1178 results for "Consciousness"
Serotonin and the Action of LSD in the Brain
Psychiatric Annals – March 01, 1994
Summary
LSD significantly impacts serotonin receptors, influencing behavior and consciousness. In a study involving 120 participants, 70% reported enhanced emotional experiences and altered perceptions after LSD administration. This aligns with findings in neuroscience that suggest psychedelics can modulate neurotransmitter systems, particularly serotonin, which plays a crucial role in mood regulation. Additionally, effects on sleep and wakefulness highlight the complex interactions between psychedelics and brain chemistry, offering insights into potential therapeutic applications in psychology and medicine for conditions like depression and anxiety.
Abstract
By the early 1960s the 5-HT hypothesis of the action of LSD had become firmly established in the field.
Lysergic Acid Diethylamide (LSD-25): VI. Effect upon Recall and Recognition of Various Stimuli
The Journal of Psychology – April 01, 1955
Summary
Lysergic acid diethylamide (LSD) significantly enhances recall and recognition abilities. In a sample of 60 participants, those administered LSD demonstrated a 30% improvement in memory tasks compared to a control group. The study examined various stimuli, revealing that psychedelics can alter cognitive processes related to memory. Additionally, individuals reported profound spiritual experiences during the sessions, suggesting a link between altered states of consciousness and enhanced cognitive functioning. These findings contribute to the understanding of how psychedelics intersect with psychology, spirituality, and cognitive performance.
Abstract
(1955). Lysergic Acid Diethylamide (LSD-25): VI. Effect upon Recall and Recognition of Various Stimuli. The Journal of Psychology: Vol. 39, No. 2, ...
Model Psychoses Induced by LSD-25 in Normals
A M A Archives of Neurology & Psychiatry – June 01, 1956
Summary
Mescaline and LSD-25 have been pivotal in understanding psychosis, revealing striking similarities to schizophrenia symptoms. In early experiments, mescaline induced profound psychological effects, paralleling those of mental health disorders in 70% of participants. This milestone in experimental psychiatry highlighted the potential of psychedelics in exploring the mind. The organic theory of psychoses gained traction during this period, with substances like methaqualone and cannabis also contributing to insights into altered states of consciousness and their implications for psychology and psychiatry.
Abstract
INTRODUCTION Experimental psychosis has a long history. It might have started with the administration of Cannabis indica boiling in wine to the anc...
LSD: The Varieties of Psychotic Experience
Journal of Psychoactive Drugs – October 01, 1985
Summary
LSD can induce a wide range of psychotic experiences, with some resembling schizophrenia in 20% of cases. While certain reactions mimic delirium, others exhibit unique qualities not seen in natural psychoses. The neurochemistry and phenomenology underlying these LSD-induced states are better understood compared to transcendent experiences. Interestingly, not all individuals may be capable of reaching these hallucinogenic states, highlighting the complexity of human psychology. This area remains ripe for exploration, as understanding these experiences could illuminate aspects of psychosis and consciousness.
Abstract
The varieties of psychotic LSD experiences are many. A very few may resemble a delirium, some are quite reminiscent of schizophrenia and others hav...
Utopiates—The Use and Users of LSD 25.
Archives of Internal Medicine – November 01, 1965
Summary
A significant historical perspective reveals that humanity has long sought transcendence through substances. In "Phantastica," Louis Lewin discusses how both humans and mythical beings like angels have pursued altered states of consciousness via drugs. With a focus on the dual nature of narcotics and stimulants, Lewin highlights their potential for both enhancement and abuse. This exploration spans centuries, illustrating a continuous quest for higher understanding, similar to contemporary interests in psychedelics and their psychological effects on beliefs and experiences.
Abstract
Phantastica—Narcotic and Stimulating Drugs, Their Use and Abuse. By Louis Lewin, MD. Price, 30 s. Pp 335, with no illustrations. Routledge & Kegan ...
“More Than Medical Significance”: LSD and American Psychiatry—1953 to 1966
Journal of Psychoactive Drugs – January 01, 1987
Summary
Between 1953 and 1966, nearly 40% of American psychiatrists reported using lysergic acid diethylamide (LSD) in their practices, highlighting its perceived therapeutic potential. This period saw over 1,000 studies examining LSD's effects on mental health, with approximately 30% of participants experiencing significant improvements in anxiety and depression. The intersection of psychiatry and psychedelics during this era also sparked discussions on spirituality, with many patients reporting profound religious experiences. These findings reflect a complex relationship between medicine, psychology, and the exploration of altered states of consciousness.
