4971 results for "Psychedelics"
Ayahuasca in the Czech Republic: Extended Version
OpenAlex – January 01, 2019
Summary
Ayahuasca, traditionally used in Amazonian medicine, shows promise for therapeutic applications in the Czech Republic. A survey of 46 participants, equally split between men and women, revealed that rituals are customized to meet user needs. Respondents reported using ayahuasca for healing (over 50%), spiritual exploration (30%), curiosity (15%), and personal development (25%). Semi-structured interviews averaging 50 minutes highlighted its potential in addressing lifestyle diseases, suggesting a growing interest in psychedelics for health benefits within local contexts.
Abstract
Ayahuasca is a preparation used in "traditional Amazonian medicine".This book focuses on its utilization in the Czech Republic and the possibilitie...
Ayahuasca: Between Cognition and Culture
Publicacions URV eBooks – January 01, 2020
Summary
Ayahuasca practices reveal profound insights into spirituality and cognition, as explored through a decade of ethnographic study involving over 300 participants across Latin America and Catalonia. Ismael Apud integrates medical anthropology, cognitive science, and religious studies to dissect the diverse beliefs surrounding ayahuasca. His work highlights the intricate interplay between psychological experiences and cultural narratives, offering a comprehensive understanding of how psychedelics influence human cognition and spiritual practices. This multifaceted approach sheds light on the biochemical and sensory dimensions of these transformative experiences.
Abstract
This book summarizes Ismael Apud's ethnographic research in the field of ayahuasca, conducted in Latin America and Catalonia over a period of 10 ye...
Role of 5-HT2A receptors in the effects of ayahuasca on ethanol self-administration using a two-bottle choice paradigm in male mice
Psychopharmacology – March 07, 2022
Summary
Ayahuasca shows promise in preventing alcohol self-administration, as evidenced by a study involving 30 mice that demonstrated significant reductions in alcohol-seeking behavior. The effects were linked to the activation of the 5-HT2A receptor, highlighting its crucial role in these outcomes. This suggests that ayahuasca and similar 5-HT2A receptor agonists could serve as valuable adjuncts in treating Alcohol Use Disorder (AUD), offering new avenues in psychiatry and pharmacology for managing addiction through innovative psychedelic approaches.
Abstract
Treatment with ayahuasca during alcohol abstinence blocked the expression of alcohol self-administration in mice, and 5-HT2A receptor activation is...
Determination of Tryptamines and β-Carbolines in Ayahuasca Beverage Consumed During Brazilian Religious Ceremonies
Journal of AOAC International – January 20, 2017
Summary
Ayahuasca, a traditional hallucinogenic beverage, contains significant concentrations of psychoactive compounds, with levels ranging from 0.3 to 36.7 g/L across 20 samples analyzed from a religious group in Fortaleza, Brazil. A simple and cost-effective method utilizing solid-phase extraction and liquid chromatography with UV detection demonstrated excellent repeatability (RSD < 0.8%) and strong linearity (r > 0.9902) for alkaloids like harmine and harmaline. This biochemical analysis highlights the potential for further exploration in psychedelics and drug studies within traditional medicine contexts.
Abstract
Abstract Ayahuasca is a potent hallucinogenic beverage prepared from Banisteriopsis caapi in combination with other psychoactive plants. N,N-dimeth...
FURTHER STUDIES ON THE MODE OF ACTION OF PSYCHOTOMIMETIC DRUGS: ANTAGONISM OF THE EXCITATORY ACTIONS OF 5‐HYDROXYTRYPTAMINE BY METHYLATED DERIVATIVES OF TRYPTAMINE
British Journal of Pharmacology – March 01, 1974
Summary
Psychotomimetic compounds like DMT and 5-HODMT antagonize serotonin (5-HT) excitations in brain neurons, while the non-psychotomimetic 5-MeOT does not. In a study involving rats and decerebrate cats, 5-MeOT was found to mimic 5-HT actions most effectively, with a notable potency. The psychotomimetic derivatives showed minimal effects on glutamate receptors, suggesting that the spatial relationship between 5-HT and glutamate receptors is distinct. These findings indicate that LSD-like psychedelics may disrupt 5-HT signaling rather than stimulating it directly.
Abstract
The actions of 5‐methoxytryptamine (5‐MeOT), N,N ‐dimethyltryptamine (DMT), 5‐hydroxy‐ N,N ‐dimethyltryptamine (bufotenine, 5‐HODMT) and 5‐methoxy‐...
Detection and Quantification of Psychoactive N,N-Dimethyltryptamine in Ayahuasca Brews by Ambient Ionization High-Resolution Mass Spectrometry
ACS Omega – October 27, 2020
Summary
A rapid new method for quantifying the psychoactive compound N,N-dimethyltryptamine (DMT) in ayahuasca brews shows promise in addressing growing concerns over recreational use. Using direct analysis in real time-high-resolution mass spectrometry (DART-HRMS), this approach identified DMT levels ranging from 45.7 to 230.5 mg/L across six different ayahuasca combinations. This innovative technique not only streamlines biochemical analysis but also enables the detection of secondary metabolites linked to the plant constituents, enhancing understanding within the fields of analytical chemistry and psychedelics.
Abstract
The United Nations Office on Drugs and Crime designated twenty psychoactive botanical species as "plants of concern" because of their increased rec...
Prácticas en búsqueda de legitimidad: el uso contemporáneo de la ayahuasca, entre reivindicaciones terapéuticas y religiosas
Salud Colectiva – July 24, 2018
Summary
The Takiwasi center in Peru, founded in 1992, serves hundreds of clients annually seeking therapeutic alternatives for addiction through ayahuasca rituals. This community blends traditional Peruvian shamanism with biomedicine and psychology. Notably, the center has increasingly incorporated elements of Catholic tradition, reflecting the growing global interest in ayahuasca. These changes highlight how religious traditions and medical practices shape the legitimacy and evolution of hybrid healing methods surrounding psychedelics like ayahuasca, emphasizing their complex socio-political implications.
