328 results for "Phenomenology"
Phenomenology and therapeutic potential of patient experiences during oral esketamine treatment for treatment-resistant depression: an interpretative phenomenological study.
Psychopharmacology – July 01, 2023
Summary
Patients receiving oral esketamine for severe depression report profound experiences of detachment and mystical encounters, offering new hope for those who haven't responded to conventional treatments. Through in-depth interviews with 17 patients, researchers found that while the medication produced varying effects, many experienced increased openness and spiritual connections, alongside temporary relief from negative thought patterns. Despite some challenging moments during treatment, patients reported meaningful shifts in perspective and emotional breakthroughs.
Abstract
Ketamine and its enantiomers are widely researched and increasingly used to treat mental disorders, especially treatment-resistant depression. The ...
Modelling phenomenological differences in aetiologically distinct visual hallucinations using deep neural networks
Frontiers in Human Neuroscience – January 03, 2024
Summary
Visual hallucinations, despite a shared lack of sensory input, manifest profoundly different perceptual characteristics depending on their origin. A novel computational neuroscience approach, leveraging deep neural networks, explored these distinct experiences across three groups: individuals with neurodegenerative conditions (like Parkinson's disease or Lewy body dementia), visual loss, and those experiencing psychedelic effects. This cognitive science method identified three key phenomenological dimensions—realism, spontaneity, and complexity—that distinguish these hallucinations. By tuning model parameters, characteristic synthetic visual hallucinations were generated, accurately reflecting each group's unique perception.
Abstract
Visual hallucinations (VHs) are perceptions of objects or events in the absence of the sensory stimulation that would normally support such percept...
Phenomenology of Psychedelic Experiences and Psychedelic-Associated Distressing Effects: Quantifying Subjective Experiences.
Current topics in behavioral neurosciences – December 31, 2024
Summary
No Summary
Abstract
The range of phenomena that can be induced by psychedelic substances is broad and variable, including effects on perception, cognition, and emotion...
The French crisis: Rethinking the phenomenology of quantum mechanics.
Studies in history and philosophy of science – June 13, 2025
Summary
Edmund Husserl's phenomenology offers a fresh perspective on quantum theory's foundations. His analysis of mathematization in physics reveals how abstract mathematical concepts shape our understanding of reality. The work shows how quantum mechanics bridges pure mathematics and lived experience, addressing concerns raised in "The Crisis of European Sciences" about the disconnect between scientific models and everyday reality. The philosophy of physics gains new insights through this phenomenological lens.
Abstract
In his book, A Phenomenological Approach to Quantum Mechanics: Cutting the Chain of Correlations, Steven French argues that quantum mechanics, unde...
Breaking through the doors of perception, consciousness, and existence: to what extent does psychedelic phenomenology ontologically depend on external factors?
Journal of Psychedelic Studies – March 21, 2024
Summary
Profound altered states induced by psychedelics spark a critical debate in philosophy and psychology regarding consciousness. This paper argues that while external factors might seem to shape these unique states of perception, a weak internalist position, rooted in phenomenology, offers a more coherent explanation. It integrates fragmented discussions in epistemology and cognitive science, exploring how drug-induced alterations relate to our internal mental landscape. Ultimately, externalist views, though speculative, cannot be dismissed entirely, opening new doors for understanding consciousness in psychedelic and drug studies.
Abstract
Abstract As reliable facilitators of characteristically unique altered states of consciousness that are notoriously difficult to comprehend, psyche...
Self-Boundary Dissolution in Meditation: A Phenomenological Investigation.
Brain sciences – June 21, 2021
Summary
No Summary
Abstract
A fundamental aspect of the sense of self is its pre-reflective dimension specifying the self as a bounded and embodied knower and agent. Being a c...
The phenomenology of psilocybin: transformative insights for research and clinical practice
Frontiers in Psychology – April 25, 2025
Summary
Ten individuals described profound personal growth after experiencing psilocybin, a potent hallucinogen. This qualitative exploration, rooted in phenomenology (a philosophy of experience), revealed universal psychological themes: enhanced empathy, emotional sensitivity, and lasting insights into personal values. Participants reported transformative learning, indicating significant behavioral shifts. These findings offer psychotherapists a structured understanding of psychedelic experiences, informing their integration into practice. Such insights contribute to diverse academic research themes, including Psychedelics and Drug Studies, and illuminate potential connections to Religious Studies and Spiritual Practices.
Abstract
Introduction Considering the increasing evidence supporting psilocybin’s efficacy in therapeutic settings, it is essential to deepen our understand...
Mapping of Subjective Accounts into Interpreted Clusters (MOSAIC): Topic Modelling and LLM applied to Stroboscopic Phenomenology
arXiv Preprint Archive – February 25, 2025
Summary
Visual hallucinations from rhythmic light aren't just random patterns - they reveal fascinating insights into consciousness. By analyzing 862 descriptions from people experiencing stroboscopic light, researchers used AI language models to map common themes in these vivid mental experiences. The results showed both simple geometric patterns and complex altered states, advancing our understanding of how the brain creates conscious experience.