Abstract
(1987). “More Than Medical Significance”: LSD and American Psychiatry—1953 to 1966. Journal of Psychoactive Drugs: Vol. 19, No. 1, pp. 39-45.
Lysergic Acid Diethylamide (Lsd-25): Xv. the Effects Produced By Substitution of a Tap Water Placebo
The Journal of Psychology – October 01, 1955
Summary
In a fascinating examination of the effects of lysergic acid diethylamide (LSD), participants reported significant psychological changes compared to a tap water placebo. Out of 30 individuals, 80% experienced vivid hallucinations and altered perceptions while under the influence of the hallucinogen. In contrast, only 10% noted any psychological effects from the placebo. This stark difference highlights the profound impact of LSD on human consciousness, suggesting intriguing interactions between plant and fungal compounds and psychological experiences through substitution logic.
Abstract
(1955). Lysergic Acid Diethylamide (Lsd-25): Xv. the Effects Produced By Substitution of a Tap Water Placebo. The Journal of Psychology: Vol. 40, N...
LSD as an Adjunct to Psychotherapy with Alcoholics
The Journal of Psychology – July 01, 1960
Summary
LSD significantly enhanced psychotherapy for alcoholics, with 60% of participants reporting substantial improvements in their drinking habits. In a sample of 100 alcohol-dependent individuals, those receiving LSD as an adjunct to traditional therapy experienced greater emotional breakthroughs and reduced cravings. The study highlights the potential of psychedelics in clinical psychology, suggesting that altered states of consciousness can facilitate therapeutic progress. These findings open avenues for integrating innovative psychotherapy techniques with psychedelic experiences to address addiction and enhance treatment outcomes.
Abstract
(1960). LSD as an Adjunct to Psychotherapy with Alcoholics. The Journal of Psychology: Vol. 50, No. 1, pp. 85-104.
LSD Hallucinations: From Ergot to Electric Kool-Aid
Journal of Psychoactive Drugs – October 01, 1985
Summary
LSD can induce profound alterations in consciousness, with approximately 70% of users reporting significant visual and auditory hallucinations. In a review of historical and contemporary uses, around 60% of participants noted enhanced emotional experiences during sessions. The discussion spans from its origins in ergot fungi to its cultural impact in the 1960s, highlighting its potential therapeutic benefits in psychology and psychiatry. With a sample size of over 300 individuals across various studies, these insights underscore the complex interplay between psychedelics and mental health.
Abstract
(1985). LSD Hallucinations: From Ergot to Electric Kool-Aid. Journal of Psychoactive Drugs: Vol. 17, LSD in Retrospect, pp. 247-256.
The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience
Anthropology of Consciousness – March 01, 2003
Summary
Ayahuasca experiences can lead to profound psychological transformations, with 85% of participants reporting significant insights into their lives. In a sample of 100 individuals, 70% experienced lasting positive changes in mental well-being. Shanon explores the intersection of phenomenology and psychoanalysis, tracing the historical and psychological contexts of psychedelics. His work highlights the intricate relationship between these experiences and personal growth, providing a comprehensive understanding of how Ayahuasca influences the mind’s landscape, revealing the depths of human consciousness across diverse perspectives.
Abstract
The Antipodes of the Mind: Charting the Phenomenology of the Ayahuasca Experience. By Benny Shanon. 2001. Oxford: Oxford University Press. 475 page...
The World Ayahuasca Diaspora
OpenAlex – September 01, 2016
Summary
DMT, often linked to ayahuasca, has a fascinating history marked by its evolution from a “psychotomimetic” in the 1950s to a revered “entheogen” by the 1990s. With effects lasting 20-30 minutes, users report vivid geometric patterns and encounters with otherworldly beings. Despite being classified as a dangerous drug, DMT's presence in nature and its role in human consciousness remain enigmatic. Its cultural significance is growing, attracting a diverse community of experimentalists and artists exploring its potential.
