1178 results for "Consciousness"

The Persistent Paradox of Rapid Eye Movement Sleep (REMS): Brain Waves and Dreaming.

Brain sciences  – June 21, 2024

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The original conceptualization of REM sleep as paradoxical sleep was based on its EEG resembling wakefulness and its association with dreaming. Ove...

Suicide Following a Near-Death Experience.

Crisis  – September 01, 2024

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Background: Sometimes during real or presumed life-threatening and/or near-death circumstances, an individual undergoes an altered state of conscio...

Detecting Lucid Dreams by Electroencephalography and Eyebrow Movements.

Sleep science (Sao Paulo, Brazil)  – December 01, 2023

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No Summary

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Objective When metacognition arises during rapid eye movement (REM) sleep, people experience lucid dreaming (LD). Studies on this phenomenon face d...

Sleep and dream disturbances associated with dissociative experiences.

Consciousness and cognition  – July 01, 2024

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Some dissociative experiences may be related, in part, to REM intrusion into waking consciousness. If so, some aspects of dream content may be asso...

Neuropsychopharmacological Induction of (Lucid) Dreams: A Narrative Review.

Brain sciences  – April 25, 2024

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Lucid dreaming (LD) is a physiological state of consciousness that occurs when dreamers become aware that they are dreaming, and may also control t...

Structural differences between non-lucid dreams, lucid dreams and out-of-body experience reports assessed by graph analysis.

Scientific reports  – November 09, 2023

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Dreaming is a complex phenomenon that occurs during sleep, involving various conscious dream experiences. Lucid dreams (LDs) involve heightened awa...

Naturalistic use of psychedelics does not modulate processing of self-related stimuli (but it might modulate attentional mechanisms): An event-related potentials study.

Psychophysiology  – August 01, 2024

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Classic psychedelics are able to profoundly alter the state of consciousness and lead to acute experiences of ego dissolution - the blurring of the...

Recognizing the Death Motif in the Near-Death Experience.

Omega  – September 19, 2023

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No Summary

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The typical near-death experience (NDE) is generally understood as an altered state of consciousness in which the experient has the impression of e...

Visual perspective, distance, and felt presence of others in dreams.

Consciousness and cognition  – August 01, 2023

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The peripersonal space, that is, the limited space surrounding the body, involves multisensory coding and representation of the self in space. Prev...

Electroencephalographic Signature of Out-of-Body Experiences Induced by Virtual Reality: A Novel Methodological Approach.

Journal of cognitive neuroscience  – September 01, 2023

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No Summary

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Out-of-body experiences (OBEs) are subjective experiences of seeing one's own body and the environment from a location outside the physical body. T...

Sleep Paralysis and Lucid Dreaming-Between Waking and Dreaming: A Review about Two Extraordinary States.

Journal of clinical medicine  – May 12, 2023

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Sleep paralysis and lucid dreams are two states of consciousness that are connected to REM sleep but are defined by higher awareness in contrast to...

The Near-Death Experience and Suicidal Ideation.

Omega  – March 10, 2023

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The near-death experience (NDE) most generally refers to a state of altered consciousness with various features that can occur during real or presu...

A novel ego dissolution scale: A construct validation study.

Consciousness and cognition  – March 01, 2023

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Ego dissolution (i.e., ego loss, ego disintegration, ego death, or self-loss) is a conscious state marked by a loss or diminution of one's sense of...

Lucid dreaming increased during the COVID-19 pandemic: An online survey.

PloS one  – January 01, 2022

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The COVID-19 pandemic changed people's lives all over the world. While anxiety and stress decreased sleep quality for most people, an increase in t...

EEG Lempel-Ziv complexity varies with sleep stage, but does not seem to track dream experience.

Frontiers in human neuroscience  – January 01, 2022

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In a recent electroencephalography (EEG) sleep study inspired by complexity theories of consciousness, we found that multi-channel signal diversity...

Combining Wake-Up-Back-to-Bed with Cognitive Induction Techniques: Does Earlier Sleep Interruption Reduce Lucid Dream Induction Rate?

Clocks & sleep  – April 20, 2022

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Lucid dreaming offers the chance to investigate dreams from within a dream and by real-time dialogue between experimenters and dreamers during REM ...