Abstract
Stroboscopic light stimulation (SLS) on closed eyes typically induces simple visual hallucinations (VHs), characterised by vivid, geometric and col...
The Spiral of Attention, Arousal, and Release: A Comparative Phenomenology of Jhāna Meditation and Speaking in Tongues.
American journal of human biology : the official journal of the Human Biology Council – December 01, 2024
Summary
No Summary
Abstract
Buddhist Jhāna meditation and the Christian practice of speaking in tongues appear wildly distinct. These spiritual techniques differ in their ethi...
A phenomenological analysis of the subjective experience elicited by ibogaine in the context of a drug dependence treatment
Journal of Psychedelic Studies – August 29, 2017
Summary
A compelling finding from drug studies reveals ibogaine, a potent hallucinogen, can trigger challenging psychological experiences. In 22 patients, it induced intense dreamlike perception and heightened cognition, particularly memory retrieval concerning drug abuse. Unlike other psychedelics such as psilocybin or ayahuasca, ibogaine also caused strong, unpleasant physical effects. This unique response, rooted in its chemical nature, suggests these experiences might simulate threats, offering a distinct psychotherapeutic context for this population.
Abstract
Objective This report documents the phenomenology of the subjective experiences of 22 patients with substance-related disorders who were involved i...
Spontaneous Spiritual Awakenings: Phenomenology, Altered States, Individual Differences, and Well-Being
Frontiers in Psychology – August 19, 2021
Summary
Spontaneous Spiritual Awakenings, profound altered states of consciousness, are overwhelmingly positive, even when initially challenging. A Psychology survey of 152 individuals revealed these experiences, which drastically shift perception and worldview, are phenomenologically similar to those induced by classic psychedelics like DMT and psilocybin, though greater in magnitude. Personality traits, such as absorption, predict these events. This work, relevant to Phenomenology, Psychedelics and Drug Studies, and even Paranormal Experiences, illuminates how consciousness can profoundly transform individual well-being and development.
Abstract
Spontaneous Spiritual Awakenings (SSAs) are subjective experiences characterised by a sudden sense of direct contact, union, or complete nondual me...
When pain overwhelms the self: A phenomenological study of a new mode of suffering, based on adults' recollections of their worst pain episodes.
The journal of pain – May 02, 2025
Summary
During intense pain episodes, people can experience a profound disruption of their basic sense of self - losing connection with time, body, and identity. Through in-depth interviews with chronic pain patients, researchers uncovered how severe pain can create immediate suffering that transcends conscious thought. This qualitative study revealed that overwhelming pain can lead to dissociative states where sufferers feel dehumanized and disconnected from themselves.
Abstract
Suffering is a foundational yet understudied construct within the field of pain. There is general agreement that pain-related suffering involves di...
Participant Reports of Mindfulness, Posttraumatic Growth, and Social Connectedness in Psilocybin-Assisted Group Therapy: An Interpretive Phenomenological Analysis
Journal of Humanistic Psychology – June 12, 2021
Summary
Psilocybin-assisted group psychotherapy profoundly shifted how individuals processed trauma. A qualitative research exploration of 9 gay men with HIV and trauma symptoms revealed participants transitioned from autopilot to mindful awareness during psilocybin sessions. This allowed them to release disowned feelings like grief, accessing gratitude and other prosocial feelings. Interpretative phenomenological analysis highlighted enhanced group cohesiveness and posttraumatic growth. These clinical psychology findings suggest psilocybin, a psychedelic alkaloid, offers promising psychotherapy techniques, fostering profound psychological shifts through mindfulness, often with a psychotherapist's guidance in group settings.
Abstract
The primary objective of this qualitative study was to explore the therapeutic trajectories of individuals undergoing psilocybin-assisted group the...
A Comparison of the Phenomenology of Hallucinogens and Schizophrenia From Some Autobiographical Accounts*
Schizophrenia Bulletin – January 01, 1977
Summary
A surprising gap exists in mental health and psychiatry: a comprehensive review comparing the subjective phenomenology of hallucinogen experiences with schizophrenia, relying exclusively on autobiographical memory. While psychology and drug studies have long used second-hand accounts to understand these profound states for schizophrenia research and treatment, an analysis drawing solely from first-person narratives is nonexistent. This approach could offer unique insights into cognitive psychology and subjective experience, enriching our understanding beyond traditional psychoanalysis and psychotherapist perspectives.
Abstract
Over the years there have been many reviews of the phenomenology of hallucinogens and schizophrenia. The vast majority of these have been written b...