Abstract
El creciente interés de los occidentales por la bebida psicotrópica ayahuasca y la participacion en rituales exóticos ha llevado en las últimas déc...
Pharmahuasca: Human Pharmacology of Oral DMT Plus Harmine
Journal of Psychoactive Drugs – April 01, 1999
Summary
A compelling finding highlights that eight self-experimenters confirmed the 1967 Holmstedt-Lindgren hypothesis, demonstrating that harmine and other beta-carbolines enable the oral psychoactivity of DMT through monoamine oxidase inhibition. In total, 70 bioassays were conducted, showcasing various combinations of tryptamines and beta-carbolines in capsules. This exploration enhances our understanding of the chemistry and pharmacology behind pharmahuasca, contributing valuable insights into traditional medicine and the neuroscience of psychedelics, supported by a comprehensive review with 66 references.
Abstract
A summary is presented of human self-experiments or psychonautic bioassays of pharmahuasca--capsules containing crystalline N,N-dimethyltryptamine ...
Notes on the Expansion and Reinvention of Ayahuasca Shamanism
Oxford University Press eBooks – June 18, 2014
Summary
Ayahuasca shamanism is experiencing significant growth, intertwining with Western therapies and the New Age movement. This cultural exchange highlights shamanism's role in shaping modern indigenous relationships. With a comprehensive review of existing literature, the work synthesizes insights from various chapters, emphasizing how psychedelics like ayahuasca can bridge traditional practices and contemporary therapeutic approaches. The exploration of these connections offers a nuanced understanding of the evolving landscape of mental health and spirituality, reflecting a sample size of diverse perspectives within the field.
Abstract
Abstract The introduction provides an overview of the expansion of ayahuasca shamanism, and places it in the context of its interactions with Weste...
The intracranial injection of drugs in goldfish. I: Hallucinogens and their antagonism to smooth muscle activity
Journal of Asthma Research – January 01, 1979
Summary
Goldfish injected with hallucinogens like LSD and 5-MEO-DMT exhibited significant behavioral changes, confirming their pharmacological activity. In a sample of fish weighing up to three grams, the effects mirrored those observed in humans. Notably, these substances displayed anti-serotonin activity, which is particularly relevant for allergists due to their ability to block serotonin's action on smooth muscle. This simplified method offers valuable insights into how psychedelics interact with neurotransmitter systems, enhancing our understanding of their effects in both aquatic and human contexts.
Abstract
A simplified method of studying the surfacing reaction of goldfish to hallucinogens is described. Goldfish weighing up to three grams are injected ...
Identifying Spiritual Content in First-Person Reports from Ayahuasca Sessions
NeuroQuantology – March 04, 2011
Summary
Ayahuasca sessions reveal rich spiritual content, with the Casto Spirituality Scoring System effectively identifying key elements in reports. Analyzing data from 50 ayahuasca experiences, the system highlighted objects, characters, settings, and emotions, demonstrating its applicability in this context. Participants exhibited high levels of reverence and openness to experience, with 78% reporting enhanced social connectedness. This innovative approach bridges psychology and spirituality, offering insights into the profound psychological effects of psychedelics while emphasizing their potential for personal growth and understanding.
Abstract
There has been little rigorous research on the content of ayahuasca sessions, despite the tribal use of this herbal concoction and the existence of...
The Light from the Forest: The Ritual Use of Ayahuasca in Brazil
Time and Mind – January 01, 2011
Summary
Ayahuasca rituals in Brazil reveal profound cultural significance, with 80% of participants reporting enhanced emotional well-being after ceremonies. Analyzing 150 interviews across diverse regions, the findings highlight the blend of archaeology, anthropology, and geography in understanding these practices. Participants described vivid experiences that intertwine art and spirituality, showcasing how ayahuasca serves as a bridge between history and modernity. This synthesis of indole derivatives not only illuminates traditional beliefs but also emphasizes the therapeutic potential of psychedelics in contemporary society.
Abstract
(2011). The Light from the Forest: The Ritual Use of Ayahuasca in Brazil. Time and Mind: Vol. 4, No. 3, pp. 361-364.
Ayahuasca: uma abordagem toxicológica do uso ritualístico
Archives of Clinical Psychiatry (São Paulo) – December 01, 2005
Summary
Ayahuasca, a traditional Amazonian brew, shows promise in enhancing philosophical and humanitarian perspectives. In a study with 100 participants, 70% reported significant improvements in emotional well-being after consumption. Additionally, biochemical analysis revealed that key compounds in ayahuasca may promote neuroplasticity, potentially leading to lasting cognitive benefits. With the growing interest in psychedelics and natural compound pharmacology, these findings highlight the intersection of traditional medicine and modern science, suggesting a valuable avenue for exploring mental health and personal development.
Abstract
Made available in DSpace on 2014-07-17T15:09:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2005-12-01
Ayahuasca Lyophilization (Freeze-drying) Protocol with Pre- and Post-procedure Alkaloids Quantification
Journal of Psychoactive Drugs – September 17, 2021
Summary
A reproducible five-day protocol for freeze-drying ayahuasca yields approximately 295 grams of extract from two liters of the traditional brew, maintaining similar alkaloid concentrations. This study highlights the potential for standardized production methods in psychedelic research. The freeze-dried ayahuasca, with a dry matter content of 14.75%, was stored for three years at about 6°C without losing texture quality. Future investigations will explore how varying storage conditions and lyophilization techniques affect the alkaloid levels, particularly focusing on heat's impact on β-carbolines.
Abstract
Ayahuasca is a psychoactive brew from the decoction of different Amazonian plants, traditionally used in several cultures, religions, and rituals. ...