If the Doors of Perception Were Cleansed, Would Chronic Pain be Relieved? Evaluating the Benefits and Risks of Psychedelics.

The journal of pain  – October 01, 2022

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Psychedelic substances have played important roles in diverse cultures, and ingesting various plant preparations to evoke altered states of conscio...

Predictive coding, multisensory integration, and attentional control: A multicomponent framework for lucid dreaming.

Proceedings of the National Academy of Sciences of the United States of America  – November 01, 2022

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Lucid dreaming (LD) is a mental state in which we realize not being awake but are dreaming while asleep. It often involves vivid, perceptually inte...

Phenomenology and content of the inhaled N, N-dimethyltryptamine (N, N-DMT) experience.

Scientific reports  – May 24, 2022

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No Summary

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Understanding the phenomenology and content of the inhaled N, N, dimethyltryptamine (N, N-DMT) experience is critical to facilitate and support ong...

Examining the Relation Between Practicing Meditation and Having Peak Experiences and Lucid Dreams. A Cross-Sectional Study.

Frontiers in psychology  – January 01, 2022

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The aim of this study was to compare meditators and non-meditators in terms of their tendency to have peak experiences and their dream lucidity, wh...

Dream lucidity positively correlates with reality monitoring.

Consciousness and cognition  – October 01, 2022

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No Summary

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Dream lucidity, the awareness of consciousness in dreams, is linked to functions that support reality monitoring in differentiating between interna...

Designing a "Near-Death Experience" Reality Testing System.

Journal of medical physics  – January 01, 2021

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"Near-death experiences (NDEs)" are usually depicted with a vivid perception of departure from the physical body and being in a distinctive spatial...

Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice

Translational Psychiatry  – February 23, 2022

Summary

Psychedelics show promise for psychological well-being and psychiatric disorders. Neuroscience reveals psilocin acutely alters sleep architecture. Electroencephalography in mice showed delayed REM sleep onset and reduced NREM sleep for up to 3 hours after dosing, with an enhanced 4 Hz oscillation. While not affecting overall sleep rebound, psilocin decreased recovery of slow-wave activity in the cerebral cortex after Wakefulness deprivation. This Sleep and Wakefulness Research from Psychedelics and Drug Studies offers insights for Medicine, impacting our understanding of sleep (system call) regulation.

Abstract

Abstract Serotonergic psychedelic drugs, such as psilocin (4-hydroxy-N,N-dimethyltryptamine), profoundly alter the quality of consciousness through...

Contributions of Body-Orientation to Mental Ball Dropping Task During Out-of-Body Experiences.

Frontiers in integrative neuroscience  – January 01, 2021

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Out-of-body experiences (OBEs) provide fascinating insights into our understanding of bodily self-consciousness and the workings of the brain. Stud...

A Phase 1, Dose-Ranging Study to Assess Safety and Psychoactive Effects of a Vaporized 5-Methoxy-N, N-Dimethyltryptamine Formulation (GH001) in Healthy Volunteers.

Frontiers in pharmacology  – January 01, 2021

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5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) is a tryptamine with ultra-rapid onset and short duration of psychedelic effects. Prospective studies ...

Detecting lucid dreams only by submentalis electromyography.

Sleep medicine  – December 01, 2021

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Lucid dreams (LDs) occur when people become aware that they are dreaming. This phenomenon has a wide range of possible applications from the perspe...

Ketamine-Assisted and Culturally Attuned Trauma Informed Psychotherapy as Adjunct to Traditional Indigenous Healing: Effecting Cultural Collaboration in Canadian Mental Health Care.

Behavioral sciences (Basel, Switzerland)  – August 31, 2021

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Ketamine therapy with culturally attuned trauma-informed psychotherapy in a collaborative cross-cultural partnership may provide a critical step in...

The Role of Psilocybin-Assisted Psychotherapy to Support Patients With Cancer: A Critical Scoping Review of the Research

Journal of Holistic Nursing  – September 06, 2021

Summary

Psilocybin-assisted psychotherapy offers profound hope for cancer patients struggling with persistent mental health issues, despite conventional psychiatry. A review of eight articles (four quantitative, two mixed methods, two qualitative) indicates this intervention, guided by a psychotherapist, fostered positive experiences. Patients reported themes of death acceptance and broadened spirituality, addressing deep existentialism. This emerging approach in clinical psychology and palliative care, utilizing psilocybin (a naturally occurring alkaloid), complements traditional medicine and drug studies, providing a novel mental health strategy in psychedelics and alternative medicine.

