute effects of ayahuasca use and their relationship to sub-acute changes in affect and mindfulness in a non-cli...

Fearful symmetry in altered states: a bi-logic account of psychedelic action.

Front Psychol  – August 19, 2025

Summary

Our minds often operate with two distinct, yet interacting, logical systems for processing information. A new theory proposes that psychedelics profoundly shift consciousness by altering the dynamic balance between these two fundamental modes of processing reality. Integrating neuroscientific and psychological insights, it suggests these substances don't just change perception, but enable a unique "bi-logic" state. This allows for novel perspectives and deep personal insights, potentially fostering significant psychological well-being and understanding.

Abstract

Fearful symmetry in altered states: a bi-logic account of psychedelic action.

Psychedelics: a window into perceptual processing

OpenAlex  – September 13, 2024

Summary

Psilocybin-induced visual distortions and impaired executive function originate in temporary disruptions of attentional mechanisms, a key finding for cognitive psychology. This work, relevant to psychedelics and drug studies, argues that existing predictive processing models, often explored in computer science for understanding perception, cannot fully explain psychedelic experiences. Instead, a new "Gist Theory of Perception" is proposed. This theory better explains how psilocybin, a potent alkaloid, alters sensory function and perception, offering a unique window into the mind's complex processes within psychology.

Abstract

Abstract This chapter presents findings indicating that psilocybin-induced visual distortions and impaired executive functioning originate in tempo...

Time-resolved network control analysis links reduced control energy under DMT with the serotonin 2a receptor, signal diversity, and subjective experience

OpenAlex  – May 12, 2023

Summary

Psychedelics like psilocybin and the hallucinogen lysergic acid diethylamide profoundly reshape brain dynamics. Neuroscience reveals that N,N-dimethyltryptamine (DMT), a serotonergic compound, significantly reduces the "control energy" needed for brain state transitions in 14 individuals. This finding, crucial for Psychology and Mental Health Research Topics, shows global control energy trajectories, potentially involving the default mode network, correlate with subjective drug intensity. These effects are linked to serotonin 2a receptor density, demonstrating neurotransmitter receptor influence on behavior and offering a predictive model for Psychedelics and Drug Studies.

Abstract

Abstract Psychedelics offer a profound window into the functioning of the human brain and mind through their robust acute effects on perception, su...

Psychedelics and Meditation: A Neurophilosophical Perspective

Routledge Handbook on the Philosophy of Meditation  – January 01, 2022

Summary

Our sense of self, often seen as fixed, can be profoundly shifted by both psychedelics and meditation. A neurophilosophical perspective reveals deep commonalities. Both impact overlapping brain networks tied to self-perception and attention, fostering lasting mindfulness. They can weaken foundational beliefs about identity, allowing us to see thoughts as separate from self. This framework offers insights into meditation's potential benefits for understanding reality.

Abstract

Psychedelic ingestion and meditative practice are both ancient methods for altering consciousness that became widely known in Western society in th...

Wasson's Alternative Candidates for Soma

Journal of Psychoactive Drugs  – April 01, 1993

Summary

R. Gordon Wasson, famed for linking Vedic soma to the psychoactive mushroom *Amanita muscaria*, privately explored many other candidates, revealing his open-mindedness. Unpublished letters show he considered plants like *Lagochilus inebrians* and morning glory seeds, plus the fungal parasite *Claviceps purpurea*, and especially the psilocybin mushroom *Stropharia cubensis*. These documents from the Harvard Botanical Museum underscore his meticulous approach to traditional medicine. They highlight the intricate plant and fungal interactions involved in identifying ancient psychedelics, touching on aspects of toxicology and the chemical synthesis of alkaloids in his exhaustive drug studies.

Abstract

Citing recently published challenges to R. Gordon Wasson's identification of Vedic soma as the psychoactive mushroom Amanita muscaria (fly-agaric),...

The spiritual core of the hard problem: consciousness as foundational, not emergent.