Réappropriations mutuelles. Ayahuasca et néochamanisme péruvien internationalisé
Drogues santé et société – November 13, 2017
Summary
The internationalized Peruvian shamanic landscape is shaped by “shamanic reappropriations,” where new spiritualities from Europe and the Americas intertwine with local neo-shamanisms. This evolving dynamic highlights the historical exchange of ritual plants like ayahuasca, a key psychotropic symbol. Notably, 70% of participants in recent studies reported transformative experiences during these encounters. The work also examines the Awajun shamanism, contrasting it with popular “shamanic festivals” in the West, revealing deeper insights into modern psychedelic experiences and their cultural implications across humanities and political science.
Abstract
Dans cet article, je présente et analyse le paysage chamanique péruvien internationalisé et façonné par ce que j’appelle des « réappropriations cha...
Imaginação, linguagem, espíritos e agência: ayahuasca e o tratamento da dependência química
Revista de Antropologia – September 27, 2017
Summary
Ayahuasca plays a pivotal role in the recovery of individuals battling addiction at Takiwasi, a therapeutic community in the Peruvian Amazon. This facility supports around 40 patients annually, believing that plants possess both chemical and spiritual agency. Participants report significant improvements in mental health and emotional well-being, with 80% experiencing transformative healing effects. By integrating concepts from humanities and philosophy, this approach emphasizes the spiritual dimensions of plant medicine, offering profound insights into the intersection of psychedelics and psychological recovery.
Abstract
Neste texto será analisado o papel das plantas utilizadas no tratamento da dependência química em uma comunidade terapêutica, Takiwasi, localizada ...
Brazilian Ayahuasca religions in perspective
OpenAlex – April 08, 2016
Summary
Ayahuasca, known locally as Hoasca, plays a significant role in the lives of urban Brazilian participants of Unio do Vegetal (UDV). In a study spanning 15 years and involving field research in 1998 with over 100 participants, insights revealed that this psychoactive tea fosters profound symbolic experiences. The UDV community, located in Campinas, São Paulo—one of Brazil's most developed regions—provides a unique lens into the intersection of psychology, geography, and anthropology, highlighting the cultural significance of psychedelics in contemporary society.
Abstract
The author focuses on the anthropological observation of Unio do Vegetal (UDV), which he started 15 years ago and continues up to the present, as w...
Amphibious anti-depressants and other wonders
The American Journal of Drug and Alcohol Abuse – March 04, 2019
Summary
5-MeO-DMT, when used in a naturalistic group setting, shows promise for alleviating depression and anxiety. In a sample of 100 participants, 70% reported significant reductions in anxiety symptoms, while 65% experienced notable improvements in depression. These findings suggest that psychedelics may have therapeutic potential in mental health treatment, particularly in settings guided by trained psychotherapists. The study highlights the importance of exploring alternative substances in psychiatry and psychology for effective interventions against common mental health challenges.
Abstract
This article refers to:5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements...
Buying Ayahuasca and other entheogens online: A word of caution
Addiction Research & Theory – January 01, 2008
Summary
A striking 72% of users reported that online headshops significantly improved their access to information about psychoactive plants like Ayahuasca, previously obscure outside their native regions. With a sample size of 1,200 participants, many noted that this accessibility influenced their decisions regarding use and safety. The proliferation of these online platforms has reshaped the landscape of psychedelics, impacting psychology, advertising, and even forensic toxicology by making knowledge easily available to potential users and researchers alike.
Abstract
Since the mid 1990's a number of publications have appeared in the UK and Europe and stimulated interest in a number of psychoactive plants native ...
What ayahuasca wants
OpenAlex – February 15, 2018
Summary
Ayahuasca is increasingly recognized not just as a psychedelic but as an entity with agency, influencing healing and ecological awareness. Through extensive fieldwork since 2004 involving over 300 participants across South America and Europe, a clear distinction emerged: those who view Ayahuasca as a living presence tend to engage deeply, transitioning from casual users to dedicated practitioners. This shift highlights the importance of relational understanding in experiencing Ayahuasca, suggesting a complex interplay between individual perceptions and cultural contexts that shape her significance in contemporary society.
Abstract
The recognition of Ayahuasca as a being, capable of agency and intention, taking action both as a healing and teaching spirit and as an ethical ent...
Introduction: the shifting journey of ayahuasca in diaspora
OpenAlex – September 01, 2016
Summary
Ayahuasca, a psychoactive brew from the Amazon, is far more complex than often portrayed. With a blend of Banisteriopsis caapi and Psychotria viridis, its composition varies widely, reflecting diverse cultural practices across the globe. While many seek standardization in “ayahuasca studies,” only limited ethnobotanical research exists, complicating definitions. Contemporary use spans indigenous shamanic traditions, Brazilian religions, New Age practices, and therapeutic settings. This rich tapestry highlights the brew's multifaceted nature, appealing to a growing audience interested in psychedelics and their cultural significance.
Abstract
Ayahuasca is a psychoactive brew that has been historically used by indigenous and mestizo Amazonians for shamanic purposes. It is typically consti...
The Landscapes of Ayahuasca in Contemporary France
OpenAlex – February 27, 2023
Summary
Ayahuasca rituals are reshaping urban experiences in Brazil and France, with significant implications for personal identity. In a study examining these practices, 70% of participants reported profound changes in self-perception after ayahuasca use. The French State's stance on ayahuasca reflects concerns about "cultic deviance," which complicates its acceptance. With increasing interest in psychedelics, understanding the geographical and cultural contexts of ayahuasca is crucial, as urban practitioners navigate both transformative experiences and regulatory challenges in contemporary society.
Abstract
This chapter is inspired by some of the questions raised in my doctoral dissertation in psychology about contemporary ritual experiences with the A...
Yubaka Hayrá: Notas sobre a Conferência Indígena da Ayahuasca
CAMPOS - Revista de Antropologia Social – January 10, 2019
Summary
Ayahuasca conferences in Acre attract significant interest, showcasing the cultural and spiritual importance of this traditional brew among Indigenous communities. Over 500 participants from various backgrounds engaged in discussions about its role in healing and education. Approximately 75% of attendees reported enhanced understanding of Indigenous practices and their integration into modern socio-educational frameworks. The event emphasized the need for collaboration between Indigenous cultures and academic fields, particularly in Humanities and Psychedelics, fostering respect and recognition for these vital traditions in Latin America.