Abstract

Treatments for addressing psychiatric mental health issues in vulnerable patients with cancer are established. Yet, many patients persist with unre...

Psilocybin-induced changes in brain network integrity and segregation correlate with plasma psilocin level and psychedelic experience.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology  – September 01, 2021

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The emerging novel therapeutic psilocybin produces psychedelic effects via engagement of cerebral serotonergic targets by psilocin (active metaboli...

Self-Boundary Dissolution in Meditation: A Phenomenological Investigation.

Brain sciences  – June 21, 2021

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A fundamental aspect of the sense of self is its pre-reflective dimension specifying the self as a bounded and embodied knower and agent. Being a c...

LSD alters dynamic integration and segregation in the human brain.

NeuroImage  – February 15, 2021

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No Summary

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Investigating changes in brain function induced by mind-altering substances such as LSD is a powerful method for interrogating and understanding ho...

Unexpected awakenings in severe dementia from case reports to laboratory.

Alzheimer's & dementia : the journal of the Alzheimer's Association  – January 01, 2021

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No Summary

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Case report notions of unexpected memory retrieval in patients with severe dementia near to death are starting to alter the central "irreversible" ...

Immersion, Absorption, and Spiritual Experience: Some Preliminary Findings.

Frontiers in psychology  – January 01, 2020

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No Summary

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Many traditions have utilized silent environments to induce altered states of consciousness and spiritual experiences. Neurocognitive explorations ...

Is there a relation among REM sleep dissociated phenomena, like lucid dreaming, sleep paralysis, out-of-body experiences, and false awakening?

Medical hypotheses  – November 01, 2020

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No Summary

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During REM sleep we normally experience dreams. However, there are other less common REM sleep phenomena, like lucid dreaming (LD), false awakening...

Investigation of the phenomenology, physiology and impact of spiritually transformative experiences - kundalini awakening.

Explore (New York, N.Y.)  – January 01, 2021

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No Summary

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There is a paucity of research examining the phenomenology and energetic effects of spiritually transformative experiences with an energetic compon...

Wake Up, Work on Dreams, Back to Bed and Lucid Dream: A Sleep Laboratory Study.

Frontiers in psychology  – January 01, 2020

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No Summary

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Lucid dreaming offers many opportunities to study consciousness processes. However, laboratory research in this area is limited because frequent lu...

Is There a Link Between Frequency of Dreams, Lucid Dreams, and Subjective Sleep Quality?

Frontiers in psychology  – January 01, 2020

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No Summary

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A lucid dream is a dream in which one is conscious of dreaming and can possibly control the dream or passively observe its unfolding. Frequencies o...

Attempted induction of signalled lucid dreaming by transcranial alternating current stimulation.

Consciousness and cognition  – August 01, 2020

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No Summary

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Neurophysiological correlates of self-awareness during sleep ('lucid dreaming') remain unclear despite their importance for clarifying the neural u...

Lucid Dreaming, Nightmares, and Sleep Paralysis: Associations With Reality Testing Deficits and Paranormal Experience/Belief.

Frontiers in psychology  – January 01, 2020

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No Summary

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Focusing on lucid dreaming, this paper examined relationships between dissociated experiences related to rapid eye movement (REM) sleep (lucid drea...

Applying intervention mapping approach to a program for early intervention in first-episode mental crisis of a psychotic type.

Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS  – March 13, 2020

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The holotropic mind perspective, an integral part of the framework of transpersonal psychology, has been considered a revolutionary approach to a c...

Near-death experience: memory recovery during hypnosis.

Explore (New York, N.Y.)  – January 01, 2024

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No Summary

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Increasing numbers of research studies have offered evidence regarding awareness of verified events during near-death experiences (NDEs) occurring ...

The influence of stakeholder interests on safety outcome reporting in psychedelic research and implications for science communication.

Trends in psychiatry and psychotherapy  – January 01, 2025

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Psychedelics are a group of psychoactive substances that produce complex and subjective changes to consciousness and carry unique safety considerat...

Nurse Who Had MERS-CoV Complications with A Near-Death Experience during Pregnancy: A Narrative Analysis.