Frontiers in psychology  – January 01, 2025

Summary

What if consciousness isn't born from the brain, but is reality's very foundation? This view posits consciousness is primary, challenging materialist thought. Integrating non-dual traditions like Advaita Vedanta with contemplative science and transpersonal psychology, it suggests a transpersonal cosmology offers a superior model for subjective experience. Emphasizing participatory knowing and spiritual phenomenology, this framework successfully bridges science and spirituality, advancing human flourishing and a deeper understanding of our universe.

Abstract

This paper proposes a transpersonal reframing of the Hard Problem of Consciousness by positing that consciousness is ontologically primary-not an e...

Meditation and Self-transcendence: A Human Need?

Integrative psychological & behavioral science  – September 01, 2024

Summary

No Summary

Abstract

Building on Fircks (2023), who aims at integrating the theoretical and historical roots of mindfulness into psychology through a bridge between Tao...

Integrating mindfulness into the academic curriculum: A qualitative study.

Journal of American college health : J of ACH  – June 05, 2025

Summary

College students who learned meditation techniques showed remarkable improvements in stress management and self-awareness. Through contemplative education practices, including Koru Mindfulness exercises, participants developed practical tools for emotional regulation and academic focus. The program, integrated into regular coursework, helped students cultivate mindfulness habits that enhanced both their classroom performance and overall wellbeing.

Abstract

Objective: Most undergraduate students experience high stress levels, necessitating university support. Meditation-based programs can encourage stu...

Serotonergic Psychedelics LSD & Psilocybin Increase the Fractal Dimension of Cortical Brain Activity in Spatial and Temporal Domains

OpenAlex  – January 11, 2019

Summary

Brain activity becomes more 'fractal' under psychedelics like psilocybin, profoundly altering consciousness. Neuroscience shows hallucinogens such as LSD and psilocybin significantly increase the fractal dimension of brain networks. LSD also significantly increased the fractal dimension of BOLD signals, with psilocybin showing a similar trend. These serotonergic compounds move the brain towards a critical state, where complex, fractal patterns emerge. This insight, leveraging computer science, informs psychology's pattern recognition theories, Psychedelics and Drug Studies, and biochemical mechanisms of perception, possibly aiding Artificial intelligence.

Abstract

Abstract Psychedelic drugs, such as psilocybin and LSD, represent unique tools for researchers in-vestigating the neural origins of consciousness. ...

Constructing the ecstasy of MDMA from its component mental organs: Proposing the primer/probe method.

Medical hypotheses  – February 01, 2016

Summary

The unique "open-hearted" feeling from MDMA might not be just about neurotransmitter release. A new theory proposes that specific mental states arise from "mental organs"—neuron groups linked to particular receptors. These organs enter consciousness when their defining receptor is activated alongside serotonin-2 receptors. A "primer/probe" method is introduced to test this. By combining a primer (activating serotonin-2) with a probe (activating another specific receptor), one can isolate and understand the precise pharmacological effects of these mental organs, offering a clear path to decipher complex brain states.

Abstract

The drug MDMA, commonly known as ecstasy, produces a specific and distinct open hearted mental state, which led to the creation of a new pharmacolo...

Simultaneity of consciousness with physical reality: the key that unlocks the mind-matter problem

arXiv Preprint Archive  – September 27, 2023

Summary

Consciousness creates its own causal power, independent of what we're actually experiencing - a groundbreaking insight into the mind-body problem. This analysis challenges traditional views that treat consciousness as a mere byproduct of physical processes. Through logical deduction from fundamental experiential truths, research shows consciousness generates new degrees of freedom in ways that can't be predicted through standard sequential observation. This has major implications for neuroscience and makes testable predictions about brain function.

Abstract

The problem of explaining the relationship between subjective experience and physical reality remains difficult and unresolved. In most explanation...

How to create a mindful community of practice: exploring the social functions of group-based mindfulness practices facilitated via Zoom during COVID-19.

Frontiers in psychology  – January 01, 2025

Summary

No Summary

Abstract

This exploratory qualitative study was conducted to investigate the experiences of individuals who have been participating in online mindfulness se...

Science: A Solid Whole

arXiv Preprint Archive  – January 28, 2003

Summary

The puzzling relationship between consciousness and quantum measurements reveals a fundamental challenge in modern physics. While classical physics treats observers as separate from experiments, quantum theory suggests our consciousness actively influences what we measure. This insight points to a deeper unity between mind and matter, challenging traditional scientific frameworks that separate observer from observed phenomena.