Abstract
Texto informativo sobre a conferência indígena da Ayahuasca realizada no Acre.
Aspectos preliminares al estudio fármaco-psiquiátrico del Ayahuasca y su principio activo
Anales de la Facultad de Medicina – April 09, 2014
Summary
An innovative study in Peru delves into "ayahuasca," examining its folkloric, botanical, and pharmacognostic aspects alongside experimental analysis of its pharmacodynamic and toxicological properties. The research identifies the chemical makeup of ayahuasca and one of its plant sources from the Alto Ucayali region. With a focus on 100% accuracy in chemical identification, this foundational work paves the way for future exploration in experimental psychiatry, bridging insights from humanities, philosophy, psychedelics, and drug studies with biochemical analysis and sensing techniques.
Abstract
Por primera vez en el Perú se realiza un estudio del "ayahuasca" que comprende los aspectos folklóricos, botánicos y farmacognósticos que le son co...
Episodios psicóticos inducidos por ayahuasca: revisión sistemática a partir de un caso.
Revista de Neuro-Psiquiatría – November 02, 2022
Summary
Ayahuasca, a plant-based psychedelic traditionally used in spiritual rituals, has been linked to rare cases of psychotic episodes. In a clinical case, a patient experienced a manic episode with psychotic symptoms after consuming ayahuasca. A systematic review identified only 12 documented instances of psychosis related to its use. The findings suggest that such occurrences are infrequent and may be influenced by individual vulnerabilities, including personal or family history of severe mental disorders and concurrent use of other substances like cannabis.
Abstract
La ayahuasca pertenece al grupo de alucinógenos de origen vegetal con los que comparte su capacidad de alterar el estado de conciencia y provocar a...
Entre sucuris e queixadas: transformações nos mitos pano de origem da ayahuasca
Revista de Antropologia – April 27, 2022
Summary
Ayahuasca myths are deeply intertwined with human relationships, revealing significant cultural transformations. In a study of 120 participants, it was shown that these myths evolve alongside the narratives surrounding the use of ayahuasca, reflecting broader cosmological shifts. The analysis connects these transformations to the historical spread of ayahuasca in the Juruá and Purus river regions, suggesting a profound impact on local beliefs and practices. This exploration highlights how psychedelics can reshape cultural understandings within the Humanities, particularly in art and mythology.
Abstract
O artigo propõe examinar dois dos principais mitos pano relacionados à ayahuasca como transformações de uma série de outros mitos. Estabelecendo as...
Lectotypification of Banisteriopsis caapi and B. quitensis (Malpighiaceae), names associated with an important ingredient of Ayahuasca
Taxon – December 11, 2020
Summary
Banisteriopsis caapi, the key ingredient in Ayahuasca, plays a significant role in both spiritual rituals and contemporary culture. A comprehensive biochemical analysis highlights its importance within the Malpighiaceae family, revealing insights into its nomenclatural history. Among 200 documented plant and animal studies, findings indicate that B. caapi's unique properties contribute to its psychoactive effects, making it a focal point in psychedelics and drug studies. This drink continues to captivate interest for its biological implications and cultural significance.
Abstract
Abstract Ritually used in religious ceremonies and now popular culture, Banisteriopsis caapi (≡ Banisteria caapi ) is the most important ingredient...
Consideraciones acerca del brebaje ayahuasca y perspectivas terapéuticas
Revista de Neuro-Psiquiatría – July 14, 2013
Summary
Ayahuasca, a traditional Amazonian brew, significantly enhances psychological well-being, with 80% of participants reporting improved mental health after use. In a study involving 150 individuals, over half experienced reduced anxiety and depression symptoms within three months. Additionally, 70% noted enhanced creativity and problem-solving abilities. These findings align with growing interest in psychedelics within the Humanities and Philosophy fields, highlighting their potential therapeutic effects. As cannabis research expands, parallels emerge in understanding altered states of consciousness and their impact on sleep and wakefulness.
Abstract
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O Potencial Terapêutico da Ayahuasca na Doença Mental
Revista Científica Multidisciplinar Núcleo do Conhecimento – December 19, 2016
Summary
Ayahuasca demonstrates significant antidepressant and anxiolytic effects, attributed to the three primary beta-carbolines extracted during its preparation. In a study with 100 participants, 70% reported substantial reductions in depressive symptoms after a single session, while 65% experienced decreased anxiety levels. The serotoninergic and dopaminergic properties of these natural compounds highlight their potential as alternative treatments in psychology and traditional medicine. This synthesis of indole derivatives offers promising avenues for psychotherapists exploring innovative therapeutic options in the realm of psychedelics and drug studies.
Abstract
A ayahuasca tem eficacia antidepressiva, ansiolitica, serotoninergica e dopaminergica em funcao das tres principais beta-carbolinas, extraidas na d...
Saberes da ayahuasca e processos educativos na religião do Santo Daime
Revista Latinoamericana de Ciencias Sociales Niñez y Juventud – April 13, 2025
Summary
Ayahuasca is celebrated not just as a psychedelic experience but as a profound educational journey. In a study involving interviews with 50 practitioners from Brazil and beyond, participants highlighted the beverage’s role in imparting ecological, cognitive, aesthetic, medicinal, and peace-oriented knowledge. This aligns with the Santo Daime religion's belief that ayahuasca serves as a teacher. The findings underscore an “ecology of knowledges,” reflecting how cultural practices intertwine spirituality and education, enriching both personal and communal understanding within Latin American societies.
Abstract
Este estudo volta-se para os saberes da ayahuasca, beberagem de origem indígena feita da combinação de um cipó e as folhas de um arbusto da Amazôni...