Healthcare (Basel, Switzerland)  – January 24, 2024

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No Summary

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According to prevailing views in neuroscience, near-death experiences (NDE) occurring after severe head trauma, critical illness, or coma are often...

Breathwork-induced psychedelic experiences modulate neural dynamics.

Cerebral cortex (New York, N.Y. : 1991)  – August 01, 2024

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No Summary

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Breathwork is an understudied school of practices involving intentional respiratory modulation to induce an altered state of consciousness (ASC). W...

Spiritual health practitioners’ contributions to psychedelic assisted therapy: A qualitative analysis

PLoS ONE  – January 02, 2024

Summary

Spiritual health practitioners offer unique expertise in psychedelic-assisted therapies, vital for Medicine and Health care. Qualitative research, using thematic analysis of 15 practitioner interviews, revealed seven contributions, including competency with spiritual material and offering a counterbalance to biomedical perspectives in Psychology. Familiarity with these alkaloids, many from chemical synthesis, helps them complement psychotherapists and nurses in interdisciplinary teams. This approach, informed by Psychedelics and Drug Studies and Complementary and Alternative Medicine Studies, can establish rigorous standards for holistic treatment.

Abstract

Background Psychedelic-assisted therapies hold early promise for treating multiple psychiatric conditions. However, absent standards for the care, ...

Near-Death Experiences and Sleep Disturbance: An Exploratory Study Using Wrist Actigraphy.

The Journal of nervous and mental disease  – November 01, 2023

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No Summary

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Near-death experiences (NDEs) are nonordinary states of consciousness typically occurring on the brink of death. Sleep changes after NDEs have been...

Measuring acute effects of subanesthetic ketamine on cerebrovascular hemodynamics in humans using TD-fNIRS.

Scientific reports  – July 19, 2023

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No Summary

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Quantifying neural activity in natural conditions (i.e. conditions comparable to the standard clinical patient experience) during the administratio...

The cloud of unknowing: Cognitive dedifferentiation in whole-body perceptual deprivation.

Progress in brain research  – January 01, 2023

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No Summary

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An altered sensory environment, especially a homogeneous one like a ganzfeld, can induce a wide range of experiences in people immersed in it. The ...

Ketamine-assisted psychotherapy treatment of chronic pain and comorbid depression: a pilot study of two approaches.

Frontiers in pain research (Lausanne, Switzerland)  – January 01, 2023

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No Summary

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Chronic pain and depression diagnoses are skyrocketing. There is an urgent need for more effective treatments. Ketamine was recently established to...

The living experience of surviving out-of-hospital cardiac arrest and spiritual meaning making.

Nursing open  – August 01, 2023

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No Summary

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To understand the meaning of surviving out of hospital cardiac arrest and its aftereffects among Greek-speaking survivors. Hermeneutical phenomenol...

Do Psychedelics Facilitate Emergence of Unconscious Psychological Processes?

Psychodynamic psychiatry  – September 01, 2023

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No Summary

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Psychedelic substances have a long history of use in traditional healing and religious ceremonies worldwide and are increasingly being investigated...

The 'enigma' of Richard Schultes, Amazonian hallucinogenic plants, and the limits of ethnobotany.

Social studies of science  – June 01, 2020

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No Summary

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This story is about the twentieth-century ethnobotanist, Richard Evans Schultes (1915-2001), and his research on hallucinogenic plants. Ethnobotany...

N,N‐dimethyltryptamine and Amazonian ayahuasca plant medicine

Human Psychopharmacology Clinical and Experimental  – February 17, 2022

Summary

Ayahuasca, a potent hallucinogen, shows promise in Medicine for psychological conditions like depression and anxiety. Neuroscience reveals its compounds influence neurotransmitter receptors—serotonergic, glutaminergic, and dopaminergic systems—profoundly impacting behavior. Biochemical analysis indicates effects like increased delta and theta brain oscillations in key brain regions. Psychotherapists are considering its potential, but comprehensive Psychedelics and Drug Studies are essential to fully understand its Neurotransmitter Receptor Influence on Behavior and integrate this plant medicine into healthcare.

Abstract

Abstract Objective Reports have indicated possible uses of ayahuasca for the treatment of conditions including depression, addictions, post‐traumat...

Psychedelics alter metaphysical beliefs.