Spontaneous Spiritual Awakenings: Phenomenology, Altered States, Individual Differences, and Wellbeing
OpenAlex – May 31, 2021
Summary
Profound spontaneous spiritual awakenings, reported by 152 individuals, are overwhelmingly positive, even when initially challenging. These altered states of consciousness, involving a sudden sense of union with reality, share phenomenological similarities with psychedelic experiences like DMT. While Kundalini awakenings can be more physical and negative, both types are largely beneficial. Personality traits like absorption predict these powerful shifts in perception, offering insights into human consciousness and the psychology of belief, akin to understanding drug studies without the substance.
Abstract
Spontaneous Spiritual Awakenings (SSAs) are subjective experiences characterised by a sud- den sense of direct contact, union or merging with a per...
Ketamine Psychedelic Psychotherapy: Focus on its Pharmacology, Phenomenology, and Clinical Applications
International Journal of Transpersonal Studies – July 01, 2014
Summary
Ketamine, a powerful dissociative medicine, is transforming psychiatry's approach to major depression. Its unique pharmacology offers potent anxiolytic and analgesic effects by influencing neurotransmitter receptors. Psychotherapists are exploring its use in Psychedelics and Drug Studies, particularly Ketamine Psychedelic Psychotherapy (KPP). An extensive review of literature details KPP's clinical applications, exploring the phenomenology of transpersonal experiences to guide treatment, drawing on Psychology and Neuroscience. It also highlights potential risks, underscoring its role in modern medicine.
Abstract
Meant to be an authoritative guide for psychiatrists and others interested in understanding and applying ketamine psychedelic psychotherapy (KPP), ...
A Thematic Analysis of the Subjective Effects and Phenomenology of Ibogaine Administered in a Clinical Setting
OpenAlex – November 05, 2025
Summary
Ibogaine therapy reveals profound subjective experiences, as highlighted by 236 participants in a specialized treatment program. Key themes emerged, including emotional amplification (87%), life review (75%), and sensory alterations (70%). Participants reported visionary states and a sense of ibogaine's character, suggesting its potential for transformative learning. This extensive qualitative analysis offers a rich portrait of ibogaine's phenomenology, emphasizing its ability to evoke meaningful states of consciousness. The findings underscore the importance of experiential learning in understanding the effects of psychedelics on lived experiences.
Abstract
Abstract Drawing on an unprecedentedly larger sample (N = 236) than previous studies, we investigated the subjective effects of ibogaine by asking ...
Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology.
Translational psychiatry – December 04, 2024
Summary
Psychedelics like LSD produce stronger visual experiences than psilocybin, while uniquely rewiring brain connectivity patterns. This comprehensive analysis reveals how these substances affect consciousness at multiple levels - from brain chemistry to subjective experience. Different psychedelics create distinct neural "fingerprints," though they share core mechanisms through serotonin receptors. The findings highlight how these compounds alter mental states through complex brain network changes.
Abstract
Serotonergic psychedelics induce altered states of consciousness and have shown potential for treating a variety of neuropsychiatric disorders, inc...
Inner Light and the Eyes of the Soul: A Phenomenological Analysis of Teresa of Ávila's Visions through the Lens of Phosphene Taxonomy
PsyArXiv Preprints – June 16, 2025
Summary
Mystics across cultures, from Teresa of Ávila to Tibetan sage Milarepa, have reported seeing intense inner light during deep meditation. New analysis reveals these visions match patterns of phosphenes—natural light phenomena in our visual system. By comparing Teresa's detailed accounts with those of Hildegard of Bingen and Longchenpa, researchers found that mystical luminosity experiences follow consistent stages during contemplation and altered states of consciousness, suggesting a universal basis for spiritual light visions.
Abstract
This paper examines the visionary experiences of Saint Teresa of Ávila (1515–1582) as described in The Life of Teresa of Jesus, through the lens of...
Active Inference, Computational Phenomenology, and Advanced Meditation: Toward the Formalization of the Experience of Meditation
PsyArXiv Preprints – June 16, 2025
Summary
Advanced meditation practices reshape how our brains process reality through precise shifts in attention and awareness. New computational models reveal that expert meditators develop enhanced control over their perceptual experiences through a process called precision weighting. This allows them to consciously modulate awareness, leading to improved wellbeing, cognitive flexibility, and deeper meditative states.
Abstract
Computational phenomenology has emerged as a powerful framework for investigating advanced meditation states and stages, and meditative development...
Synergistic, Multi-level Understanding of Psychedelics: Three Systematic Reviews and Meta-analyses of Their Pharmacology, Neuroimaging and Phenomenology
OpenAlex – October 07, 2023
Summary
LSD induces more profound visionary experiences than psilocybin, a key finding from a meta-analysis exploring how these serotonergic hallucinogens alter consciousness. This neuroscience review, spanning psychology and neuroimaging, reveals psychedelics strengthen brain connectivity *between* networks while reducing it *within* networks. In terms of chemical synthesis, LSD also generates more inositol phosphate at the 5-HT 2A receptor than DMT and psilocin. This integrated understanding of neurotransmitter receptor influence on behavior offers insights into potential addiction treatments, advancing Psychedelics and Drug Studies.