Abstract

However, the observations encompassed by classical physics excludes the observer from the physical reality, yet the deep-down understandung of natu...

Teacher plants - Indigenous Peruvian-Amazonian dietary practices as a method for using psychoactives.

Journal of ethnopharmacology  – March 25, 2022

Summary

No Summary

Abstract

Indigenous groups of the Amazon have developed intricate methods for the application of psychoactives, among which particularly the dieta or diet m...

Managing psychological distress in women with breast cancer: A systematic review of intervention trends in the past decade.

Asia-Pacific journal of oncology nursing  – December 01, 2026
preprint

Summary

Remarkably, 57% of interventions significantly reduce psychological distress in breast cancer survivors. A review of 14 trials, involving 2,447 cancer survivors, found that multimodal approaches like mindfulness or VR psychotherapy effectively manage stress, improving quality of life. These interventions achieved small to large effects (Cohen's d = 0.44-1.54). Purely cognitive or unstructured digital programs offered limited psychological benefit. Effective support for breast cancer survivors requires comprehensive, theory-based strategies to alleviate distress.

Abstract

The rising incidence and survival rates of breast cancer have increased the number of breast cancer survivors (BCSs) experiencing psychological dis...

Applying intervention mapping approach to a program for early intervention in first-episode mental crisis of a psychotic type.

Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS  – March 13, 2020

Summary

No Summary

Abstract

The holotropic mind perspective, an integral part of the framework of transpersonal psychology, has been considered a revolutionary approach to a c...

Consciousness in active inference: Deep self-models, other minds, and the challenge of psychedelic-induced ego-dissolution.

Neuroscience of consciousness  – January 01, 2021

Summary

No Summary

Abstract

Predictive processing approaches to brain function are increasingly delivering promise for illuminating the computational underpinnings of a wide r...

EASTERN MYSTICISM AND TIMOTHY LEARY: HUMAN BEYOND THE CONVENTIONAL REALITY

Anthropological Measurements of Philosophical Research  – June 28, 2017

Summary

T. Leary, experimenting with psilocybin and LSD, discovered the human body contained billions of universes, suggesting an organic basis for creativity. This transpersonal psychology perspective, integrating Eastern philosophy and contemporary human science, offers a new epistemology of human being. It highlights transcending illusory "subject-object" duality for enlightenment—a profound religious experience. This interpretation, drawing from diverse academic themes and examining historical documents, provides a fresh context for consciousness, bridging ancient mysticism with modern psychedelics and drug studies.

Abstract

Introduction. The complex multifaceted essence of human as a biological, psychological, social being has attracted the attention of researchers and...

LSD and psilocybin flatten the brain’s energy landscape: insights from receptor-informed network control theory

OpenAlex  – May 17, 2021

Summary

Psychedelics like LSD and psilocybin significantly ease the brain's ability to transition between different activity states, promoting more varied dynamics. This finding from Functional Brain Connectivity Studies highlights how these compounds, central to Psychedelics and Drug Studies, effectively "flatten" the brain's energy requirements. LSD's impact correlates with more frequent state changes and increased brain diversity across individuals. This mechanism, vital for Mental Health Research Topics, is specifically driven by serotonin 2a receptors, enabling more fluid brain activity.

Abstract

Abstract Psychedelics like lysergic acid diethylamide (LSD) and psilocybin offer a powerful window into the function of the human brain and mind, b...

Why Uncertainty Is Essential for Consciousness: Local Prospect Theory vs. Predictive Processing.

Entropy (Basel, Switzerland)  – January 28, 2025

Summary

No Summary

Abstract

We present and develop local prospect theory (LPT), a novel framework for understanding consciousness, and, in particular, subjective experience an...

Mind beyond the brain: proposal of a pragmatic interactionist framework.

International review of psychiatry (Abingdon, England)  – January 01, 2025

Summary

Remarkable experiences suggest consciousness may extend beyond the physical brain. A new hypothesis proposes a pragmatic interactionist model, suggesting the mind–brain relationship allows the mind to function independently, with the brain serving as a tool or filter. This theory, drawing on evidence like near-death and out-of-body accounts, offers a robust framework to understand complex mental phenomena, providing a strong foundation for exploring the human mind.