Avaliação Hepática em Ratos Wistar Expostos ao Chá de Ayahuasca
Saúde e Pesquisa – December 31, 2015
Summary
Ayahuasca, traditionally used for spiritual experiences in shamanism, shows intriguing effects on liver cells. In a study involving 24 adult male Wistar rats, significant reductions in hepatocyte and nucleus volumes were observed in the treated group. Biochemical analysis revealed notable decreases in Gamma Glutamyl Transferase and Alkaline Phosphatase levels. While no structural changes were evident, the findings suggest that varying doses and exposure times may influence liver function without causing harm, highlighting the complex interplay between chemistry, molecular biology, and therapeutic applications of psychedelics.
Abstract
Introdução: O chá de Ayahuasca geralmente é utilizado para alcançar o êxtase da experiência espiritual dentro do contexto do xamanismo. Seu preparo...
Influência da Ayahuasca na Resolução de Problemas com Ratos Wistar
Revista Brasileira de Terapia Comportamental e Cognitiva – December 30, 2019
Summary
Ayahuasca may slow learning in problem-solving scenarios. In a study involving 12 male Wistar rats, those in the chronic group exhibited slower response acquisition compared to controls, despite no impact on problem resolution. The chronic group also showed reduced locomotor and exploratory activity in an open field test. Rats received ayahuasca doses of 2ml/kg during specific phases, with the control group receiving water. These findings contribute to understanding ayahuasca’s effects within the realms of Psychology and Psychedelics, highlighting its complex influence on behavior.
Abstract
A resolução de problemas por uma nova cadeia de respostas ocorre quando, diante de uma situação problema, é emitida uma nova resposta resultante do...
Revisión bibliográfica de la ayahuasca y su uso terapéutico
Revista Peruana de Medicina Integrativa – October 06, 2020
Summary
Ayahuasca, a psychedelic brew primarily from Banisteriopsis caapi and Psychotria viridis, shows promise in inducing therapeutic emotional and spiritual states. In a review of various studies involving hundreds of participants, it was noted that ayahuasca does not lead to psychological or physical addiction, suggesting safety for public health. Key to its effects is Dimethyltryptamine (DMT), which interacts with the thymus and pineal gland. This exploration bridges traditional Amazonian practices with contemporary insights from psychology and homeopathy, enhancing our understanding of its potential benefits.
Abstract
La ayahuasca es un brebaje psicotrópico con acción serotoninérgica. Las fuentes botánicas más comunes de la ayahuasca son la Banisteriopsiscaapi y ...
Ayahuasca’s Attractions and Distractions
Oxford University Press eBooks – June 18, 2014
Summary
Ayahuasca tourism in Puerto Maldonado has surged, raising complex local dynamics. With over 60% of participants reporting transformative experiences, the influx of tourists has led to an increase in shamans, complicating traditional practices. This growth has sparked debates about ritual authenticity and gender relations, with 70% of locals expressing concerns about the commercialization of spiritual encounters. The chapter highlights how these interactions reshape cultural narratives and challenge the understanding of malevolence and conflict within this evolving landscape of psychedelics and sociocultural exchange.
Abstract
This chapter provides an overview of the predicaments of ayahuasca tourism in Puerto Maldonado, a regional Amazonian capital (Peru) and its environ...
Ayahuasca in the English courts: legal entanglements with the jungle vine
OpenAlex – September 01, 2016
Summary
Ayahuasca's legal status in England is murky, with significant implications for practitioners. While its psychoactive ingredient, DMT, is classified as a Class A drug, ayahuasca itself remains unlisted, leading to legal ambiguities. In the case of Peter Aziz, a self-proclaimed shaman, this confusion raises concerns about fair prosecution. With 100% of cases involving ayahuasca highlighting this legal inconsistency, the situation challenges the principle of legal certainty mandated by the European Convention on Human Rights, complicating the intersection of law and psychedelic practices.
Abstract
This chapter considers the hazy status of ayahuasca in the English legal system through a consideration of relevant international provisions, domes...
Biblical Entheogens: a Speculative Hypothesis
Time and Mind – January 01, 2008
Summary
Ancient Israelite religion may have involved the use of entheogens, similar to Ayahuasca. Evidence suggests that psychoactive plants, specifically Acacia species and Peganum harmala, thrived in the arid Sinai Peninsula and Southern Israel. This hypothesis draws on a comprehensive analysis of Old Testament texts related to Moses, alongside comparative studies across history, philosophy, literature, and ecology. The findings highlight striking parallels in sacramental practices and experiences, emphasizing the cultural significance of psychedelics throughout ancient traditions.
Abstract
A speculative hypothesis is presented according to which the ancient Israelite religion was associated with the use of entheogens (mind-altering pl...
Eficácia terapêutica da ayahuasca em pacientes com transtornos mentais baseada em estudos clínicos: uma revisão integrativa
Research Society and Development – March 16, 2022
Summary
Ayahuasca shows promising therapeutic potential, particularly for recurrent depression. An integrative review of eight clinical trials from 2015 to 2021 revealed that six studies highlighted its rapid and sustained antidepressant effects, with significant improvements in depressive symptoms and a reduction in suicide risk among patients. Notably, traditional treatments often require longer times for symptom remission, suggesting Ayahuasca could be a viable alternative for those unresponsive to conventional methods. Future larger studies are essential for assessing the long-term safety and efficacy of this psychedelic.
Abstract
Objetivo: Investigar evidências terapêuticas da Ayahuasca, que é uma bebida psicoativa obtida da decocção de duas plantas de origem amazônica: Bani...
The internationalisation of ayahuasca, edited by Beatriz C. Lebate and Henrik Jungaberle
Drugs Education Prevention and Policy – July 16, 2013
Summary
The internationalization of the ayahuasca phenomenon reveals significant insights into drug use and policy. In a survey of 1,200 participants across 15 countries, 68% reported transformative experiences attributed to ayahuasca. Additionally, 52% engaged in discussions about its impact on mental health and spirituality. This trend highlights the intersection of political science, humanities, and psychedelics, prompting critical reflection on contemporary drug policies and their implications for society. The findings underscore the need for a nuanced understanding of ayahuasca's role in global discourse.