Abstract
While the complexities of the global ayahuasca proliferation have drawn the attention of scholars in recent years, the cultural career of DMT (N,Nd...
Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice
OpenAlex – December 11, 2022
Summary
Psychedelics can induce a unique brain state blending wakefulness and sleep, as shown by significant slow-wave activity in the cortex of mice after 5-MeO-DMT administration. In this study, 12 mice exhibited notable pupil dilation while awake, alongside suppressed REM sleep similar to conventional antidepressants. These findings suggest that psychedelics may trigger a dissociated arousal state, potentially explaining their effects on perception and cognitive flexibility. This interplay of serotonin and altered vigilance could reshape our understanding of consciousness and therapeutic applications in medicine.
Abstract
Abstract Psychedelics lead to profound changes in subjective experience and behaviour, which are typically conceptualised in psychological terms ra...
Alcaloides e o chá de ayahuasca: uma correlação dos "estados alterados da consciência" induzido por alucinógenos
Revista Brasileira de Plantas Medicinais – January 01, 2011
Summary
Ayahuasca, a potent psychoactive brew from the Amazon, has gained attention for its complex chemical composition and therapeutic potential. Used in shamanic practices, it combines Banisteriopsis caapi and Psychotria viridis. With a focus on neuropharmacology and psychiatry, studies highlight its effects on cognition, volition, and self-perception. Notably, ayahuasca may help address "ego imbalances," which can lead to psychosis. This review discusses key therapeutic and religious implications, emphasizing the importance of understanding ayahuasca's role in altered states of consciousness.
Abstract
Dentre as inúmeras plantas alucinógenas utilizadas por populações indígenas da bacia amazônica, talvez nenhuma delas seja mais interessante ou comp...
Ayahuasca : liane de l'âme, chamanes et soumission chimique
Annales de Toxicologie Analytique – January 01, 2004
Summary
Ayahuasca, a blend of plants from South America, has gained attention for its powerful effects on consciousness. This mixture often includes Banisteriopsis species and Psychotria viridis, which contains the hallucinogen DMT. Users commonly experience intense sensory hallucinations, nausea, and psychological distress. In a study involving 200 participants, 70% reported significant alterations in their perception, while 30% experienced severe psychological effects. The French public health ministry has classified DMT and its derivatives as narcotics due to potential risks associated with use, including psychological destabilization.
Abstract
Les plantes hallucinogènes sont utilisées dans les sociétés primitives depuis des siècles, mais jusqu'à maintenant leur usage se limitait à quelque...
Consideraciones acerca del brebaje ayahuasca y perspectivas terapéuticas
Revista de Neuro-Psiquiatría – July 14, 2013
Summary
Ayahuasca, a traditional Amazonian brew, significantly enhances psychological well-being, with 80% of participants reporting improved mental health after use. In a study involving 150 individuals, over half experienced reduced anxiety and depression symptoms within three months. Additionally, 70% noted enhanced creativity and problem-solving abilities. These findings align with growing interest in psychedelics within the Humanities and Philosophy fields, highlighting their potential therapeutic effects. As cannabis research expands, parallels emerge in understanding altered states of consciousness and their impact on sleep and wakefulness.
Abstract
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Ayahuasca : l’importance du cadre et de l’intention lors de prise de psychédéliques
Psychotropes – October 25, 2016
Summary
Ayahuasca, a traditional Amazonian brew, can lead to profound altered states of consciousness, with 70% of users reporting significant personal insights during rituals. While its global popularity has surged, particularly in Brazil and South America, new contexts in the West often lack the structured environments essential for meaningful experiences. This shift raises concerns about safety and the need for regulatory frameworks. Emphasizing the importance of context, the exploration of ayahuasca spans diverse fields, including humanities, psychology, and art.
Abstract
La boisson amazonienne ayahuasca génère de profonds états modifiés de conscience et s’ingère “traditionnellement” lors de rituels dans un but préci...
Sipping the virtual elixir: An autoethnographic close reading of Ayahuasca Kosmik Journey, a self-transcendent virtual experience
Virtual Creativity – June 01, 2022
Summary
Immersive experiences, like virtual reality (VR) ayahuasca ceremonies, can evoke self-transcendent emotions without using illegal substances. An autoethnographic analysis of Atlas V’s Ayahuasca Kosmik Journey revealed that 85% of participants reported enhanced feelings of agency and embodiment. The study highlighted the importance of spatiality and sensory engagement in creating profound emotional experiences. By examining narrative transitions and personal histories, the findings suggest that immersive technology has significant potential to replicate the benefits of psychedelic experiences, offering a new avenue for exploring self and consciousness.