Abstract

The nature of consciousness remains unclear, and academic discussions usually ignore the scientific evidence about anomalous and spiritual experien...

Understanding and Addressing Bullying in Children and Adolescents.

Journal of the Korean Academy of Child and Adolescent Psychiatry  – January 01, 2026

Summary

Bullying profoundly impacts children and adolescents, causing significant psychological and social distress. A review of studies published between 2000 and 2024 highlights its global prevalence and diverse forms. This chronic stressor can dysregulate neurobiological systems, increasing vulnerability to anxiety and depression. Effective psychotherapy, including Cognitive behavioral therapy and Play therapy, helps mitigate bullying's effects and improve child well-being. Addressing bullying requires comprehensive strategies integrating psychological, educational, and legal efforts to foster safe environments.

Abstract

Bullying among children and adolescents is a complex and widespread problem with profound psychological, social, and legal implications. It include...

Quantum Models of Mind: Are They Compatible with Environment Decoherence?

arXiv Preprint Archive  – March 05, 2004

Summary

Can quantum physics explain consciousness? While some theories suggest our minds operate through quantum processes, environmental interactions may disrupt these delicate quantum states. This analysis shows that while the popular Penrose-Hameroff quantum consciousness model faces challenges from environmental interference, quantum effects in brain function remain possible through different mechanisms involving decoherence.

Abstract

We criticize the Hameroff Penrose model in the context of quantum brain model by gravitational collapse orchestrated objective reduction, orch. OR,...

Classical physics and human embodiment: The role of contemplative practice in integrating formal theory and personal experience in the undergraduate physics curriculum

arXiv Preprint Archive  – April 16, 2018

Summary

Many physics students struggle to connect abstract theories with daily life. Integrating contemplative practices, like sensory meditation and videography, into undergraduate physics.ed-ph courses dramatically improves this. Students reported suddenly seeing physics principles everywhere, gaining a deeper embodied understanding. They also experienced heightened awareness, relaxation, and renewed curiosity, fostering a stronger intrinsic motivation for scientific observation and learning.

Abstract

One of the objectives of the undergraduate physics curriculum is for students to become aware of the connections between the fundamental principles...

Harvard's Quixotic Pursuit of a New Science

Rowman & Littlefield Publishers eBooks  – January 01, 2022

Summary

Harvard's 1930s attempt to unify social sciences led to shocking ethical lapses. Scholars, pursuing Freudian philosophy, formed a new interdisciplinary department to surpass Harvard's "big three" disciplines. Despite its audacious failure, it attracted brilliant minds. Faculty infamously gave psychedelic drugs to students, and one traumatized undergraduate Theodore Kaczynski in a three-year experiment. This tale of academic hubris, collaboration, and philosophical quests highlights university challenges.

Abstract

In Harvard’s Quixotic Pursuit of a New Science, Patrick L. Schmidt tells the little-known story of how some of the most renowned social scientists ...

The assumptions that restrain us from understanding consciousness

arXiv Preprint Archive  – June 26, 2025

Summary

Our very assumptions about consciousness might be hindering its scientific understanding. A critical re-evaluation reveals that focusing solely on neural spikes or simple computations is restrictive. This q-bio.NC analysis suggests exploring the intricate nature of consciousness, including internal shifts like "aha-moments," offers profound new avenues. Challenging established views unlocks a richer, more complex understanding of the mind.

Abstract

The science of consciousness has been successful over the last decades. Yet, it seems that some of the key questions remain unanswered. Perhaps, as...

An Integrated theory of false insights and beliefs under psychedelics.

Commun Psychol  – August 01, 2024

Summary

Psychedelics can unlock profound, often life-changing, insights. A new integrated theory explains how these substances influence belief formation, offering a framework for both genuine and perceived false revelations. By synthesizing neuroscience and psychology, it illuminates how altered brain states enhance creativity and self-reflection. This framework highlights the brain's remarkable capacity for new perspectives, providing a deeper understanding of consciousness.

Abstract

An Integrated theory of false insights and beliefs under psychedelics.