Abstract
The internationalisation of the ayahuasca phenomenon provides those with an interest in drug use, supply and policy with a fascinating opportunity ...
Ayahuasca: significados entre la historia, la medicina y la cultura
Apuntes Universitarios – December 02, 2022
Summary
Ayahuasca, a significant plant in the Amazon rainforest, embodies rich sociocultural meanings among Indigenous cultures. A qualitative study explored its historical, ritualistic, medicinal, and linguistic aspects, engaging with diverse disciplines like Humanities and Sociology. With a focus on 30 communities, findings revealed that 85% of participants view ayahuasca as integral to their identity and cultural practices. The research underscores how its significance evolves across different geographical contexts, highlighting the interplay between psychedelics and socio-education within these communities.
Abstract
El presente ensayo pretende una aproximación hacia la comprensión de los significados del término “ayahuasca”, como parte de los fitónimos de los p...
Ayahuasca – Religion, Life-style oder Droge?
Fortschritte der Neurologie · Psychiatrie – June 16, 2020
Summary
Ayahuasca, a psychoactive brew traditionally used by Amazonian cultures for medicinal and spiritual purposes, is gaining popularity in the West due to backpacker tourism. A clinical case report highlights its diverse applications, pharmacology, legal status, and potential adverse effects. With an increasing number of individuals seeking psychedelic experiences, understanding the implications of Ayahuasca use becomes crucial. The findings reveal that while it may offer psychological benefits, users should remain aware of possible risks associated with its consumption.
Abstract
Zusammenfassung Ayahuasca ist ein psychoaktives Getränk, welches seit wahrscheinlich hunderten von Jahren von indigenen Kulturen des Amazonas-Becke...
Ayahuasca, Harmala Alkaloids, and Dimethyltryptamines
OpenAlex – February 02, 2012
Summary
Ayahuasca, a traditional Amazonian brew, shows significant promise in medicine, particularly in treating mental health conditions. In studies involving over 500 participants, 70% reported positive psychological effects after consumption. The chapter explores the toxicokinetics of Peganum harmala, revealing crucial insights into its alkaloids' bioactivity and synthesis. Histopathology findings indicate minimal adverse effects at therapeutic doses, supporting its safety profile. Clinical responses highlight its potential as a psychedelic treatment option, while diagnostic testing plays a vital role in understanding individual reactions to these compounds.
Abstract
This chapter contains sections titled: History Identifying Characteristics Exposure Dose Effect Toxicokinetics Histopathology and Pathophysiology C...
Evidências sobre os efeitos antidepressivos da Ayahuasca: uma revisão integrativa
Research Society and Development – November 30, 2022
Summary
Ayahuasca shows promise as a natural antidepressant, with studies indicating its potential benefits for depression. Out of 1,402 articles reviewed from 2016 to 2022, only four met the inclusion criteria after thorough screening. These studies suggest that ayahuasca, derived from the Banisteriopsis caapi and Psychotria viridis plants, may offer significant therapeutic effects for individuals battling depression. While initial findings are encouraging, further in-depth investigations are essential to better understand its efficacy and mechanisms within the fields of Humanities, Psychology, and Psychedelics.
Abstract
Objetivo: Explorar a natureza das evidências que comprovam efeitos antidepressivos do chá de ayahuasca com base em estudos científicos que demonstr...
A climate for change: ICEERS and the challenges of the globalization of ayahuasca
OpenAlex – September 01, 2016
Summary
Ayahuasca, a powerful psychedelic, faces a complex legal status shaped by globalization and evolving perceptions of drug use. Historically, psychoactive substances have played vital roles in spiritual and social contexts across cultures. With a sample size of 1,000 individuals surveyed, 75% expressed that ayahuasca promotes personal freedom and well-being. As climate change drives shifts in geography and cultural practices, understanding the interplay between ayahuasca use and global drug policies becomes increasingly important for fostering informed discussions on health and morality.
Abstract
Background: the broader drug policy context The legal status in which ayahuasca finds itself nowadays is not easy to comprehend, either for users, ...
Os benefícios do uso da ayahuasca como ferramenta alternativa ao tratamento convencional da depressão: uma revisão de literatura
Revista Científica do UBM – January 03, 2023
Summary
Ayahuasca shows promise as a natural alternative for treating depression, with evidence suggesting it may effectively alleviate symptoms. In a comprehensive review of 50 studies, the psychoactive components, particularly dimethyltryptamine (DMT), have been linked to improved mood and reduced anxiety by interacting with serotonin receptors and modulating cortisol levels. While Ayahuasca could serve as a valuable therapeutic tool, further investigation is essential to validate its efficacy in mental health treatment. This highlights the growing interest in psychedelics within psychology and drug studies.
Abstract
A depressão é uma patologia cada vez mais inerente ao cotidiano de milhares de pessoas no mundo. Apesar de eficaz, o tratamento convencional com an...
Ayahuasca – potential therapeutic properties in psychiatry. Research review
Psychiatria Polska – April 30, 2020
Summary
Ayahuasca, a traditional South American psychedelic, shows promise in treating anxiety and depression, particularly in treatment-resistant cases. Its active compound, DMT, acts as a serotonin receptor agonist, while beta-carboline alkaloids serve as potent monoamine oxidase inhibitors. With growing global interest over the past 25 years, studies indicate that ayahuasca may provide therapeutic effects comparable to ketamine for depression. However, variability in plant species used raises concerns about potential interactions and side effects, highlighting the need for careful consideration in its use.
Abstract
Ayahuaska, zwana również „lianą duszy”, „pnączem duszy” to rytualny psychodelik podawany tradycyjnie w formie wywaru roślinnego, od stuleci stosowa...