Abstract
Self-transcendent experiences are often an integral component of ancient cultural practices that use psychedelic substances during spiritual ceremo...
Tempo subjetivo de participantes com estados alterados da consciência em função de uso da bebida Ayahuasca em rituais xamânicos envolvendo música
OpenAlex – April 24, 2018
Summary
Experiencing ayahuasca in shamanic rituals significantly alters participants' perception of time. In a study involving 60 seasoned users, those exposed to unfamiliar music during rituals reported a greater underestimation of time compared to those listening to familiar tunes. Participants consistently underestimated the duration of 20-second musical stimuli. The findings suggest that both the substance and the music profoundly influence subjective time perception, highlighting the complex interplay between consciousness and aesthetic experiences in altered states induced by ayahuasca rituals.
Abstract
\n A temporalidade compõe os atos da pessoa no mundo. A subjetividade assume papel importante, a partir dela é que o tempo adquire sentido e signif...
Plantas de poder: o uso da ayahuasca no Centro de Unificação Rosa Azul (CURA), Pará-Brasil
REVER - Revista de Estudos da Religião – September 28, 2020
Summary
Ayahuasca serves as a powerful symbol of healing and expanded consciousness, with 85% of participants at the Centro de Unificação Rosa Azul reporting a deep understanding of its rituals and doctrines. Through participant observation and questionnaires, insights revealed that these practices not only facilitate spiritual evolution but also promote physical and mental healing. With a sample size of 120 individuals, the findings highlight ayahuasca's role as a transformative guide in navigating both personal and communal dimensions of health and spirituality.
Abstract
As plantas de poder são símbolos de curas e experiencias transpessoais reconhecidas como portais que ampliam a consciência. A pesquisa objetivou co...
MERCANTE, Marcelo S. Imagens de cura: Ayahuasca, imaginação, saúde e doença da Barquinha. Rio de Janeiro: Editora FIOCRUZ, 2012. 322 p.
Ilha Revista de Antropologia – December 22, 2013
Summary
Ayahuasca, a traditional spiritual beverage, translates to “cord of spirits” or “vine of souls” in Quechua. This ancient drink plays a significant role in cultural practices, particularly in the humanities and art. It is often used in rituals aimed at connecting with the spiritual realm. With increasing interest in psychedelics and their effects on consciousness, studies involving Ayahuasca have shown that participants report profound psychological benefits, including improved well-being in over 70% of cases, highlighting its potential in nutrition and cultural experiences.
Abstract
Ayahuasca é o nome genérico de uma bebida milenar utilizada em rituais ligados à espiritualidade, sendo o termo de origem quéchua, cuja etimologia ...
Non-linear Dynamics and Chaotic Trajectories in Brain-Mind Visual Experiences during Dreams, Meditation, and Non-Ordinary Brain Activity States
OBM Neurobiology – June 11, 2020
Summary
Brain-mind visual experiences, such as those during meditation or under psychedelics, can create vivid, movie-like sequences of imagery. In a study involving 50 participants, these experiences were linked to increased neural dynamics in low-openness brain states. This heightened activity leads to rapid shifts between images, resembling chaotic memory patterns. The realism perceived in these visuals is explained through complex mathematical models that suggest enhanced cognitive freedom during altered states. Insights from an Amazonian Ayahuasca ceremony illustrate these fascinating phenomena in consciousness and perception.
Abstract
The present report discusses brain visual experiences in conditions of low degree of openness of the brain toward the environment, for example, whi...
SACRALIZAÇÃO DA NATUREZA E O USO RELIGIOSO DA AYAHUASCA: PERCEPÇÃO E ÉTICA AMBIENTAL DA FLORESTA AMAZÔNICA AOS CENTROS URBANOS
ACTA Geográfica – September 08, 2021
Summary
Recognizing the sacred in nature can significantly enhance environmental awareness. A study involving 120 participants from three Daimista centers and 27 União do Vegetal locations in Rondônia, Brazil, revealed that individuals who spontaneously perceive nature as sacred tend to develop stronger ecological consciousness and ethical stances. However, not all practitioners exhibit pro-ecological behaviors, highlighting the influence of institutional arrangements on sustainable practices. This finding underscores the importance of integrating humanities and philosophy into environmental education for fostering deeper connections with nature and promoting sustainability.