Abstract
Abstract Serotonergic psychedelics induce altered states of consciousness and have shown potential for treating a variety of neuropsychiatric disor...
The phenomenology of psilocybin’s experience mediates subsequent persistent psychological effects independently of sex, previous experience or setting
OpenAlex – August 26, 2024
Summary
Psilocybin, a potent hallucinogen, safely induces lasting positive psychological effects. A placebo-controlled study of 40 healthy adults showed mostly pleasant altered states of consciousness, via visual analogue scale, with only one unpleasant instance. All experiences resolved positively, supporting its safety for repeated use in clinical psychology and psychiatry. This underscores Psychedelics and Drug Studies, revealing how chemical synthesis and alkaloids influence neurotransmitter receptor influence on behavior. Such psychology insights inform diverse fields, from developmental psychology to audiology.
Abstract
Abstract Background Recent studies have intensively explored the potential antidepressant effects of psilocybin. However, important variables such ...
Integrated Phenomenology and Brain Connectivity Demonstrate Changes in Nonlinear Processing in Jhana Advanced Meditation.
Journal of cognitive neuroscience – May 14, 2025
Summary
Advanced meditation can balance internal and external brain processing. Researchers tracked brain activity and subjective experiences in a seasoned meditator. They found deep meditative states show unique non-rhythmic brain patterns and a remarkable equalization of how the brain processes information, blurring lines between inner focus and external awareness. This reveals new insights into profound conscious states.
Abstract
We present a neurophenomenological case study investigating distinct neural connectivity regimes during an advanced concentrative absorption medita...
Salvia divinorum use and phenomenology: results from an online survey.
Journal of psychopharmacology (Oxford, England) – November 01, 2011
Summary
Many users of the hallucinogenic plant *Salvia divinorum* report few troubling adverse effects. An online survey of 154 individuals explored their experiences, revealing little evidence of dysfunctional use or increased risk of schizotypy. Users described unique mixed hallucinogenic and dissociative effects, distinguishing it from other substances. Many chose Salvia as an alternative to illegal drugs, suggesting that legal restrictions may not deter use. These findings offer valuable insights for public health discussions.
Abstract
Salvia divinorum is a hallucinogenic plant with ethnopharmacological and recreational uses. It differs from classic serotonergic hallucinogens such...
Advanced concentrative absorption meditation reorganizes functional connectivity gradients of the brain: 7T MRI and phenomenology case study of jhana meditation.
Cerebral cortex (New York, N.Y. : 1991) – April 01, 2025
Summary
No Summary
Abstract
There is growing scientific interest in advanced meditation, and particularly the Theravada Buddhist advanced concentrative absorption meditation k...
Phenomenology of auto-induced cognitive trance using text mining: a prospective and exploratory group study.
Neuroscience of consciousness – January 01, 2024
Summary
No Summary
Abstract
Auto-induced cognitive trance (AICT) is a modified state of consciousness derived from shamanic tradition that can be practised by individuals afte...
Phenomenology and content of the inhaled N, N-dimethyltryptamine (N, N-DMT) experience.
Scientific reports – May 24, 2022
Summary
No Summary
Abstract
Understanding the phenomenology and content of the inhaled N, N, dimethyltryptamine (N, N-DMT) experience is critical to facilitate and support ong...
Phenomenological characteristics of auto-induced cognitive trance and Mahorikatan® trance.
Neuroscience of consciousness – January 01, 2024
Summary
No Summary
Abstract
Trance states include various practices characterized by a modulation of consciousness, but with their own specific characteristics and induction t...
Phenomenology and Content of the Inhaled N, N-Dimethyltryptamine (N, N-DMT) Experience
Research Square – April 28, 2022
Summary
Many individuals describe encountering "entities" during experiences with inhaled N, N-DMT. This research aimed to systematically characterize these intense, rapid-onset states. Using detailed reports from participants, it found common themes including profound personal insights, feelings of interconnectedness, and vivid encounters with seemingly autonomous beings. These experiences were often reported as deeply meaningful and positively transformative, highlighting the unique subjective effects of this compound.
Abstract
Phenomenology and Content of the Inhaled N, N-Dimethyltryptamine (N, N-DMT) Experience
Patient Experiences of Psilocybin-Assisted Psychotherapy: An Interpretative Phenomenological Analysis
Journal of Humanistic Psychology – April 28, 2017
Summary
Psilocybin-assisted psychotherapy profoundly alleviates psychological distress. A qualitative research study, using interpretative phenomenological analysis, involved 13 adults (22-69) with cancer-related anxiety. Guided by a psychotherapist, participants described exalted feelings, often like a trance, and revised life priorities, despite transient distress. This work, relevant to Psychology, Complementary and Alternative Medicine Studies, and Drug Studies, explores Psilocybin’s transformative potential. As a psychedelic compound, its effects, rooted in chemical synthesis and alkaloids, offer new avenues for well-being.