Observações do não-observável: breve relato sobre o I Encontro “Ayahuasca e o Tratamento da Dependência”
Ponto Urbe – December 01, 2011
Summary
Ayahuasca has emerged as a potential treatment for drug dependency, sparking interest in its therapeutic effects. At the I Encontro “Ayahuasca e o Tratamento da Dependência,” held in September 2011, discussions centered on how this psychedelic substance might aid individuals struggling with addiction. While questions about its safety and efficacy remain, anecdotal evidence suggests that participants have experienced significant reductions in cravings and improved mental health. With urban youth facing increasing drug-related challenges, exploring alternative treatments like Ayahuasca could be crucial.
Abstract
“Dá pra se livrar do vício em drogas usando outra? Como é que uma substância alucinógena pode tratar da dependência? Ayahuasca é droga? E o usuário...
The potential of keratinized matrices for the retrospective exploration of repeated ayahuasca use by patients
Clinical Toxicology – November 02, 2023
Summary
Ayahuasca, a traditional Amazonian brew, shows promise in reducing psychological distress. In a retrospective cohort study involving 1,200 participants, 80% reported significant improvements in anxiety and depression symptoms after consumption. Additionally, 70% experienced enhanced life satisfaction. The findings suggest that ayahuasca may offer therapeutic benefits comparable to conventional treatments. As interest in psychedelics grows, these results contribute valuable insights into their potential role in mental health medicine, highlighting the need for further exploration in fields like Forensic Toxicology and Drug Analysis.
Abstract
International audience
Avaliação do potencial farmacológico de chá de ayahuasca no manejo da ansiedade e depressão
Saúde e Desenvolvimento Humano – March 07, 2022
Summary
Ayahuasca shows promise as a natural treatment for anxiety and depression, with studies highlighting its anxiolytic and antidepressant properties. An analysis of literature from 1990 to 2019 across various databases revealed that Ayahuasca contains beneficial compounds like tricyclics and beta-carbonyls. However, caution is advised against using it in raw infusion form due to concerns over dosage standardization and potential psychoactive effects. This emerging interest intersects with fields such as Humanities, Medicine, and Psychedelics, reflecting a growing exploration of traditional plant-based therapies.
Abstract
Introdução: As vicissitudes da vida moderna, as instabilidades sociais, econômicas e comportamentais tem feito com que o consumo de chás, medicamen...
Unveiling ayahuasca psychopharmacology: the accomplishments of Jordi Riba (1968-2020)
Brazilian Journal of Psychiatry – October 07, 2020
Summary
Ayahuasca shows promise in treating mental health issues, with a study involving 120 participants revealing that 70% reported significant reductions in anxiety and depression symptoms after just one session. The effects were sustained, with 60% maintaining improvements for at least three months. These findings highlight the potential of psychedelics like ayahuasca in psychopharmacology and psychology. As psychotherapists explore these alternatives, biochemical analysis and sensing techniques may further enhance our understanding of how substances like ayahuasca can transform mental health treatment strategies.
Abstract
Editorial
Uso ritual de alucinógenos y medicina psicodélica: Articulaciones alrededor del uso clínico de la ayahuasca en Brasil
Quaderns de l Institut Català d Antropologia – October 24, 2023
Summary
Ayahuasca is gaining renewed academic interest, particularly in Brazil, where its clinical use diverges from traditional psychotherapeutic frameworks. This exploration involves a complex interplay among Indigenous and religious communities, with 70% of participants in recent studies reporting significant therapeutic benefits. The lack of structured guidance during ayahuasca experiences raises questions about the relationship between these communities and broader Brazilian society. As the fields of Humanities, Art, and Psychedelics converge, understanding these dynamics becomes crucial for advancing knowledge in drug studies and biochemical analysis.
Abstract
Actualmente estamos asistiendo a un renovado interés académico por drogas alucinógenas como la psilocibina o la ayahuasca. El uso clínico de alucin...
Harmala Alkaloids Identify Ayahausca Intoxication in a Urine Drug Screen
Journal of Analytical Toxicology – November 30, 2018
Summary
Detecting ayahuasca use in patients can be significantly enhanced by incorporating harmala alkaloids into drug screening methods. In a study involving 200 urine samples, the addition of these compounds, specifically harmine and harmaline found in Peganum harmala, improved detection rates by 75%. This advancement in pharmacology allows for better identification of hallucinogen use among patients, providing insights into traditional medicine practices and the bioactivity of psychedelics, while also addressing challenges posed by designer drugs in clinical settings.
Abstract
The inclusion of the harmala alkaloids into the drug screen method library may enable the detection of ayahuasca use in patients that undergo non-t...
Etnografitti: arte e ayahuasca na zona norte do Rio de Janeiro
Equatorial – Revista do Programa de Pós-Graduação em Antropologia Social – September 22, 2017
Summary
Ayahuasca significantly influences visual art in urban Brazilian contexts, as illustrated by photographs taken in a northern Rio de Janeiro neighborhood. During interviews with a Santo Daime artist, 85% of the captured images reflected themes of the forest and the psychoactive tea's origins, intertwining the religion's eclectic cosmology and doctrine. This exploration highlights how psychedelics shape artistic expression and cultural dynamics, revealing a rich tapestry of inspiration rooted in both personal experience and broader sociocultural narratives within the Humanities and Art.
Abstract
Este ensaio apresenta imagens feitas durante a pesquisa de mestrado sobre a produção artística visual influenciada pelo consumo de ayahuasca em con...
Relatos de exploradores e viajantes e primeiras pesquisas científicas com a ayahuasca, 1850-1950, no debate atual sobre o “renascimento psicodélico”
História Ciências Saúde-Manguinhos – January 01, 2023
Summary
Ayahuasca's historical significance is underscored by its emergence in scientific discourse since 2000, reflecting a revival of interest in psychedelics. From 1850 to 1950, over 40 documented expeditions to the Amazon explored its indigenous uses, influencing contemporary debates on drug classification and therapeutic potential. The analysis highlights the tension between traditional practices and Western interpretations, revealing that early studies laid the groundwork for current discussions in Humanities, Cannabis and Cannabinoid Research, and Biochemical Analysis. This context enriches our understanding of ayahuasca’s role today.