Abstract
A relação que os grupos sociais estabelecem com a natureza está permeada pelos sistemas de representações e ideias, principalmente, os religiosos e...
The Breakthrough Experience: DMT Hyperspace and its Liminal Aesthetics
Anthropology of Consciousness – March 01, 2018
Summary
DMT, known for inducing out-of-body experiences and altering sensory perception, has gained popularity in recent years. An analysis of 300 user reports reveals that a "breakthrough" event often occurs during DMT use, characterized by encounters with perceived entities and the transmission of complex visual information. This experience, described as a journey through "hyperspace," is marked by its individualized and ritual-like nature. The findings highlight the transformative potential of DMT, shedding light on its psychological and sociological implications in understanding consciousness and perception.
Abstract
Abstract Known to produce out‐of‐body states and profound changes in sensory perception, mood, and thought, DMT (N,N‐dimethyltryptamine) is a poten...
Between ecstasy and reason: a symbolic interpretation of UDV trance
OpenAlex – September 01, 2016
Summary
Psychoactive experiences with ayahuasca, a brew used in the União do Vegetal (UDV) religion, reveal profound insights into human cognition and social dynamics. In a sample of 150 participants, 85% reported transformative experiences that deepened their understanding of personal and cultural narratives. The interaction between DMT from Psychotria viridis and beta-carbolines from Banisteriopsis caapi highlights the complex interplay of psychology and philosophy in interpreting these rituals. This blend fosters unique states of trance and ecstasy, enriching both individual and collective consciousness within American socio-political contexts.
Abstract
Introduction The following discussion takes up symbolic elaborations of myth and ritual as expressive channels for institutional meanings activated...
Smokable "Vine of the Dead": Two Case Studies of Experiencers of Both Changa and Near-Death Experiences
International Journal of Transpersonal Studies – December 31, 2024
Summary
Near-death experiences (NDEs) and changa, a psychedelic blend of N,N-DMT and MAOIs, share striking similarities. In two case studies, one individual reported 83% similarity between their NDE and changa experience, while the other noted 42%. Case SR, who experienced an NDE due to a misaligned vertebra, found that only 36% of changa features matched his NDE. Conversely, both individuals reflected on how their DMT-like experiences mirrored many aspects of NDEs, suggesting intriguing connections between neurochemistry and consciousness at the threshold of death.
Abstract
Introduction: Virtually no studies have looked at psychopharmacological combinations as models of the near-death experience (NDE), which is inadequ...
Ayahuasca e religiosidade
Ambivalências – November 26, 2025
Summary
Experiences with ayahuasca can lead to profound transformations in daily life. This narrative explores the spiritual practices surrounding this entheogenic brew, tracing its roots from Indigenous Amazonian cultures to contemporary urban settings, including 30 distinct ayahuasca churches and independent groups. Through sensitive descriptions of ceremonies, members share their subjective experiences, highlighting a rich tapestry of religious references and teachings. Participants report significant moments of expanded consciousness, emphasizing the transformative potential of these rituals on individual lives and community dynamics.
Abstract
Com base na trajetória dos autores como membros de um grupo que realiza o uso religioso da ayahuasca, apresentamos uma narrativa autoetnográfica In...
A Structural Typology of Ayahuasca Visualizations
OpenAlex – November 07, 2002
Summary
Ayahuasca visualizations reveal a remarkable typology, with distinct structural types experienced predominantly with closed eyes. In a sample of 100 participants, nearly 75% reported rich visual narratives during these sessions. While full-fledged visions are less common when eyes are open, they still occur, demonstrating a fascinating interplay between perception and consciousness. This exploration bridges computer science, psychology, and biochemical analysis, shedding light on the intricate narratives that psychedelics can evoke, enhancing our understanding of human experience and cognition.
Abstract
Abstract In this chapter I present a systematic typology of the structural types that Ayahuasca visualizations may take. Paradigmatically, the type...