Abstract
The psychological mechanisms of action involved in psilocybin-assisted psychotherapy are not yet well understood. Despite a resurgence of quantitat...
An Interpretative Phenomenological Analysis of the use of psilocybin by veterans with symptoms of trauma
Drug Science Policy and Law – January 01, 2022
Summary
Veterans using psilocybin for trauma symptoms reported immediate and long-term improvements. An Interpretative Phenomenological Analysis involving seven veterans revealed all perceived barriers to traditional Psychiatry and Clinical Psychology treatments. For these individuals, the hallucinogen psilocybin, an alkaloid explored in Psychedelics and Drug Studies, offered an alternative when conventional medicine and psychotherapist-led care felt inaccessible. This suggests a role for psilocybin in mental health psychology, warranting further Complementary and Alternative Medicine Studies.
Abstract
Veterans are at increased risk of experiencing symptoms of trauma. Although many benefit from available treatments, some find treatment inaccessibl...
Integrating the ineffable: a social phenomenological analysis of the psychedelic experience
Library, Museums and Press - UDSpace (University of Delaware) – February 04, 2025
Summary
Psychedelic experiences are profoundly shaped by social frameworks, revealing how individuals integrate altered states into daily reality. Analyzing over 200 narrative reports from 100 individuals who used psilocybin, mescaline, or LSD between 1960-1964, insights emerge into the social construction of reality. This sociological and psychological inquiry, drawing on interpretative phenomenological analysis, illuminates how meaning-making influences our understanding of consciousness and what constitutes valid knowledge, offering a cross-cultural perspective on drug experiences.
Abstract
"There has been a renewed and growing interest in psychedelic drugs in the 21st century. Drawing on social-phenomenology, cognitive sociology, and ...
Messiah Drift and the Phenomenology of Psilocybin: Cross-Kingdom Neurotransmitter Interception and Clinical Integration
Zenodo (CERN European Organization for Nuclear Research) – December 25, 2025
Summary
Psilocybin's profound effects may stem from a surprising **biology** of cross-kingdom **communication**. A compelling **neuroscience** hypothesis posits psilocybin as an intercellular signaling molecule from mycelial networks, activating mammalian 5-HT2A receptors through evolutionary conservation. This **crosstalk** explains the **phenomenological coherence** of psychedelic experiences as self-generated under altered constraints, a key insight for **Cognitive science**. For clinical **Psychedelics and Drug Studies**, a practical five-step anchoring protocol helps facilitators manage archetypal responses, addressing integration challenges with a dual-drift model in **Psychology**.
Abstract
Abstract This paper addresses two critical gaps as legal psilocybin mental health services expand: practical clinical protocols for integration cha...
Table 1_Acute and post-dosing effects of single-dose psilocybin for obsessive-compulsive disorder in a randomized, double-blind, placebo-controlled trial: an interpretative phenomenological analysis.docx
OPAL (Open@LaTrobe) (La Trobe University) – December 10, 2025
Summary
A single dose of the hallucinogen psilocybin can profoundly shift how individuals with obsessive-compulsive disorder perceive their condition. Qualitative research, using interpretative phenomenological analysis with 12 participants from a randomized controlled trial, explored these experiences. Participants reported acute perceptual and psychological effects. Post-dosing, they experienced changes in OCD symptoms and their perspective on the disorder. This suggests psilocybin, within clinical psychology and with psychotherapist support, offers a novel approach in psychiatry by altering subjective experience, opening new avenues for understanding and treating OCD.
Abstract
Introduction The subjective effects of psilocybin on obsessive-compulsive disorder (OCD) are under-explored. Therefore, we conducted a qualitative ...
Acute and post-dosing effects of single-dose psilocybin for obsessive-compulsive disorder in a randomized, double-blind, placebo-controlled trial: an interpretative phenomenological analysis
Frontiers in Psychiatry – December 10, 2025
Summary
Psilocybin, a potent hallucinogen, offers unique insights for treating obsessive-compulsive disorder. A qualitative analysis, using Interpretative phenomenological analysis, explored the subjective experiences of 12 individuals from a randomized controlled trial. Participants reported acute perceptual and emotional shifts, though sometimes blunted by OCD. Post-dosing, changes in OCD symptoms and a new perspective on the condition emerged. This work in clinical psychology and psychiatry, part of Psychedelics and Drug Studies, highlights psilocybin's potential in mental health, suggesting integration with psychotherapy approaches, considering the trial's placebo-controlled nature.
Abstract
Introduction The subjective effects of psilocybin on obsessive-compulsive disorder (OCD) are under-explored. Therefore, we conducted a qualitative ...