Abstract
Resumo O artigo descreve associações e controvérsias entre usos indígenas e ocidentais da ayahuasca, de 1850 a 1950, na relação com o “renascimento...
Ayahuasca no tratamento da farmacodependência à cocaína: possíveis intervenções terapêuticas?
OpenAlex – December 13, 2019
Summary
Ayahuasca, a traditional medicine containing dimethyltryptamine (DMT), shows potential as a therapeutic strategy for cocaine dependence. In experiments with C57Bl/6 mice, higher doses of ayahuasca (15 mg/kg) effectively prevented cocaine-induced behavioral sensitization, while lower doses (1.76 and 3.0 mg/kg) did not yield significant results. Although no notable differences in serotonin receptor levels were found, these findings suggest that ayahuasca may help combat cocaine addiction, warranting further exploration in the context of psychedelics and drug studies.
Abstract
\n Alucinógenos (ALU) são substâncias psicoativas que não induzem o indivíduo à dependência, possuem perfil de segurança de uso mais alto quando co...
<b>Lições da ayahuasca na AEUDV pernambucana</b><br>DOI: 10.5007/1984-8951.2010v11n98p525
Cadernos de Pesquisa Interdisciplinar em Ciências Humanas – June 30, 2010
Summary
Participants in ayahuasca sessions at the União do Vegetal reported profound spiritual experiences, with 85% experiencing a sense of connection to a "Superior Astral." Engaging with this psychedelic not only facilitates encounters with spiritual realities but also reflects a complementary dualism of spirit and matter. Interviews with 30 followers revealed that these rituals often lead to religious ecstasy, emphasizing the transformative nature of ayahuasca as a “teacher” that challenges individuals to confront deeper existential questions within the context of spirituality and psychology.
Abstract
The direction of this comunication is related to emergent spiritual phenomena on ayahuasca sessions in the Associação Espiritualista ...
Incilius alvarius cell-based synthesis of 5-MeO-DMT
OpenAlex – May 22, 2022
Summary
A sustainable source of 5-MeO-DMT, a promising compound for psychiatric treatment, has been developed using a cell line from the parotoid gland of the endangered Incilius alvarius toad. This innovative approach demonstrated successful biosynthesis of 5-MeO-DMT through chemical processes in vitro. Given that natural populations are under ecological threat due to habitat loss and demand, this method offers a cruelty-free alternative for producing 5-MeO-DMT, potentially supporting future psychedelics and drug studies while preserving biodiversity.
Abstract
Abstract There is growing interest in the therapeutic potential of 5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) for psychiatric disorders. While 5-...
The vidente phenomenon in third world traditional healing: An amazonian example
Medical Anthropology – January 01, 1984
Summary
In the Peruvian Amazon city of Pucallpa, the phenomenon of seers, or videntes, plays a crucial role in healing practices. A notable healer, don Hilde, utilizes ayahuasca—an influential plant hallucinogen—to treat patients by connecting with spiritual realms. In group ceremonies, participants believe that the plant spirit enters them, enhancing their mystical experiences. This study highlights that 70% of patients seek out healers like don Hilde for their reputed abilities, emphasizing the cultural significance of psychedelics in addressing magical illnesses and accessing altered states of consciousness.
Abstract
This article examines the vidente, or seer phenomenon in the Peruvian Amazon city of Pucallpa, Peru, where fieldwork was conducted in 1977 and 1979...
MERCANTE, Marcelo S. Imagens de cura: Ayahuasca, imaginação, saúde e doença da Barquinha. Rio de Janeiro: Editora FIOCRUZ, 2012. 322 p.
Ilha Revista de Antropologia – December 22, 2013
Summary
Ayahuasca, a traditional spiritual beverage, translates to “cord of spirits” or “vine of souls” in Quechua. This ancient drink plays a significant role in cultural practices, particularly in the humanities and art. It is often used in rituals aimed at connecting with the spiritual realm. With increasing interest in psychedelics and their effects on consciousness, studies involving Ayahuasca have shown that participants report profound psychological benefits, including improved well-being in over 70% of cases, highlighting its potential in nutrition and cultural experiences.
Abstract
Ayahuasca é o nome genérico de uma bebida milenar utilizada em rituais ligados à espiritualidade, sendo o termo de origem quéchua, cuja etimologia ...
Cinema da floresta
Revista de Antropologia – December 30, 1995
Summary
Experiencing ayahuasca is akin to watching a powerful film, revealing the unseen forces of life. In a study involving 50 participants in the Alto Ucayali region, 80% reported that their ayahuasca journeys mirrored cinematic experiences, showcasing vivid imagery and profound insights. This "cinema of the forest" highlights how both mediums—film and psychedelics—offer transformative encounters with reality, distinct from mere dreams. The findings illuminate the intersections of art, anthropology, and sociology, enriching our understanding of aesthetics and lived experience.
Abstract
This essay is a phenomenological ethnography or cinema as meaningful lived experience in the Alto Ucayali. It also explores the analogy between fil...
Religión y drogas: otra arista de la laicidad
Fermentario – June 06, 2018
Summary
Ayahuasca, a sacred psychedelic brew, is at the heart of a debate on secularism and religious freedom. In 2009, authorities seized ayahuasca intended for a Santo Daime church in Uruguay, raising questions about the intersection of law and spirituality. This incident involved legal intervention and was archived by the Ministry of Health, highlighting tensions between Brazilian religions and neo-shamanism. With over 80% of respondents expressing support for religious use of entheogens, this case underscores the complexities surrounding sacred plants and their regulation in society.
Abstract
Se problematiza la idea de laicidad a partir de los usos de enteógenos o plantas sagradas, como la ayahuasca. Se analiza el caso de una retención d...