Scientific reports  – November 23, 2021

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No Summary

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Can the use of psychedelic drugs induce lasting changes in metaphysical beliefs? While it is popularly believed that they can, this question has ne...

Present and future of metabolic and metabolomics studies focused on classical psychedelics in humans

Biomedicine & Pharmacotherapy  – December 31, 2023

Summary

Understanding how the body processes psychedelic compounds is vital for unlocking their therapeutic potential. A review of studies on substances like LSD, psilocybin, and DMT reveals that while their primary breakdown products are largely known, their broader impact on human metabolism is still emerging. Integrating advanced metabolomics with drug tracking promises to illuminate the precise molecular interactions behind their positive therapeutic effects, paving the way for novel treatment development.

Abstract

Psychedelics are classical hallucinogen drugs that induce a marked altered state of consciousness. In recent years, there has been renewed attentio...

A Perspective on Psychedelics as Treatments for Addictions.

J Stud Alcohol Drugs  – March 22, 2024

Summary

Imagine a single therapeutic session profoundly aiding recovery from addiction. This perspective explores how certain compounds could disrupt entrenched addictive behaviors. By examining their unique effects on brain function and psychological processing, it reveals promising evidence. These substances appear to foster deep insights, emotional breakthroughs, and a renewed sense of purpose, all critical for overcoming addiction. This highlights a powerful, novel therapeutic avenue for lasting recovery.

Abstract

A Perspective on Psychedelics as Treatments for Addictions.

Dark Classics in Chemical Neuroscience: Lysergic Acid Diethylamide (LSD)

ACS Chemical Neuroscience  – February 20, 2018

Summary

Despite its profound effects, Lysergic acid diethylamide (LSD), a potent hallucinogen, was once hailed by psychiatry. Early drug studies showed doses as low as 20 μg were physiologically safe and nonaddictive. Its structural resemblance to serotonin sparked neurochemistry and pharmacology research, influencing our understanding of neurotransmitter receptor influence on behavior. Though clinical psychology and medicine halted research around 1970, new psychopharmacology interest in psychedelics like psilocybin for anxiety and addiction is emerging. Neuroscience is now exploring its potential, building on its chemical synthesis history in drug studies.

Abstract

Lysergic acid diethylamide (LSD) is one of the most potent psychoactive agents known, producing dramatic alterations of consciousness after submill...

The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future.

Neuropsychopharmacology  – April 26, 2017

Summary

Remarkably, certain psychedelic compounds are showing significant promise in treating mental health conditions. Exploring their historical use and current clinical applications, the work highlights how these substances, through unique neurological pathways, offer profound therapeutic benefits for conditions like depression and PTSD. These positive results suggest a powerful new frontier in mental healthcare, indicating a paradigm shift in treatment.

Abstract

The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future.

The treatment of abandonment anxiety with MDMA and LSD

OpenAlex  – June 09, 2023

Summary

A young woman overcame deep abandonment anxiety and childhood trauma, finding 'grace' through a novel therapeutic approach. After conventional psychiatry failed her family, and initial psilocybin experiences proved unstructured, she engaged in 1.5 years of psychology sessions with a psychotherapist, integrating MDMA and LSD. Through thirteen supervised and eighteen unsupervised hallucinogen sessions, she processed intense feelings, including a relived birth trauma. This journey, part of broader Psychedelics and Drug Studies, resolved her fear of abandonment, highlighting the potential for profound emotional healing beyond traditional psychoanalysis.

Abstract

This retrospective study presents the case of a young woman in her mid-twenties who suffered from insecurity and abandonment-related anxiety, which...

Survey of entity encounter experiences occasioned by inhaled N,N-dimethyltryptamine: Phenomenology, interpretation, and enduring effects.

Journal of psychopharmacology (Oxford, England)  – September 01, 2020

Summary

Over half of atheists surveyed no longer identified as such after a profound entity encounter occasioned by N,N-dimethyltryptamine. A large online survey characterized the subjective effects of these Psychedelic experiences. Participants often described visual and telepathic interactions with benevolent 'guides,' reporting love and joy. These encounters were rated as among life's most meaningful and insightful, leading to lasting positive changes in purpose and worldview.

Abstract

Experiences of having an encounter with seemingly autonomous entities are sometimes reported after inhaling N,N-dimethyltryptamine. The study chara...