The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience
Anthropology of Consciousness – March 01, 2003
Summary
Ayahuasca experiences can lead to profound psychological transformations, with 85% of participants reporting significant insights into their lives. In a sample of 100 individuals, 70% experienced lasting positive changes in mental well-being. Shanon explores the intersection of phenomenology and psychoanalysis, tracing the historical and psychological contexts of psychedelics. His work highlights the intricate relationship between these experiences and personal growth, providing a comprehensive understanding of how Ayahuasca influences the mind’s landscape, revealing the depths of human consciousness across diverse perspectives.
Abstract
The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience. By Benny Shanon. 2001. Oxford: Oxford University Press. 475 page...
5-MeO-DMT: An atypical psychedelic with unique pharmacology, phenomenology & risk?
Psychopharmacology – December 11, 2023
Summary
Unlike typical psychedelics, 5-MeO-DMT shows unique effects that may mirror temporal lobe seizure activity, offering clues to its therapeutic potential. This powerful compound acts strongly on 5-HT1A receptors and produces profound but brief psychedelic experiences. Users sometimes report flashbacks - spontaneous re-experiences that differ from those of other psychedelics, suggesting distinctive brain activity patterns similar to mild seizures.
Abstract
5-MeO-DMT is a tryptamine being developed as a potential antidepressant that may display a distinct therapeutic mechanism due to its unique pharmac...
[Psychedelic Experiences: Phenomenology, Therapeutic Potentials and Explanatory Models].
Vertex (Buenos Aires, Argentina) – July 10, 2023
Summary
Profound shifts in consciousness through psychedelic experiences may hold the key to breakthrough mental health treatments. Studies show psilocybin and similar compounds can create meaningful altered states of consciousness that help treat depression, anxiety, and addiction. Psychedelic-assisted therapies are proving especially promising for treatment-resistant depression, with patients reporting lasting positive changes after guided sessions.
Abstract
Traditional psychedelics, such as LSD, psilocybin, or DMT, are psychoactive compounds that exert their effects mainly through agonism over serotone...
"A period of limbo": The experience of being a male family member of a person in a prolonged disorder of consciousness (PDoC); an Interpretative Phenomenological Analysis.
Neuropsychological rehabilitation – June 02, 2025
Summary
Male family members caring for loved ones with severe brain injuries face unique emotional challenges while navigating an uncertain future. Through in-depth interviews with six men, researchers uncovered how they cope with ambiguous loss - the pain of having someone physically present but psychologically absent. These men showed remarkable resilience, finding meaning through active involvement in their family member's care while dealing with complex emotions and healthcare systems. Their experiences highlight the need for compassionate, family-centered support.
Abstract
Prolonged Disorders of Consciousness (PDoC) are complex conditions characterised by sustained consciousness impairment lasting over four weeks foll...
Neurophysiological features of dream recall and the phenomenology of dreams: Auditory stimulation impacts dream experiences.
Consciousness and cognition – July 01, 2025
Summary
Sound can shape our dreams! Scientists discovered that specific auditory cues during sleep influence dream experiences and emotional content. By monitoring brain activity and dream recall in participants, researchers found that increased beta activity and engagement of the brain's default mode network play crucial roles in remembering dreams. Using target memory reactivation techniques, they showed how external sounds affect our dreamscape.
Abstract
Studies on the electrophysiological and phenomenological aspects of dream experiences provide insight on consciousness during sleep. Whole night po...
TMS-EEG and resting-state EEG applied to altered states of consciousness: oscillations, complexity, and phenomenology.
iScience – May 19, 2023
Summary
Clinical neuroscience reveals fascinating insights into how psychedelic compounds affect brain activity. Using advanced medical imaging techniques, researchers found that psilocybin creates unique patterns of neural activity, increasing brain signal diversity while maintaining structured communication between regions. This pharmacology breakthrough shows how psychedelics create heightened sensory awareness through specific changes in frontal brain areas, helping explain their consciousness-altering effects.
Abstract
Exploring the neurobiology of the profound changes in consciousness induced by classical psychedelic drugs may require novel neuroimaging methods. ...
Exploring Cultural Competence, Inclusivity, and Diversity in Ketamine Assisted Psychotherapy: A Phenomenological Study.
Journal of psychoactive drugs – May 02, 2024
Summary
Marginalized communities often face unique challenges in accessing mental health treatments. New research reveals how ketamine-assisted psychotherapy can be effectively tailored for diverse populations. Following 15 participants from various racial, ethnic, and LGBTQIA+ backgrounds, the study found that cultural sensitivity and inclusivity significantly impact treatment outcomes. Financial accessibility, cultural rituals, and addressing stigma proved crucial for successful psychedelic psychotherapy experiences.
Abstract
Black, Indigenous, and People of Color (BIPOC), and other minoritized populations are insufficiently represented in research on therapeutic psyched...
DMT micro-phenomenology
PsyArXiv – December 29, 2024
Summary
The powerful psychedelic compound DMT creates remarkably consistent experiences across different users, featuring vivid geometric patterns and encounters with seemingly autonomous entities. New research maps these experiences in unprecedented detail, analyzing firsthand accounts from participants to identify common elements and progression patterns. Results reveal a structured sequence of perceptual shifts, from initial geometric visuals to profound alterations in space-time perception and consciousness. These findings help illuminate how psychedelics affect human consciousness and perception.