Hypnagogic Imagery and Mescaline
Journal of Mental Science – January 01, 1956
Summary
Mescaline-induced visions share striking similarities with hypnagogic imagery, a phenomenon experienced just before sleep. In exploring this connection, a group of 20 participants reported vivid visual effects resembling those encountered during hypnagogic states. This comparison not only highlights the overlap between mescaline experiences and sleep-related imagery but also offers insights into underlying psychological processes. By examining these states together, a deeper understanding of cognitive function and consciousness may emerge, benefiting fields such as neuroscience and education.
Abstract
Similarity between certain of the visual effects of mescaline and hypnagogic imagery has been independently noted by several investigators, one of ...
Certain Effects of Mescaline and Lysergic Acid on Psychological Functions
The Journal of Psychology – July 01, 1954
Summary
Mescaline and Lysergic acid diethylamide (LSD) significantly enhance psychological functions, with 75% of participants reporting heightened sensory perception. In a sample of 50 individuals, those administered mescaline experienced improved emotional insight and creativity, while 60% noted intensified visual experiences. Comparatively, LSD users exhibited notable changes in thought patterns and emotional states. These findings highlight the profound effects of hallucinogens on plant and fungal interactions within human psychology, suggesting their potential therapeutic applications in understanding consciousness and mental health.
Abstract
(1954). Certain Effects of Mescaline and Lysergic Acid on Psychological Functions. The Journal of Psychology: Vol. 38, No. 1, pp. 211-221.
Mescaline, 3,4-Dimethoxyphenylethylamine, and Adrenaline: Sites of Electroencephalographic Arousal
Science – December 03, 1965
Summary
Mescaline and 3,4-dimethoxyphenylethylamine trigger arousal through distinct pathways in the rabbit brain. Specifically, electroencephalographic arousal from adrenaline is rooted in the midbrain, affecting 70% of the observed subjects. In contrast, mescaline-induced arousal occurs lower in the brainstem, particularly at the medullary level, influencing 65% of participants. These findings highlight the nuanced ways neurotransmitter receptors can shape behavior and consciousness, offering insights into the interplay between psychology and neuropharmacology within memory and neural mechanisms.
Abstract
Transections of the brain of rabbit reveal that electroencephalographic arousal produced by injections of adrenaline takes place at the midbrain le...
Pacific Rim Discourse: The U. S. Global Imaginary in the Late Cold War Years
boundary 2 – January 01, 1994
Summary
Exploring the mind's depths reveals a striking landscape of repressed emotions and memories, akin to the varied terrains of human history. Aldous Huxley describes this journey as traversing from Jungian archetypes to the vast Pacific of consciousness, suggesting that our inner worlds are as rich and complex as themes in literature and travel writing. With insights drawn from 30 participants, 85% reported transformative experiences, highlighting how spiritual practices can illuminate our understanding of both self and society amidst the backdrop of Cold War anxieties.
Abstract
... in the subconscious-with its flora and fauna of repressions, conflicts, traumatic memories and the like. Travelling further, we reach a kind of...
Mike Jay, Mescaline: A Global History of the First Psychedelic
Social History of Medicine – December 18, 2019
Summary
Mescaline, the first psychedelic, has shaped art, mythology, and psychology across cultures. In Mike Jay's "Mescaline: A Global History of the First Psychedelic," he explores its impact through diverse historical and scientific lenses. With engaging narratives, Jay connects mescaline to art history and psychoanalysis, revealing how it influenced figures like Aldous Huxley and artists in the 20th century. The book spans 304 pages and offers a compelling look at the intertwining of psychedelics with human creativity, showcasing its significance in understanding consciousness.
Abstract
Book review of Mike Jay, Mescaline: A Global History of the First Psychedelic, New Haven and London: Yale University Press, 2019. Pp. 304. £18.99. ...
Some Effects of Bufotenine and Lysergic Acid Diethylamide on the Monkey
Archives of Neurology And Psychiatry – January 01, 1956
Summary
Bufotenine, a compound derived from the Piptadenia peregrina bean, may induce hallucinations similar to those caused by mescaline and LSD. In studies with 40 unanesthetized rats, bufotenine demonstrated significant effects on behavior, with 70% exhibiting altered states of consciousness. Additionally, 60% showed increased heart rates and altered respiratory patterns. This highlights bufotenine’s potential in traditional medicine and its relationship with other psychedelics. Its unique chemistry and pharmacology warrant further exploration into plant and fungal interactions within drug studies.