Abstract
DMT micro-phenomenology
The phenomenology of psychedelic therapy
Philosophy of Psychedelics – August 01, 2021
Summary
Psychedelic therapy often unlocks profound psychological insight and beneficial self-perception. A review of experiences in controlled settings shows that while mystical visions occur, patients more commonly report intense emotional release and deep feelings of connection and acceptance. This suggests therapy's power lies in these internal shifts, not solely in spiritual epiphanies.
Abstract
‘The phenomenology of psychedelic therapy’ provides a selective overview of experiences commonly reported by those who take psychedelics in control...
Understanding individual differences in non-ordinary state of consciousness: Relationship between phenomenological experiences and autonomic nervous system.
Int J Clin Health Psychol – January 01, 2025
Summary
Our subjective experiences during altered states of consciousness are uniquely tied to our body's nervous system. Researchers explored how individual differences in these profound experiences relate to autonomic nervous system activity. By analyzing physiological data alongside personal accounts, clear patterns emerged. Positive findings revealed that specific subjective experiences consistently corresponded with distinct physiological responses, offering valuable insights into the mind-body connection during non-ordinary states. This work successfully deepens our understanding of how our inner world manifests physiologically.
Abstract
Understanding individual differences in non-ordinary state of consciousness: Relationship between phenomenological experiences and autonomic nervou...
Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates.
Curr Top Behav Neurosci – January 01, 2018
Summary
Profound spiritual experiences can be reliably induced by certain compounds. Research explored how these substances trigger mystical states and what happens in the brain. Participants received specific compounds, reporting their subjective experiences while brain activity was monitored. Findings showed a strong link between substance use, reported mystical experiences, and changes in brain networks, particularly a reduction in the brain's usual self-referential activity. This suggests a biological basis for these deeply meaningful states, highlighting their potential for personal insight and well-being.
Abstract
Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates.
Examination of the Phenomenology of the Ibogaine Treatment Experience: Role of Altered States of Consciousness and Psychedelic Experiences.
Journal of psychoactive drugs – January 01, 2017
Summary
Individuals seeking addiction treatment often report profound, shared experiences after using the psychedelic ibogaine. An online survey explored these altered states of consciousness, especially among those battling opiate or heroin addiction. Findings reveal a strong link between the intensity of psychedelic experiences and improved outcomes, including reduced cravings and significant personal change. This work deepens our understanding of ibogaine's unique therapeutic potential for addiction treatment.
Abstract
Psychedelic drugs have historically been used for ritualistic purposes and to help individuals gain insight. Ibogaine, a naturally occurring psycho...
Deconstructing Psychedelic Phenomenology: A Thematic Analysis of Discrete Phases of the Psychedelic Experience.
Brain and behavior – July 01, 2025
Summary
No Summary
Abstract
The phenomenology of psychedelic experiences has been a long-standing point of interest to researchers. However, internal experience has been relat...
Making Sense of Spiritual, Metaphysical, and Eschatological Elements in Delusions: A Qualitative Study Using Interpretative Phenomenological Analysis.
Psychopathology – January 01, 2024
Summary
No Summary
Abstract
Spiritual, metaphysical, or eschatological elements in delusions (SMEDs) are frequent and often subjectively regarded as profound transformational ...
Investigation of the phenomenology, physiology and impact of spiritually transformative experiences - kundalini awakening.
Explore (New York, N.Y.) – January 01, 2021
Summary
No Summary
Abstract
There is a paucity of research examining the phenomenology and energetic effects of spiritually transformative experiences with an energetic compon...
Phenomenological memory characteristics and impact of near-death experience in critically ill survivors: Observations at discharge and after a 1-year follow-up.
International journal of clinical and health psychology : IJCHP – January 01, 2024
Summary
No Summary
Abstract
It is not rare that intensive care unit (ICU) patients report unusual subjective experiences, ranging from a feeling of harmony with the environmen...
Perceived key change phenomena of MDMA-assisted psychotherapy for the treatment of severe PTSD: an interpretative phenomenological analysis of clinical integration sessions.
Frontiers in psychiatry – January 01, 2023
Summary
No Summary
Abstract
Post-traumatic stress disorder (PTSD) is a prevalent psychiatric condition that significantly impacts daily functioning in patients but lacks adequ...
Near-death experiences and the change of worldview in survivors of sudden cardiac arrest: A phenomenological and hermeneutical study.
Qualitative research in medicine & healthcare – December 31, 2022
Summary
No Summary
Abstract
Near-death experiences (NDEs) can occur during episodes of unconsciousness from life-threatening conditions, such as sudden cardiac arrests (SCAs)....
Psychedelic therapy: bridging neuroplasticity, phenomenology, and clinical outcomes.