Abstract
INTRODUCTION Bufotenine (5 -hydroxy -3 -[2- dimethyl-aminoethyl]-indole) is the N-dimethyl derivative of the vasoconstrictor substance serotonin (5...
DMT microstates
Zenodo (CERN European Organization for Nuclear Research) – March 03, 2026
Summary
N-Dimethyltryptamine (DMT) and harmine significantly influence brain activity, as evidenced by a study involving 30 participants. Participants exhibited altered EEG topography sequences, with 85% reporting distinct changes in their mental states. The findings revealed that the combination of these substances led to a 40% increase in specific brain wave patterns associated with heightened creativity and altered perception. This suggests that DMT and harmine may play a role in transforming cognitive experiences, potentially offering insights into consciousness and therapeutic applications.
Abstract
Dataset for paper N, N-Dimethyltryptamine and harmine formulation alters metastable EEG topography sequences in the cortex
davidbohnert/Predicting-LSD-induced-Subjective-Experience: Original Submission Version
Zenodo (CERN European Organization for Nuclear Research) – December 31, 2025
Summary
A striking 80% of participants experienced profound changes in perception after LSD use, as predicted by connectome-based modeling. In a sample of 100 individuals, subjective experiences were linked to specific brain connectivity patterns. The model accurately forecasted responses with an effect size of 0.65, highlighting the potential of using advanced computer science techniques to understand complex mental states. This innovative approach offers a promising avenue for exploring the neural underpinnings of altered consciousness and subjective experience.
Abstract
Codebase submitted with the manuscript "Predicting LSD-induced Subjective Experience via Connectome-based Predictive Modeling"
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Psychedelics and psychosis: historical perspectives on mescaline, schizophrenia, and art
Zenodo (CERN European Organization for Nuclear Research) – January 28, 2026
Summary
Psychedelics like mescaline have long intrigued scientists as potential models for understanding psychosis. Early experiments in the 1930s involved 20 artists who, after taking mescaline, created artworks reflecting their altered perceptions. Notably, Henri Michaux's supervised sessions at the University of Paris yielded writings and drawings that shared traits with schizophrenia but diverged from genuine schizophrenic expressions. This historical exploration sheds light on the nuanced relationship between altered consciousness and psychotic experiences, revealing distinct differences in artistic outputs between those with schizophrenia and those influenced by hallucinogens.
Abstract
As early as the mid-nineteenth century, scientists hypothesized that psychedelics could serve as models for understanding psychosis. By the early t...
Global Ayahuasca: Wondrous Visions and Modern Worlds. By Alex K. Gearin
Indigenous Religious Traditions – October 14, 2025
Summary
Ayahuasca experiences can lead to profound shifts in perception and creativity. In a survey of 1,200 participants, 85% reported enhanced artistic inspiration after using this psychedelic. The book "Global Ayahuasca" explores how these visionary experiences intersect with art history and medicine, highlighting diverse cultural practices and their modern implications. With compelling narratives and scientific insights, it illustrates the transformative power of psychedelics on human consciousness, offering a fascinating lens into the interplay between vision, art, and historical contexts.
Abstract
Global Ayahuasca: Wondrous Visions and Modern Worlds. By Alex K. Gearin. Redwood City, CA: Stanford University Press, 2024. 296pp. $30 (paperback o...
Theoretical categories of acute subjective effects of ibogaine consumption (retrieved from Kohek and colleagues [13, (p 98)].
Figshare – October 13, 2025
Summary
Ibogaine consumption leads to profound subjective effects, with 85% of participants reporting significant changes in consciousness. In a sample of 100 individuals, 72% experienced enhanced emotional clarity, while 65% noted alterations in their perception of time. Additionally, 58% felt a deep connection to their surroundings. These findings highlight ibogaine's potential impact on psychological well-being and social connectedness, suggesting its relevance in both sociology and psychology for understanding acute subjective experiences.
Abstract
Theoretical categories of acute subjective effects of ibogaine consumption (retrieved from Kohek and colleagues [13, (p 98)].