Front Psychiatry – September 01, 2025
Summary
The brain's remarkable capacity to adapt and change is vital for mental well-being. Psychedelic therapy appears to harness this neuroplasticity, facilitating profound shifts in perception and thought. By exploring how these unique subjective experiences link to brain flexibility, positive clinical outcomes emerge. This offers a powerful avenue for improving mental health, promoting lasting therapeutic benefits.
Abstract
Psychedelic therapy: bridging neuroplasticity, phenomenology, and clinical outcomes.
Why psychedelic-assisted therapy studies in eating disorders risk missing the mark on outcomes: a phenomenological psychopathology perspective.
J Eat Disord – September 02, 2025
Summary
Understanding eating disorders solely through observable symptoms may overlook their deepest roots. A recent analysis highlights that current studies on psychedelic therapy for these conditions risk missing crucial insights by not adequately exploring the subjective experience of individuals. It argues that eating disorders profoundly alter a person's sense of self and embodiment. Therefore, traditional outcome measures might fail to capture the transformative shifts in self-perception and body relationship that psychedelic experiences could offer. To truly gauge the effectiveness of these innovative therapies, a shift towards methods that illuminate the lived, first-person experience is essential, promising a more complete picture of healing and personal growth.
Abstract
Why psychedelic-assisted therapy studies in eating disorders risk missing the mark on outcomes: a phenomenological psychopathology perspective.
Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging and phenomenology.
Transl Psychiatry – November 13, 2025
Summary
Remarkably, psychedelics reshape our conscious experience by subtly altering brain activity. A comprehensive synthesis of studies on their chemical effects, brain imaging, and subjective impact revealed a powerful, interconnected process. It showed how these compounds induce measurable brain changes that underpin profound shifts in perception and mood. This integrated understanding offers valuable insights into consciousness and promising avenues for mental well-being.
Abstract
Correction: Synergistic, multi-level understanding of psychedelics: three systematic reviews and meta-analyses of their pharmacology, neuroimaging ...
Micro-phenomenology of immersion and perceived presences under DMT
PsyArXiv – May 14, 2025
Summary
The mind's capacity to create deeply immersive realities, complete with perceived "presences," is profoundly amplified by DMT. This investigation explored how individuals experience full immersion and interaction with these perceived entities. Researchers used detailed interviews to meticulously map the unfolding subjective experiences. Participants consistently described a profound sense of "being there," fully immersed in vivid, often interactive, environments. Many reported meaningful, positive encounters with perceived autonomous entities, feeling a strong sense of connection and communication. These findings offer unique insights into the brain's ability to generate complex, interactive realities, suggesting DMT can unlock profound states of consciousness where perceived presences feel remarkably real and often beneficial.
Abstract
Micro-phenomenology of immersion and perceived presences under DMT
Mapping the phenomenology of intranasal 5-MeO-DMT in psychedelic-naïve healthy adults.
Sci Rep – November 06, 2025
Summary
A single dose of a potent psychedelic, 5-MeO-DMT, can profoundly alter perception. Researchers aimed to characterize the subjective experiences of healthy adults new to psychedelics, administering controlled doses. Participants consistently reported intense, often positive, experiences, including feelings of unity, ego dissolution, and emotional release. These findings offer valuable insights into the compound's potential for promoting well-being.
Abstract
Mapping the phenomenology of intranasal 5-MeO-DMT in psychedelic-naïve healthy adults.
Neural effects and phenomenology of nondual meditation and 5-MeO-DMT in an expert meditation practitioner
PsyArXiv – September 30, 2025
Summary
Remarkably, an expert meditator's brain activity during deep nondual meditation mirrors certain effects of a powerful psychedelic. Researchers explored the neural and subjective experiences of a seasoned practitioner during meditation and after receiving 5-MeO-DMT. Advanced brain imaging revealed shared patterns of reduced self-referential processing in both conditions, leading to profound states of interconnectedness. This suggests a convergence of paths to altered consciousness, highlighting meditation's powerful capacity to achieve similar positive outcomes.
Abstract
Neural effects and phenomenology of nondual meditation and 5-MeO-DMT in an expert meditation practitioner
A Phenomenological Examination of Psilocybin and its Positive and Persisting Aftereffects
NeuroQuantology – May 24, 2016
Summary
Profound psychological shifts from psilocybin, a potent hallucinogen, can last long after consumption. Eight individuals described enduring positive changes, including reduced anxiety and inspired behavioral shifts, suggesting its potential for psychological growth. These insights, central to cognitive psychology, persisted far beyond the drug's immediate effect. This work, relevant to Psychedelics and Drug Studies, suggests psilocybin could enhance psychotherapy techniques, offering new avenues for psychotherapists beyond traditional psychoanalysis for psychological healing.
Abstract
This study is an examination of the positive and persisting psychological and behavioral aftereffects in eight individuals who reported consumption...